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Gna13 (NM_001013119) Rat Untagged Clone
CAT＃: RN208034
Gna13 (untagged ORF) - Rat guanine nucleotide binding protein, alpha 13 (Gna13), (10 ug)
CNY 5,856.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Galpha13 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN208034 representing NM_001013119
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGACTTCCTGCCGTCGCGCTCCGTGCTGTCCGTGTGCTTCCCGGGCTGCGTGCTGACGAACGGCG AGGCCGAGCAGCAGCGCAAGTCCAAGGAGATCGACAAATGCCTGTCGCGGGAGAAGACCTACGTGAAGCG GCTGGTGAAGATCCTGCTGCTGGGCGCGGGCGAGAGCGGCAAGTCCACCTTCCTGAAGCAGATGCGGATC ATCCACGGCCAGGACTTCGACCAGCGCGCGCGCGAGGAGTTCCGCCCCACCATCTACAGCAACGTGATCA AAGGTATGAGGGTGCTGGTAGATGCCCGAGAGAAGCTTCATATTCCCTGGGGAGATAACAAAAACCAGGT CCACGGAGACAAGTTGATGGCATTTGATACCCGAGCTCCCATGGCTGCCCAGGGGATGGTGGAGACTCGA GTTTTTTTGCAGTATCTTCCTGCTATAAGAGCCTTATGGGATGACAGTGGCATACAGAATGCCTACGATC GGCGCCGGGAATTCCAACTGGGTGAGTCTGTAAAGTATTTCCTGGATAACTTGGATAAACTTGGAGTACC GGACTACATTCCGTCACAGCAAGATATTCTGCTTGCCAGAAGACCCACCAAAGGCATCCATGAGTATGAC TTTGAAATTAAAAATGTTCCTTTCAAAATGGTTGACGTAGGTGGCCAGAGATCAGAACGGAAACGTTGGT TTGAATGCTTTGACAGTGTGACATCAATACTCTTCCTTGTTTCTTCAAGTGAGTTTGACCAGGTGCTTAT GGAGGACCGCCTGACCAACCGCCTCACAGAGTCCCTGAACATTTTTGAAACAATTGTCAATAACCGGGTT TTCAGCAATGTCTCTATAATTCTCTTCTTAAACAAGACAGACTTGCTTGAGGAGAAAGTGCAAGTTGTAA GCATCAAAGACTATTTCCTAGAATTTGAAGGGGACCCTCACTGCTTAAGAGACGTCCAAAAGTTTCTGGT GGAATGCTTCCGGGGGAAACGCCGGGACCAGCAGCAGAGGCCGCTGTACCACCACTTCACCACCGCCATC AACACAGAGAACATCCGCCTTGTGTTCCGAGACGTGAAGGACACGATCCTTCATGACAACCTCAAGCAGC TTATGCTCCAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001013119 |
| Insert Size | 1134 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001013119.1, NP_001013137.1 |
| RefSeq Size | 1159 bp |
| RefSeq ORF | 1134 bp |
| Locus ID | 303634 |
| UniProt ID | Q6Q7Y5 |
| Gene Summary | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:12176367). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (By similarity). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (By similarity). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (By similarity). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR208034 | Gna13 (Myc-DDK-tagged ORF) - Rat guanine nucleotide binding protein, alpha 13 (Gna13), (10 ug) |
CNY 5,488.00 |
|
| RR208034L3 | Lenti ORF clone of Gna13 (Myc-DDK-tagged ORF) - Rat guanine nucleotide binding protein, alpha 13 (Gna13), (10 ug) |
CNY 6,080.00 |
|
| RR208034L4 | Lenti ORF clone of Gna13 (mGFP-tagged ORF) - Rat guanine nucleotide binding protein, alpha 13 (Gna13), (10 ug) |
CNY 6,650.00 |
