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JMJD1C (NM_001282948) Human Tagged ORF Clone
CAT＃: RG240245
- TrueORF®
JMJD1C (tGFP-tagged) - Human jumonji domain containing 1C (JMJD1C), transcript variant 3
ORF Plasmid: DDK
"NM_001282948" in other vectors (2)
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CNY 27,270.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | KDM3C; TRIP-8; TRIP8 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG240245 representing NM_001282948.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATATAGACAAGACTCTGCCACCCAGTGG TTTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTACTA GAACCACAGAATGTCGATCCTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTA AAAGGTGAAAATATTGGCATTACATCACGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGTTCAC AGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCAGCAATGAACTCCCAAGCTGCTGTACCAAAA CAGAATACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCAGATAGCAGT ATACCAGATGAAGAGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGT AAAAACAAACACTTGATGAATAAAAGAAGGAAACCTGAGGAGGATGAAAAGAAACTAAATATGAAAAGA CTTCGAACTGACAATGTTTCAGACTTTTCTGAGAGCAGTGACTCAGAAAATTCAAATAAGAGAATAATA GATAATTCCTCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCAAAAATAAATGGAGAA GAAGGAAAACCCCATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGAT CAAATACAGGAAGATAAAAAACATGAAGAAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAA GATATGATTATTCATTCGTCAGAACAGTCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCTCAG GAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAGAAGTTTGTATCCAGACCACCC ACACCAAAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGT ACCTTTGGCCTTCAGACACTTCAGAAAATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAAT GCAAAATTCTTGGAAACAGCAAAAAAAGATTCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGAT CTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGATCACTTGAACATGGAAAAAGAGAAGTAT GTCTCTTACATTTCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGTCCACCT CCAGAGACTATAAAATCTAAACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCT GAAGTTGTTAAACCCAAAATAACTCATTCTCCTGATTCTGTAAAGTCTAAGGCCACTTATGTGAACAGC CAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATAGAACATGAGCTATCAAGATGCAGTTTTCATCCA ATTCCTACTCGAAGCAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAAAATGAGCATTTT ACAGTTTACAGAGATCCTGCACTTATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGC CAGCATCCTTTTCCTCTTCACTCCTCATCTCATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCC TTAACTCCTGCACCCCATTTACTAGCCGGATCATCTAGTCAAACTCCATTACCTACCATTAACACTCAT CCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCCACTGTGTTACCTGGAGTG CCTACTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTA GCGCTAGCACACCAGCAACAACAACAGTTGTTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCAT CCTTCTGCTTCATATAATCAGCTTGGACTTTATCCAATTATTTGGCAGTATCCAAATGGAACACATGCA TACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAAAATGCAGTTAATGCTGAAGCTTCA TTAAGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATTGGA TTACTTAGTCACATTCCTGTCAGACCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCAT TCCAGTCCACCATTGACAAAAACTTTAGTAGATCATCATAAGGAAGAATTAGAAAGAAAAGCTTTTATG GAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAATGACCTGGATCTAAATAGGTCACAGACTGGA AAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCACCCCAGGAG ACTGGAGAGAGGTTAAACAAATACAAAGAGGAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCT CCCTTTACAACTAAAATCAAGGGACTTGAGGGTGAGAGAGAGAATTATTCCAGAGTGGCATCATCATCT TCCAGTCCTAAAAGCCATATCATCAAACAAGATATGGATGTAGAACGCTCAGTATCAGATCTTTATAAA ATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTGTCTAATAGTGTGGTC AATGAACCACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGATAAACAGAGTAATGCC CTTGCAGCGGCAGCAGCTAATCCTCAAACTCTGACTTCATTTATAACATCTCTTTCAAAGCCTCCACCT TTGATTAAACACCAACCAGAAAGTGAAGGTTTAGTAGGCAAGATACCAGAACATCTTCCACATCAGATT GCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACCCATTTGACAGTTTCTTCTACA AATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTG GAAAGAAAGGAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCT GGTGGTAAAGTTCAAGAATCACAGAAGCCTCCAACTCTAATACCCGAACCAAAAGACTCCCAGGCAAAT TTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGACCTAATAATAACCTCAGCAAAGAGAAA ACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTGCGTCCA TCTTCTAGTACAAAAACTGATAGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGAGTTAGTGAAAGA TCTTCAGCTGGGGCACATAAAACAGATTGCCTCAAACTAGCAGAAGCCGGAGAAACTGGAAGAATCATT TTGCCAAATGTGAATTCAGACAGTGTTCACACAAAATCTGAAAAAAACTTTCAGGCTGTCTCACAGGGC AGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGATGTAATCACATCT GCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCATT TTGGCCTCTACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAGCCAGTGGCTCAAAAACAAGAA TGCAAGGTCAGCACCACAGCACCAGTTACATTAGCCAGTAGTAAGACAGGAAGTGTTGTTCAACCCAGT TCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCAGCATTGGCTGCAGCTCAG TATAAAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTT CCTCTGGATAGCACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCC CAGACAAGTCAACCAAACTACCATACTAAACTGAAAAAGGCCTGGCTCACCAGACACTCAGAAGAAGAT AAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAAATTATTAAGCCATGTTCTGTCAAC TTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATATGTA AAAGATGATAAAGTCAACAGGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCA GATGAAAGTGAAAGCAAGTCAGAGCAAAGGACTAAAAGACAACCTAAGCCAACTTACAAAAAGAAGCAA AATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGATTTGAAACCCAATGGAGTTCTCAGCAGGAGT GCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCAGTATTGAAA GATTGGCGTAAAGTCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAG ATAGGGCCTAATTTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAAAAAGGAGAAGAACCAGCT CACTCACCAGTATTTTGTAGATTTTACTACTTTAGACGGTTGTCATTTAGTAAAAACGGAGTAGTTAGA ATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGGACACATGAAAATTTT GAAGATGATGAACTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAA TTAGTAACATCTGAAAAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCA GTGAGAGGAGTCCGGGAGATGTGTGATGCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGCCAA AAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGGAAGAGTTCTAGAGATAAAGAA CTATATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATT ATACCTGGTTCTGTTTTGACAGATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAA TCCCATTGTCATTGTACTAACAAACAGAATTTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATCT CAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCTCTGTGCATGCCTGAGTCTCAGCAGCAA AATACTCCTCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGATAACAAG TTAACTCCTCCAGAATCCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAG GAAAAAAAAGAAAACAAAGAACTTACCCTTGAAAACCAAATTAAAGAAGAAAGAGAACAAGACAACTCT GAATCTCCAAATGGCAGAACATCACCTCTTGTGTCCCAGAATAATGAACAAGGCTCAACCTTACGGGAT TTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCCTTTGCCCCAGTA TATTCAATGGGAGCCCCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCT TCAGTTGTTGAAAACAAAATTCCACCAAGTAAAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAA GAGCCTGAAGAAAGCATAATATCTGCAGTGGATGAAAATAATAAATTATACAGTGATATACCACATTCT TGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGTAATTGGAAGCTTTTCAAA GAATGTTGGAAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGG AAGGCGGAATCAATTAGTCTTGATTTTGGAGACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATC ATTTCAAATGCCAATGTTAAGGAATTCTGGGATGGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAG AGTGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGAGAAGACTTCAAGACTATGATGCCA GCAAGATACGAAGATCTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTCAAT TTGGCCTCTCATTTGCCAGGATTTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGT GTAGTTGCTGCTAAAGATCATGATATAGGAACAACAAATCTCCATATTGAAGTTTCTGATGTTGTAAAT ATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATTCTCTCAAAAGCAGGAATTCTCAAGAAATTT GAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCTGGTGCTCTG TGGCATATTTATGCTGGGAAAGATGTTGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAA GGCCTTGAAGTTCTACCAGAACATGATCCAATACGTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGT CAAAGGCTGCTTGAAGAATATGGAGTCAGAACCTGTACTCTTATTCAGTTCCTTGGTGATGCTATTGTT TTGCCAGCGGGAGCACTTCATCAGGTTCAGAATTTTCACAGCTGTATTCAGGTAACTGAAGATTTTGTG TCTCCAGAACATCTTGTAGAGTCATTTCATTTAACACAGGAACTGAGACTTTTGAAGGAAGAAATCAAT TATGATGATAAACTACAGGTTAAAAATATTTTGTATCATGCAGTCAAAGAAATGGTGAGAGCCTTGAAG ATACACGAGGATGAAGTAGAGGATATGGAAGAAAAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG240245
Blue=ORF Red=Cloning site Green=Tag(s) MQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLL KGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSS IPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRII DNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDTQLQE DMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSS TFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKY VSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNS QATGERRLANKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLS QHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGV PTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHA YSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAH SSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQE TGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDMDVERSVSDLYK MKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPP LIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSL ERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEK TEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRII LPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTI LASTSSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQ YKSSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEED KNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGDS DESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLK DWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVR IDGFSSPDQYDDEAMSLWTHENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRA VRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERKSSRDKELYAWMKCVKGQPHDHKHLMPTQI IPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVLNHSNKISLCMPESQQQ NTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNS ESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIA SVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFK ECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEFWDGFEEVSKRQKNK SGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYG VVAAKDHDIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGAL WHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIV LPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELRLLKEEINYDDKLQVKNILYHAVKEMVRALK IHEDEVEDMEEN TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001282948 |
| ORF Size | 7074 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001282948.1, NP_001269877.1 |
| RefSeq Size | 8675 bp |
| RefSeq ORF | 7077 bp |
| Locus ID | 221037 |
| UniProt ID | Q15652 |
| Protein Families | Druggable Genome |
| MW | 263.6 kDa |
| Gene Summary | The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
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