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Keap1 (NM_057152) Rat Untagged Clone
CAT＃: RN201988
Keap1 (untagged ORF) - Rat Kelch-like ECH-associated protein 1 (Keap1), (10 ug)
CNY 7,980.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | Inrf2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN201988 representing NM_057152
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCAGCCCGAACCCAAGCCTAGCGGGGCTCCCCGCAGCAGCCAGTTCCTGCCCCTGTGGTCAAAGTGCC CGGAGGGGGCAGGGGACGCGGTGATGTATGCATCCACGGAGTGCAAGGCGGAGGTGACGCCCTCGCAGGA TGGTAACCGAACCTTCAGTTACACACTAGAGGATCACACCAAGCAGGCTTTTGGCATCATGAACGAGCTT CGGCTGAGCCAGCAGCTCTGTGACGTGACCCTGCAGGTCAAATATGAGGACATCCCAGCTGCCCAATTCA TGGCCCACAAAGTGGTGCTGGCCTCCTCCAGCCCAGTCTTTAAAGCTATGTTCACCAACGGGCTTCGGGA GCAGGGCATGGAGGTGGTGTCCATTGAAGGCATCCACCCCAAGGTCATGGAGAGGCTAATTGAGTTCGCC TACACGGCCTCCATCTCCGTGGGCGAGAAGTGTGTGCTGCATGTGATGAACGGGGCAGTCATGTACCAGA TTGACAGCGTGGTCCGAGCCTGCAGCGACTTCCTCGTGCAGCAGCTGGACCCCAGCAACGCCATCGGCAT CGCCAACTTCGCCGAGCAGATCGGCTGCACGGAACTGCACCAGCGTGCTCGGGAGTATATCTACATGCAC TTCGGGGAGGAGGAGTTCTTCAACCTGTCACACTGCCAGCTGGCCACGCTCATCAGCCGCGATGATCTGA ACGTGCGCTGCGAGTCCGAGGTGTTCCATGCGTGCATCGACTGGGTCAAATACGACTGCCCGCAGCGGCG CTTCTACGTGCAGGCACTGCTACGGGCCGTGCGCTGCCACGCTCTCACGCCACGCTTCCTGCAGACACAG CTGCAAAAGTGCGAGATCCTGCAGGCCGACGCGCGCTGCAAGGACTACCTGGTGCAGATCTTCCAGGAGC TCACGCTGCACAAGCCCACACAAGCGGTGCCCTGCCGGGCGCCCAAAGTGGGCCGCCTCATCTACACTGC GGGCGGTTACTTCCGACAGTCGCTCAGCTACCTGGAGGCCTACAACCCGAGCAATGGCTCCTGGCTGCGC CTGGCAGACCTACAGGTGCCCCGCAGTGGGCTGGCGGGCTGCGTGGTGGGCGGGCTGCTGTATGCTGTGG GCGGCCGCAACAACTCGCCGGACGGCAACACTGATTCCAGCGCCCTGGACTGCTACAACCCCATGACCAA CCAGTGGTCGCCCTGTGCCTCTATGAGCGTGCCGCGCAACCGCATCGGGGTGGGGGTCATAGATGGCCAC ATCTACGCAGTCGGGGGTTCCCACGGCTGCATCCACCACAGCAGCGTGGAGAGATATGAGCCAGATCGAG ACGAGTGGCACCTAGTCGCGCCAATGTTGACGCGGAGGATCGGCGTGGGCGTGGCAGTGCTCAACCGCTT GCTGTATGCAGTGGGGGGCTTTGATGGGACTAACCGGCTTAACTCGGCAGAATGTTACTACCCGGAGAGG AATGAGTGGCGGATGATTACACCAATGAATACCATCCGGAGCGGGGCCGGGGTCTGTGTGCTGCACAGCT GCATCTATGCCGCAGGAGGCTACGATGGGCAGGACCAGCTGAACAGCGTGGAACGCTACGACGTGGAGAC AGAGACCTGGACTTTCGTAGCCTCCATGAAGCATCGCCGGAGCGCGCTGGGGATTGCTGTGCACCAGGGC AGGATCTACGTCCTCGGAGGCTACGATGGCCACACTTTTCTGGACAGTGTGGAATGCTATGACCCAGACA CTGATACCTGGAGTGAAGTGACCCGCTTGACATCTGGCCGCAGTGGGGTGGGTGTTGCTGTCACCATGGA ACCCTGTCGGAAGCAAATTGATCAACAAAACTGTACCTGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_057152 |
| Insert Size | 1863 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_057152.2, NP_476493.2 |
| RefSeq Size | 3162 bp |
| RefSeq ORF | 1863 bp |
| Locus ID | 117519 |
| Gene Summary | binds nuclear transcription factor Nrf2 and retains it in the cytoplasm thus inhibiting it from functioning in the nucleus [RGD, Feb 2006] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
,null,
Nature
,PubMed ID 29590092
[Keap1]
|
|
Characterization of RA839, a Noncovalent Small Molecule Binder to Keap1 and Selective Activator of Nrf2 Signaling
,null,
The Journal of Biological Chemistry
,PubMed ID 26459563
[Keap1]
|
|
Bromodomain and Extra-Terminal (BET) proteins suppress nuclear factor E2-related factor 2 (Nrf2) -mediated antioxidant gene expression
,null,
Journal of immunology (Baltimore, Md. : 1950)
,PubMed ID 24733848
[Keap1]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR201988 | Keap1 (Myc-DDK-tagged ORF) - Rat Kelch-like ECH-associated protein 1 (Keap1), (10 ug) |
CNY 5,080.00 |
|
| RR201988L3 | Lenti ORF clone of Keap1 (Myc-DDK-tagged ORF) - Rat Kelch-like ECH-associated protein 1 (Keap1), (10 ug) |
CNY 9,880.00 |
|
| RR201988L4 | Lenti ORF clone of Keap1 (mGFP-tagged ORF) - Rat Kelch-like ECH-associated protein 1 (Keap1), (10 ug) |
CNY 10,740.00 |
