RTEL1 (NM_001283009) Human Tagged ORF Clone
CAT#: RG240100
- TrueORF®
RTEL1 (tGFP-tagged) - Human regulator of telomere elongation helicase 1 (RTEL1), transcript variant 3
ORF Plasmid: DDK
"NM_001283009" in other vectors (2)
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CNY 13,400.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | C20orf41; DKCA4; DKCB5; NHL; PFBMFT3; RTEL |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG240100 representing NM_001283009.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCCCAAGATAGTCCTGAATGGTGTGACCGTAGACTTCCCTTTCCAGCCCTACAAATGCCAACAGGAG TACATGACCAAGGTCCTGGAATGTCTGCAGCAGAAGGTGAATGGCATCCTGGAGAGCCCTACGGGTACA GGGAAGACGCTGTGCCTGCTGTGCACCACGCTGGCCTGGCGAGAACACCTCCGAGACGGCATCTCTGCC CGCAAGATTGCCGAGAGGGCGCAAGGAGAGCTTTTCCCGGATCGGGCCTTGTCATCCTGGGGCAACGCT GCTGCTGCTGCTGGAGACCCCATAGCTTGCTACACGGACATCCCAAAGATTATTTACGCCTCCAGGACC CACTCGCAACTCACACAGGTCATCAACGAGCTTCGGAACACCTCCTACCGGCCTAAGGTGTGTGTGCTG GGCTCCCGGGAGCAGCTGTGCATCCATCCTGAGGTGAAGAAACAAGAGAGTAACCATCTACAGATCCAC TTGTGCCGTAAGAAGGTGGCAAGTCGCTCCTGTCATTTCTACAACAACGTAGAAGAAAAAAGCCTGGAG CAGGAGCTGGCCAGCCCCATCCTGGACATTGAGGACTTGGTCAAGAGCGGAAGCAAGCACAGGGTGTGC CCTTACTACCTGTCCCGGAACCTGAAGCAGCAAGCCGACATCATATTCATGCCGTACAATTACTTGTTG GATGCCAAGAGCCGCAGAGCACACAACATTGACCTGAAGGGGACAGTCGTGATCTTTGACGAAGCTCAC AACGTGGAGAAGATGTGTGAAGAATCGGCATCCTTTGACCTGACTCCCCATGACCTGGCTTCAGGACTG GACGTCATAGACCAGGTGCTGGAGGAGCAGACCAAGGCAGCGCAGCAGGGTGAGCCCCACCCGGAGTTC AGCGCGGACTCCCCCAGCCCAGGGCTGAACATGGAGCTGGAAGACATTGCAAAGCTGAAGATGATCCTG CTGCGCCTGGAGGGGGCCATCGATGCTGTTGAGCTGCCTGGAGACGACAGCGGTGTCACCAAGCCAGGG AGCTACATCTTTGAGCTGTTTGCTGAAGCCCAGATCACGTTTCAGACCAAGGGCTGCATCCTGGACTCG CTGGACCAGATCATCCAGCACCTGGCAGGACGTGCTGGAGTGTTCACCAACACGGCCGGACTGCAGAAG CTGGCGGACATTATCCAGATTGTGTTCAGTGTGGACCCCTCCGAGGGCAGCCCTGGTTCCCCAGCAGGG CTGGGGGCCTTACAGTCCTATAAGGTGCACATCCATCCTGATGCTGGTCACCGGAGGACGGCTCAGCGG TCTGATGCCTGGAGCACCACTGCAGCCAGAAAGCGAGGGAAGGTGCTGAGCTACTGGTGCTTCAGTCCC GGCCACAGCATGCACGAGCTGGTCCGCCAGGGCGTCCGCTCCCTCATCCTTACCAGCGGCACGCTGGCC CCGGTGTCCTCCTTTGCTCTGGAGATGCAGATCCCTTTCCCAGTCTGCCTGGAGAACCCACACATCATC GACAAGCACCAGATCTGGGTGGGGGTCGTCCCCAGAGGCCCCGATGGAGCCCAGTTGAGCTCCGCGTTT GACAGACGGTTTTCCGAGGAGTGCTTATCCTCCCTGGGGAAGGCTCTGGGCAACATCGCCCGCGTGGTG CCCTATGGGCTCCTGATCTTCTTCCCTTCCTATCCTGTCATGGAGAAGAGCCTGGAGTTCTGGCGGGCC CGCGACTTGGCCAGGAAGATGGAGGCGCTGAAGCCGCTGTTTGTGGAGCCCAGGAGCAAAGGCAGCTTC TCCGAGACCATCAGTGCTTACTATGCAAGGGTTGCCGCCCCTGGGTCCACCGGCGCCACCTTCCTGGCG GTCTGCCGGGGCAAGGCCAGCGAGGGGCTGGACTTCTCAGACACGAATGGCCGTGGTGTGATTGTCACG GGCCTCCCGTACCCCCCACGCATGGACCCCCGGGTTGTCCTCAAGATGCAGTTCCTGGATGAGATGAAG GGCCAGGGTGGGGCTGGGGGCCAGTTCCTCTCTGGGCAGGAGTGGTACCGGCAGCAGGCGTCCAGGGCT GTGAACCAGGCCATCGGGCGAGTGATCCGGCACCGCCAGGACTACGGAGCTGTCTTCCTCTGTGACCAC AGGTTCGCCTTTGCCGACGCAAGAGCCCAACTGCCCTCCTGGGTGCGTCCCCACGTCAGGGTGTATGAC AACTTTGGCCATGTCATCCGAGACGTGGCCCAGTTCTTCCGTGTTGCCGAGCGAACTATGCCAGCGCCG GCCCCCCGGGCTACAGCACCCAGTGTGCGTGGAGAAGATGCTGTCAGCGAGGCCAAGTCGCCTGGCCCC TTCTTCTCCACCAGGAAAGCTAAGAGTCTGGACCTGCATGTCCCCAGCCTGAAGCAGAGGTCCTCAGGG TCACCAGCTGCCGGGGACCCCGAGAGTAGCCTGTGTGTGGAGTATGAGCAGGAGCCAGTTCCTGCCCGG CAGAGGCCCAGGGGGCTGCTGGCCGCCCTGGAGCACAGCGAACAGCGGGCGGGGAGCCCTGGCGAGGAG CAGGCCCACAGCTGCTCCACCCTGTCCCTCCTGTCTGAGAAGAGGCCGGCAGAAGAACCGCGAGGAGGG AGGAAGAAGATCCGGCTGGTCAGCCACCCGGAGGAGCCCGTGGCTGGTGCACAGACGGACAGGGCCAAG CTCTTCATGGTGGCCGTGAAGCAGGAGTTGAGCCAAGCCAACTTTGCCACCTTCACCCAGGCCCTGCAG GACTACAAGGGTTCCGATGACTTCGCCGCCCTGGCCGCCTGTCTCGGCCCCCTCTTTGCTGAGGACCCC AAGAAGCACAACCTGCTCCAAGGCTTCTACCAGTTTGTGCGGCCCCACCATAAGCAGCAGTTTGAGGAG GTCTGTATCCAGCTGACAGGACGAGGCTGTGGCTATCGGCCTGAGCACAGCATTCCCCGAAGGCAGCGG GCACAGCCGGTCCTGGACCCCACTGGAAGAACGGCGCCGGATCCCAAGCTGACCGTGTCCACGGCTGCA GCCCAGCAGCTGGACCCCCAAGAGCACCTGAACCAGGGCAGGCCCCACCTGTCGCCCAGGCCACCCCCA ACAGGAGACCCTGGCAGCCAACCACAGTGGGGGTCTGGAGTGCCCAGAGCAGGGAAGCAGGGCCAGCAC GCCGTGAGCGCCTACCTGGCTGATGCCCGCAGGGCCCTGGGGTCCGCGGGCTGTAGCCAACTCTTGGCA GCGCTGACAGCCTATAAGCAAGACGACGACCTCGACAAGGTGCTGGCTGTGTTGGCCGCCCTGACCACT GCAAAGCCAGAGGACTTCCCCCTGCTGCACAGGTTCAGCATGTTTGTGCGTCCACACCACAAGCAGCGC TTCTCACAGACGTGCACAGACCTGACCGGCCGGCCCTACCCGGGCATGGAGCCACCGGGACCCCAGGAG GAGAGGCTTGCCGTGCCTCCTGTGCTTACCCACAGGGCTCCCCAACCAGGCCCCTCACGGTCCGAGAAG ACCGGGAAGACCCAGAGCAAGATCTCGTCCTTCCTTAGACAGAGGCCAGCAGGGACTGTGGGGGCGGGC GGTGAGGATGCAGGTCCCAGCCAGTCCTCAGGACCTCCCCACGGGCCTGCAGCATCTGAGTGGGGTGAG CCTCATGGGAGAGACATCGCTGGGCAGCAGGCCACGGGAGCTCCGGGCGGGCCCCTCTCAGCAGGCTGT GTGTGCCAGGGCTGTGGGGCAGAGGACGTGGTGCCCTTCCAGTGCCCTGCCTGTGACTTCCAGCGCTGC CAAGCCTGCTGGCAACGGCACCTTCAGGCCTCTAGGATGTGCCCAGCCTGCCACACCGCCTCCAGGAAG CAGAGCGTCATGCAGGTCTTCTGGCCAGAGCCCCAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG240100
Blue=ORF Red=Cloning site Green=Tag(s) MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESPTGTGKTLCLLCTTLAWREHLRDGISA RKIAERAQGELFPDRALSSWGNAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKVCVL GSREQLCIHPEVKKQESNHLQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVC PYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGL DVIDQVLEEQTKAAQQGEPHPEFSADSPSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPG SYIFELFAEAQITFQTKGCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGSPGSPAG LGALQSYKVHIHPDAGHRRTAQRSDAWSTTAARKRGKVLSYWCFSPGHSMHELVRQGVRSLILTSGTLA PVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNIARVV PYGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLA VCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRA VNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAP APRATAPSVRGEDAVSEAKSPGPFFSTRKAKSLDLHVPSLKQRSSGSPAAGDPESSLCVEYEQEPVPAR QRPRGLLAALEHSEQRAGSPGEEQAHSCSTLSLLSEKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAK LFMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHNLLQGFYQFVRPHHKQQFEE VCIQLTGRGCGYRPEHSIPRRQRAQPVLDPTGRTAPDPKLTVSTAAAQQLDPQEHLNQGRPHLSPRPPP TGDPGSQPQWGSGVPRAGKQGQHAVSAYLADARRALGSAGCSQLLAALTAYKQDDDLDKVLAVLAALTT AKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMEPPGPQEERLAVPPVLTHRAPQPGPSRSEK TGKTQSKISSFLRQRPAGTVGAGGEDAGPSQSSGPPHGPAASEWGEPHGRDIAGQQATGAPGGPLSAGC VCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVMQVFWPEPQ TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001283009 |
ORF Size | 3900 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001283009.2 |
RefSeq Size | 5140 bp |
RefSeq ORF | 3903 bp |
Locus ID | 51750 |
UniProt ID | Q9NZ71 |
Protein Families | Druggable Genome |
MW | 142.4 kDa |
Gene Summary | This gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013] |
Documents
Product Manuals |
FAQs |
SDS |