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Mcm8 (NM_001106514) Rat Untagged Clone
CAT＃: RN213458
Mcm8 (untagged ORF) - Rat minichromosome maintenance complex component 8 (Mcm8), (10 ug)
CNY 10,640.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN213458 representing NM_001106514
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGTGGTGCATACAGAGGCAGAGGTTTTGGACGAGGACGATTCCAAAACTGGAAAAGAGGAAGAGGTG GTGGGAACTTCTCAGGAAGGTGGAGAGACAGAACTGACCTGAGTAAAGCTGCAGGAAATCATGCTTCTGA ACAAGCCTCACAACCTTTACTTCAACAGTCAACATTGGATCAGTTTATACCGTATAAGGGCTGGAAGCTT TACTTCTCTGAAGTTTACAGTAATAACTCTCCTCTTACTGAGAAGATCCAAGCATTTGAGAAATTTTTCA CAAGGCATATCGACTTATATGATAAGGATGAAATAGAAAGAAAGGGAAGCATCTTGGTGGATTTTAAAGA ACTGACAAAAGACAATGAAATAACTAACTTGATACCAGATATAGAAAATGCACTAAGAGATGCCCCTGAG AAAACACTGGCATGTATGGGACTGGCAATACATCAGGTATTAACTAAGGACCTTGAAAGGCACGCAGCTG AATTACAAGCTCAAGAGGGGTTGTGTAATGGTGGAGGAACCATGGTAAATGTGCCACATATTTATGCGAG AGTGTACAACTATGAGCCCTTAACACACCTCAAGAACATCCGAGCAACTTGCTATGGGAAGTACATCTCT ATAAGAGGGACAGTGGTTCGAGTCAGTAACATAAAGCCTCTGTGCACCAAAATGGCTTTTCAGTGTGCTG CATGTGGAGAGATTCAGAGCTTTCCTCTTCCGGATGGAAAATACAATCTTCCAACAAAGTGTCCTGTGCC TGCGTGTCGAGGGAGGTCATTTACGCCATTGCGCAGTTCTCCTCTCACCGTCACAATGGACTGGCAGTTG ATCAAAATCCAGGAGCTGATGTCTGATGCACAGAGAGAAGCTGGTCGGATCCCTCGAACCATAGAATGTG AACTTGTTCATGATCTTGTAGATAGCTGTGTCCCAGGAGATACGGTGACTGTTACTGGAATTGTCAAAGT TTCAAATAGTGAAGAAGGTTCTCGATCTAAGAATGATAAGTGCATGTTCCTTTTGTACATTGAAGCAAAC TCTGTTAGCAACAGCAAAGGACAGAAAGCCCAGACTGCAGAGGATGGTTGCAAGCATGGAACACTGATGG AGTTCTCCCTTAAAGACCTGTATGCCATCCAAGAGATCCAGGCTGAAGAGAACCTGCTCAAGCTCATTGT CAACTCACTTTGTCCTGTCATTTTTGGTCATGAACTTGTTAAAGCAGGACTGATGTTAGCGCTATTTGGC GGTAGCCAGAAGTACGCAGATGACAAAAACAGGATTCCTATTCGAGGAGACCCACACGTCCTGATTGTTG GAGATCCAGGCTTGGGGAAGAGTCAGATGCTGCAGGCAGCATGCAACGTGGCGCCACGTGGTGTGTATGT TTGTGGAAATACGGCCACCAGCTCTGGTCTGACGGTTACTCTTTCAAAAGACAGTTCCTCAGGAGACTTC GCTTTGGAAGCTGGTGCCCTGGTACTTGGTGACCAAGGCATTTGTGGAATAGATGAATTTGATAAAATGG GGAATCAGCATCAAGCCTTGTTAGAAGCCATGGAACAGCAGAGCATTAGCCTTGCTAAGGCCGGTGTGGT TTGCAGCCTCCCTGCAAGAACCTCCATTATTGCTGCGGCAAATCCAGTCGGAGGACACTACAATAAAGCG AGGACAGTTTCTGAGAATTTAAAGATGGGGAGTGCCCTGCTGTCCAGGTTCGATTTGGTCTTTATCTTGT TAGATACACCAAATGAACAGCACGACCACTTACTTTCTGAACATGTGATCGCAATAAGAGCTGGGAAGCA GAGAGCGGTTAGCAGTGCCACAGTCTCTCGTGTGCTCAGTCAAGACTCAAATACTTCTGTACTTGAAGTG GTTTCCGAGAAACCGTTATCAGAAAGACTAAAGGTGGCTCCTGGAGAAAAGACAGATCCGATTCCACATC AGCTGCTGAGGAAGTACATAGGCTATGCACGGCAGTATGTCCATCCAAGGTTATCCACGGAAGCTGCTCA GGCTCTTCAGGATTTCTACCTGGAGCTGCGCAAGCAGAGCCAGCGCGTGGGCAGCTCGCCCATCACCACT CGGCAGCTGGAATCTTTGATCCGTCTGACGGAGGCACGAGCAAGGTTAGAATTGAGAGAGGAAGCAACTA AAGAAGACGCTGAAGATATAATTGAAATTATGAAGCATAGCATGCTAGGAACTTACTCAGATGAATTTGG AAACCTGGACTTTGAGCGATCCCAGCATGGCTCTGGAATGAGCAACAGGTCAACAGCTAAAAGATTTATT TCTGCTCTCAACAGCATTGCTGAAAGAACGTATAACAACATATTTCAATTTCATCAACTTCGTCAGATTG CTAAAGAGCTAAACATTCAGGTTGCTGACTTTGAAAACTTCATTGGATCACTGAATGACCAGGGTTATCT CCTGAAAAAAGGCCCAAAGATTTATCAACTTCAAACTATGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001106514 |
| Insert Size | 2493 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001106514.1, NP_001099984.1 |
| RefSeq Size | 3226 bp |
| RefSeq ORF | 2493 bp |
| Locus ID | 296178 |
| UniProt ID | D3ZVK1 |
| Gene Summary | Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross-links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex nuclease activity. Probably by regulating the localization of the MNR complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. The MCM8-MCM9 complex is dispensable for DNA replication and S phase progression. However, may play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Probably by regulating HR, plays a key role during gametogenesis. Stabilizes MCM9 protein.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR213458 | Mcm8 (Myc-DDK-tagged ORF) - Rat minichromosome maintenance complex component 8 (Mcm8), (10 ug) |
CNY 10,640.00 |
|
| RR213458L3 | Lenti ORF clone of Mcm8 (Myc-DDK-tagged ORF) - Rat minichromosome maintenance complex component 8 (Mcm8), (10 ug) |
CNY 12,450.00 |
|
| RR213458L4 | Lenti ORF clone of Mcm8 (mGFP-tagged ORF) - Rat minichromosome maintenance complex component 8 (Mcm8), (10 ug) |
CNY 13,590.00 |
