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ARHGEF6 (NM_004840) Human Untagged Clone
CAT＃: SC100230
ARHGEF6 (untagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6)
CN¥ 5,688.00
CN¥ 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | alpha-PIX; alphaPIX; Cool-2; COOL2; MRX46; PIXA |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_004840 edited
ATGAATCCAGAAGAACAAATCGTGACATGGCTTATATCTTTGGGAGTTTTAGAGTCCCCT AAAAAGACCATCTGTGATCCGGAGGAGTTTTTAAAGTCCTCGCTGAAAAATGGGGTAGTT CTGTGCAAACTGATCAACAGACTCATGCCTGGCTCTGTGGAAAAGTTTTGTCTGGATCCC CAAACTGAAGCTGACTGCATCAACAACATCAATGACTTCCTGAAAGGATGTGCAACCCTC CAAGTGGAAATATTTGATCCTGATGACCTTTATTCAGGGGTCAATTTCTCCAAGGTACTG AGTACTCTTTTAGCTGTCAACAAAGCAACAGAAGATCAGCTATCAGAAAGACCATGTGGA CGTTCCTCTTCTCTTAGTGCTGCTAATACTTCTCAGACAAACCCACAGGGAGCAGTTTCT AGCACAGTTTCAGGGCTGCAAAGGCAGTCAAAGACAGTGGAGATGACGGAAAATGGAAGT CATCAGTTGATAGTAAAAGCAAGATTCAACTTTAAGCAGACTAATGAGGATGAACTGTCA GTTTGTAAGGGGGACATCATTTACGTCACACGAGTTGAAGAAGGAGGCTGGTGGGAAGGC ACATTAAATGGGAGAACAGGCTGGTTCCCCAGTAATTATGTCCGTGAAATTAAATCCAGT GAGAGACCTCTCTCCCCAAAAGCCGTCAAAGGATTTGAAACTGCTCCACTTACCAAGAAT TATTATACTGTGGTGTTACAGAACATCCTGGACACTGAAAAAGAATATGCTAAAGAACTT CAGTCTCTTCTTGTTACTTACTTAAGACCCCTGCAGTCCAATAACAATCTGAGTACTGTG GAGGTTACATCTTTACTGGGAAACTTCGAGGAAGTATGCACATTTCAACAGACACTCTGC CAAGCCTTGGAAGAATGTTCAAAGTTTCCAGAAAACCAGCACAAAGTAGGAGGTTGTCTA CTGAGTCTCATGCCTCATTTTAAATCTATGTATCTGGCTTACTGTGCAAACCATCCTTCA GCTGTAAATGTGCTCACTCAGCACAGTGATGAGTTGGAACAATTCATGGAAAATCAAGGT GCATCGAGCCCAGGTATCCTCATTTTAACAACAAACCTCAGCAAACCATTCATGCGACTG GAGAAATATGTTACTCTCTTGCAAGAGTTAGAACGGCATATGGAGGATACTCATCCAGAT CATCAGGATATTCTGAAAGCAATCGTAGCATTCAAAACTCTCATGGGGCAATGTCAAGAT CTGAGGAAGAGAAAACAGCTGGAGTTACAGATACTGTCCGAACCTATTCAGGCATGGGAA GGAGAAGATATTAAAAACTTGGGAAATGTGATTTTTATGTCACAAGTAATGGTGCAGTAT GGAGCATGTGAGGAAAAAGAGGAGCGGTACCTTATGTTATTTTCAAATGTCCTGATAATG TTATCTGCAAGTCCTCGGATGAGTGGCTTTATCTATCAGGGAAAAATACCAATAGCAGGA ACGGTGGTGACTAGATTAGATGAAATTGAAGGGAATGACTGCACATTTGAAATCACTGGT AACACAGTGGAGAGAATTGTGGTCCATTGTAACAACAACCAGGACTTCCAGGAATGGTTG GAGCAGCTGAACAGACTGATCAGAGGACCTGCCTCTTGCAGTTCATTATCCAAAACCTCA TCGTCATCATGTAGTGCTCATTCTTCTTTTAGCTCTACCGGACAGCCCCGAGGACCCTTG GAGCCTCCTCAAATTATAAAACCGTGGAGTTTAAGTTGTCTACGACCTGCACCTCCACTT AGACCATCAGCAGCACTAGGTTATAAAGAGAGGATGTCTTATATCTTAAAGGAGTCTAGT AAAAGCCCTAAAACGATGAAGAAATTTCTTCATAAAAGGAAGACTGAGAGAAAACCATCG GAGGAGGAATATGTGATTAGGAAAAGTACAGCTGCTCTGGAAGAGGATGCTCAAATCCTT AAAGTGATCGAAGCCTACTGCACCAGCGCAAATTTTCAACAAGGCCATGGCTCAAGTACT CGAAAAGATTCCATTCCACAAGTCCTACTCCCTGAGGAAGAGAAACTCATCATTGAAGAA ACCAGAAGCAACGGCCAGACCATCATGGAAGAAAAGAGCCTTGTTGATACTGTTTACGCC TTGAAGGACGAGGTCAGAGAACTGAAGCAGGAAAATAAAAGAATGAAGCAATGCCTGGAA GAAGAACTGAAATCAAGAAGGGACCTAGAAAAGCTGGTGCGGAGGCTTTTGAAGCAAACA GATGAGTGTATTCGAGGCGAGTCCAGTAGCAAGACCTCAATTCTTCCATAA |
| Restriction Sites | Please inquire |
| ACCN | NM_004840 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004840.2, NP_004831.1 |
| RefSeq Size | 5282 bp |
| RefSeq ORF | 2331 bp |
| Locus ID | 9459 |
| UniProt ID | Q15052 |
| Domains | RhoGEF, SH3, CH, PH |
| Protein Families | Druggable Genome |
| Protein Pathways | Pancreatic cancer, Regulation of actin cytoskeleton |
| Gene Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific cognitive disability. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208074 | ARHGEF6 (Myc-DDK-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CN¥ 5,688.00 |
|
| RC208074L1 | Lenti-ORF clone of ARHGEF6 (Myc-DDK-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CN¥ 7,700.00 |
|
| RC208074L2 | Lenti-ORF clone of ARHGEF6 (mGFP-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CN¥ 8,088.00 |
|
| RC208074L3 | Lenti-ORF clone of ARHGEF6 (Myc-DDK-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CN¥ 7,700.00 |
|
| RC208074L4 | Lenti-ORF clone of ARHGEF6 (mGFP-tagged)-Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CN¥ 7,700.00 |
|
| RG208074 | ARHGEF6 (tGFP-tagged) - Human Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 (ARHGEF6) |
CN¥ 6,370.00 |
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