Lrpprc (NM_001008519) Rat Untagged Clone

Specifications

Product Data
Type	Rat Untagged Clone
Tag	Tag Free
Synonyms	Lrp157
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >RN211373 representing NM_001008519 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCAGCCCTGCTGAGACCCGCGCGTTGGCTGCTAGGGGCAGCGGCGGTCCCGCGCCTCCCGCTGTCCC TGCGCCTCCCTGCGGGCGGCCCCGGCAGGCTGCCCTCTGTCGTCCGGGTGGCGGCCGCTGGTGGCCGGCC GGCTGCAGGAGAGCTGCTGAGCCAAGCCAGGTTGTATGCCATCGTCGCTGAAAAAAAGGATCTTCCAGAG GAGCCTGCTCCTGTGAGAAGGAGTGGCAGTCAGTTTGATTGGGCCCTAATGAGACTGGATAATTCTGTCC GGAGAACGGGCCGCATTACCAAGGGGCTTCTGCAGAAAGTCTTTGAGAGCACGTGCCGCTCAGGGAGCCC AGGGAGTAACCAGGCCTTGCTTCTGCTGCGCAGCTGCGGCTCGCTCCTGCCCGAACTGAGTCTTGCAGAG AGGACAGAATTTGCTCATAAGATATGGGACAAACTTCAGCAGTTAGGCACTGTGTACGATGTCAGTCATT ATAATGCTTTACTTAAAGTATATCTTCAAAATGAATACCGATTCTCACCTACTGACTTCCTGGCAAAGAT GGAGGGAGCAAACATTCAACCGAACCGAGTGACATACCAGAGGCTGATCGCTGCCTATTGTAGTGTTGGG GACATTGAAGGCGCCAGCAAGATCCTTGGATTTATGAAAACGAGGGACCTTCCAATCACAGAGGCTGTGT TCAGTGCGCTCGTCACAGGGCACGCCAGAGCTGGGGATATGGAGAGTGCAGAGAATATTCTCACAGTGAT GAAACAGGCTGGCATTGAGCCTGGGCCAGACACGTATCTGGCCTTGTTGAACGCACATGCTGAGAAGGGT GACATTGACCATGTTAAGCAGATTCTGGAGAAAGTGGAAAAATCGGATCATTACTTTATGGACCGTGATT TCTTGCAAATTATTGTTAGCTTTAGTAAAGCTGGATATCCTCAGTATGTCTCAGAAATTTTGGAGAAGAT TACCTATGAGAGAAGATCTATTCCAGATGCAATGAACCTCATTTTGCTTTTAGTCACTGAGAAGTTAGAA GACACGGCGTTCCAGGTTTTACTGGCATTACCCCTGGCCAGGGATGAGACCTCAAGTAGTTTTGGCAGTT TCTTTTTGCGGCACTGTGTGACTATGGATACGCCTGCTGAGAAGCTGATAGACTACTGTAAGAGACTGAG GGACGCCAAGGTGCACAGCTCTTCACTGCAGTTCACCCTGCACTGTGCTCTTCAAGCCAATAAGACTGCT TTGGCAAAAGCAGTGATGGAGGCTCTGAGGGATGAAGGGTTTCCTATCCGAACTCACTATTTCTGGCCGT TGCTTGTTGGACATCAGAAAACAAAAAATGTTCAAGGAATAATAGATATTCTTAAAATCATGAAGGAAAT GGGAGTGGATCCCGATCAGGAAACATACATAAATTATGTGTTTCCCTGCTTCGGTAGTGTGCAGTCGGCT CGAGCTGCTCTGCAGGAAAATAAATGTCTGCCTAAAAGTACTACATTCGCTCAAGCCGAAGTGAGAAATG AAGCAATAAATGGGAATTTACAGAACATTTTGTCATTTTTGGAATCGAATGCATTGCCTTTCTCGTTTAA TTCTTTGAGAGGCAGCCTAATTCTAGGCTTTAGGAGGTCGATGAATATAGATCTTTGGAGCAAGATAACA GAATTGCTGTACAAGGATGACCGTTATTGCCAAAAACCTCCAGGACCAACGGAAGCTGTTGGCTATTTTC TTTATAACTTGATTGACAGCATGAGTGACTCAGAGGTGCAGGCCAAGGAGGAGCGCTTGAGACAATACTT CCATCAGCTTCGAGAAATGAATGTTAAAGTTTCTGAAAACATCTACAAAGGCATTTGTAATTTGCTGGAT AACTACCATGTTCCTGAATTGATTAAGGATGTTAAGGTTCTGGTTGACAGAGAGAAGATAGATTCTCGAA AAACCTCCCAGTTTACCTCATCTGATTTGGAGTCAACCCTTGAGAAGCTTAAAGCTGAAGGCCATCCTGT AGGAGACCCCCTGAAGCAGCTCATCTTGCTGCTCTGTTCTGAGGAGAATATGCAAAAGGCCCTTGAAGTG AAAGCAAAATACGAGTCAGACATGGTTATTGGAGGCTATGCAGCTTTAATAAATTTGTGCTGTCGACATG ATAATGCAGAAGATGCACTGAACTTGAAACAAGAATTTGACCGCTTAGATCCTTCAGCTGTTCTTGACAC TGCCAAGTATGTAGCCCTGGTAAAAGTATTGGGAAAGCATGGCAGAGTGCAAGATGCTATTAACATTCTA AAGGAGATGAAAGAGAAGGATGTTGTTATCAAAGATGCAGCAGTCTTGTCCTTCTTCCACATCCTGAATG GTGCAGCTTTAAGAGGTGAAATTGAGACAGTAAAACAGTTGCATGAAGCCATCGTGACTCTTGGGTTGGC AAAGCCATCCAGCAACATAAGCTTCCCATTGGTCACTGTGCACCTGGAAAAGGATGATTTACCTGCTGCT CTTGAAGCCAGCATTGCCTGCCATGAAAAATATAAAGTATTACCCAGGATTCATGATGTCTTATGTAAGC TAATAGAAAAAGGCGAGACTGACTTAATCCAGAAAGCGATGGACTTTGTCAGCCAAGAGCAGGGCGAGAT GTCGATGCTCTACGACCTCTTCTTTGCTTTCCTGCAGACGGGAAACTACAAAGAGGCCAAGAAGATTATT GAGACTCCAGGCATTAGAGCTCGGCCTACACGACTTCAGTGGTTTTGTGATAGATGCATTGCCAATAATC AGGTTGAAACTCTTGAGAAGTTAGTGGAGCTGACCGAGAAGCTGTTTGAATGTGACAGAGACCAGATGTA CTACAACTTACTGAAACTATACAAAATAAGCGGTGACTGGCAAAGAGCGGATGCTGTCTGGAATAAAATG CAAGAAGAGAATCTTATCCCTCGAGAACGGACACTGCGACTGTTAGCTGGGATCCTGAAAACCAGCAACC AGGAGGTTCCTTTTGACGTTCCTGAGTTGTGGTTTGGAGATGACAGGTCTTCCCTGAGTTCATCCTCACC CTCAGCAGGAGACACCGTGACTGAGAAGATGTTGTTGTCTGACTGCAGACTGAAGAAGAGTAAGGATGCA TATAATATCTTCCTCAAAGCCGAAAAGCAAGATGTCGTCTTCAGCAGTGAGGCTTACAGCACCCTGGTTG GCTTGCTGCTGAGCAAAGATGACTTCACACGAGCCATGCATGTGAAAGATTTCGCTGAGACCCACATCAA GGGCTTCACACTGAACGGTGCTGCCAGCAGCCTCCTCATCATCGCGCAAGTTAGGCGGGATTATTTGAAA GTGGCTCTAGAAACTCTGAAGGCAGCCTTGGATCTGGAACAGGTGCCTTCTGAGCTGGCCGTGACCCGCC TTATCCAGGCACTGGCCTTGCAGGGTGATGTGAAAAGCATAGAGACCATTCAGAAGATGGTGAAAGGGCT NGACGCGATTGAGCTCTCAAGAATGGTCTTCATCAACAACATTGCTCTGGCCCAGATGAAGAATAATGAA ATTGATGCTGCCATAGAAAATATCGAGCACATGCTTGCCTCAGAGAATCAGACCGTGGAACACCAGTACT TTGGCTTGTCGTACTTATTCAGGAAAGTGATAGAGGAGCAGATGGAGCCAGCGCTCGAAAAGTTAAGCAT CATGTCTGAGAGGTTGGCCAATCAGTTTGCACTTTACAAACCCGTCACTGATCTCTTCCTTCAGCTTGTG GATTCAGGCAAGGTGGATGAGGCCAGAGCCCTCTTGGAGAGATGCGGCGCCATTGCCGAGCAGACCTCAA TTCTGTCGGTGTTCTGTCTCAGGACGTCTCAGAAACCAAAAAAGGCCCCGGTTCTGAAGACCTTGTTAGA GCTGATTCCCGAGTTACGTGAGAATGACAGAGTGTACTCCTGCAGCATGAAAAGCTATGTCGCAGACAAA GACGTGGCCTCCGCTAAAGCGCTGTATGAGCATTTGACAGCAAAGAACATGAAGCTGGACGACCTCTTTT TGAAGCGCTACGCATCTTTGCTCAAGGATGTGGGCGAGCCGGTCCCCTTCACTGAGCCCCCTGAAAGCTT TGGATTTTACATAAAGCAACTAAAGGAAGCGAGAGAAAACCCCTCATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001008519
Insert Size	4179 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_001008519.1, NP_001008519.1
RefSeq Size	4336 bp
RefSeq ORF	4179 bp
Locus ID	313867
UniProt ID	Q5SGE0
Gene Summary	May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).[UniProtKB/Swiss-Prot Function]

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