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Eif3c (NM_001100662) Rat Untagged Clone
CAT＃: RN215246
Eif3c (untagged ORF) - Rat eukaryotic translation initiation factor 3, subunit C (Eif3c), (10 ug)
CNY 11,780.00
货期*
7周
规格
| Cited in 1 publication. |
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Eif3s8 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN215246 representing NM_001100662
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCCGGTTTTTCACCACCGGCTCGGACAGTGAGTCGGAGTCGTCCCTGTCCGGGGAGGAGCTCGTCA CCAAACCAGTCTCCGGGAACTATGGCAAACAGCCTTTGTTACTGAGCGAGGATGAAGAGGATACAAAGAG AGTTGTTCGAAGTGCCAAGGACAAGAGGTTTGAGGAGCTGACCAACCTTATACGAACCATCCGTAATGCC ATGAAGATTCGAGATGTCACCAAGTGTCTAGAAGAGTTTGAACTCCTGGGAAAAGCCTATGGGAAAGCCA AGAGTATTGTGGATAAGGAGGGTGTCCCCCGATTCTATGTCCGGATATTGGCTGACCTGGAGGACTATCT TAATGAGCTTTGGGAAGATAAGGAAGGGAAAAAGAAGATGAATAAAAACAATGCCAAGGCTCTGAGTACA TTGCGCCAGAAGATCCGAAAATACAACCGAGATTTTGAGTCTCACATCACCAACTATAAGCAGAACCCTG AACAATCTGCAGATGAAGATGCAGAAAAGAATGAGGAAGACTCAGAAGGCTCTTCAGATGAGGATGAAGA TGACGATGGAGTCAGTGGTACAGCCTTCTTGAAGAAGAAACCAGACTCTTCTGGGGAGAGTCGAAAGTTC CACAAAAAGATGGAGGATGATGATGAGGACTCTGAAGATTCTGAGGATGAAGAATGGGACACCAGTTCCA CATCTTCTGATTCAGACTCCGAAGAAGAAGAAGGAAAACAAACTGTTCTGGCCTCAAAGTTCCTTAAAAA GGCACCCACCACAGAGGAGGACAAAAAGGCAGCTGAAAAGAAACGGGAAGACAAAGCCAAGAAGAAGCAC GATAGGAAGTCTAAGCGCATGGATGAGGAAGAGGAGGACAATGAAGGCGGGGAGTGGGAACGGGTCCGAG GCGGCGTACCACTTGTTAAGGAGAAACCAAAAATGTTTGCCAAGGGAACAGAGATCACTCATGCTGTTGT CATCAAGAAGCTGAATGAGATTCTACAGGTCAGAGGCAAGAAGGGAACAGACCGTGCTACCCAGATTGAA TTGCTCCAGCTGCTGGTTCAGATTGCTTCTGAAAACAACCTGGGGGTGGGTGTCATTGTCAAGATCAAGT TCAATATCATTGCCTCTCTCTACGATTACAACCCTAACCTGGCCACGTACATGAAGCCAGAGATGTGGCA GATGTGCCTGGACTGTATCAATGAGTTGATGGATACCTTGGTTGCACATTCCAACATCTTTGTTGGAGAG AACATTTTGGAAGAGAGTGAGAACTTACACAATTTTGATCAGCCACTGCGTGTACGAGGCTGCATCCTAA CTCTGGTGGAGCGAATGGATGAAGAATTTACCAAAATAATGCAAAATACTGATCCTCACTCCCAAGAGTA TGTGGAACATCTGAAGGATGAGGCACAAGTATGTGCCATCATTGAGCGTGTACAGCGCTACCTGGAGGAG AAAGGTACCACTGAGGAGATCTGCCAGATCTACTTGAGGCGCATCCTGCACACTTACTACAAGTTTGATT ACAAGGCCCATCAGCGTCAGCTTACTCCTCCGGAAGGGTCCTCAAAGTCTGAGCAAGACCAGGCAGAAAA TGAGGGTGAGGACTCAGCTGTGCTAATGGAAAGACTGTGCAAATACATCTATGCCAAGGACCGTACAGAC CGCATCCGTACCTGTGCCATCCTCTGCCATATCTACCATCATGCGCTCCACTCCCGCTGGTATCAGGCCC GTGACCTCATGCTCATGAGCCACCTACAAGACAACATCCAGCACGCAGACCCGCCAGTACAGATCCTGTA TAACCGTACCATGGTGCAACTGGGCATCTGTGCTTTCCGCCAAGGCCTGACAAAGGATGCACACAATGCA CTTCTGGATATTCAGTCAAGTGGTCGTGCCAAGGAGCTTCTGGGCCAGGGTCTGCTGCTGCGCAGCCTCC AGGAGCGCAACCAGGAACAGGAGAAGGTAGAGCGACGCCGGCAGGTGCCCTTTCACCTGCACATCAACCT GGAACTGCTGGAGTGTGTGTATCTGGTGTCTGCTATGCTCCTGGAGATCCCCTACATGGCTGCCCATGAG AGTGATGCCCGCCGACGCATGATCAGCAAGCAGTTCCATCACCAACTGCGGGTGGGCGAGCGGCAGCCCC TGCTAGGTCCTCCTGAGTCAATGAGGGAGCATGTGGTTGCTGCCTCCAAGGCCATGAAGATGGGTGACTG GAAGACCTGCCACAGTTTCATCATTAATGAAAAGATGAATGGGAAAGTGTGGGACCTTTTCCCTGAGGCT GACAAAGTTCGCACCATGCTAGTTCGGAAGATCCAGGAAGAGTCTCTGAGGACCTACCTTTTTACCTATA GCAGTGTCTATGACTCAATCAGTATGGAGACACTCTCAGATATGTTTGAGCTGGATCTGCCCACTGTTCA CTCCATCATCAGCAAGATGATCATTAATGAAGAATTGATGGCTTCCCTGGACCAGCCAACGCAGACGGTA GTGATGCACCGTACTGAGCCCACTGCCCAACAGAACTTGGCTCTGCAGCTGGCTGAGAAGCTTGGCAGCC TAGTGGAGAATAATGAACGTGTGTTTGACCATAAGCAAGGAACCTATGGCGGCTATTTCCGAGACCAAAA GGATGGCTACCGAAAAAATGAAGGCTATATGCGCCGTGGTGGCTACCGCCAGCAGCAGTCTCAGACAGCT TACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001100662 |
| Insert Size | 2736 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001100662.1, NP_001094132.1 |
| RefSeq Size | 3061 bp |
| RefSeq ORF | 2736 bp |
| Locus ID | 293484 |
| UniProt ID | B5DFC8 |
| Gene Summary | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Eukaryotic translation initiation factor 3 subunit C is associated with acquired resistance to erlotinib in non-small cell lung cancer
,null,
Oncotarget
,PubMed ID 30680067
[Eif3c]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR215246 | Eif3c (Myc-DDK-tagged ORF) - Rat eukaryotic translation initiation factor 3, subunit C (Eif3c), (10 ug) |
CNY 11,780.00 |
|
| RR215246L3 | Lenti ORF clone of Eif3c (Myc-DDK-tagged ORF) - Rat eukaryotic translation initiation factor 3, subunit C (Eif3c), (10 ug) |
CNY 13,400.00 |
|
| RR215246L4 | Lenti ORF clone of Eif3c (mGFP-tagged ORF) - Rat eukaryotic translation initiation factor 3, subunit C (Eif3c), (10 ug) |
CNY 14,820.00 |
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