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SIN3B (NM_001297595) Human Tagged ORF Clone
CAT＃: RG239993
- TrueORF®
SIN3B (tGFP-tagged) - Human SIN3 transcription regulator family member B (SIN3B), transcript variant 2
ORF Plasmid: DDK
"NM_001297595" in other vectors (2)
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CNY 11,690.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239993 representing NM_001297595.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGCACGCTGGCGGTGGCAGCGGTGGCAGCGGTGCCGGCGGCCCCGCGGGCCGGGGGCTGAGCGGC GCCCGCTGGGGTCGCTCGGGCTCCGCAGGCCACGAGAAGCTGCCGGTGCACGTAGAAGACGCCCTCACC TATCTGGACCAGGTGAAGATCCGCTTTGGCAGCGACCCTGCCACCTACAACGGCTTCCTGGAGATCATG AAGGAGTTCAAAAGCCAGAGCATCGATACTCCTGGAGTCATCAGACGTGTCTCGCAGCTCTTCCACGAG CACCCTGACCTCATTGTTGGATTCAACGCTTTTCTTCCCCTCGGATATAGAATAGACATTCCCAAGAAT GGCAAGTTAAACATACAGTCGCCTCTGACAAGCCAGGAGAATTCGCACAACCACGGGGACGGTGCAGAG GACTTCAAGCAGCAGGTGCCGTATAAAGAGGACAAACCCCAGGTGCCCCTGGAGTCCGATTCCGTGGAA TTCAACAACGCCATCAGCTATGTGAATAAGATTAAAACCCGCTTCCTAGACCACCCAGAAATCTACAGG TCATTCCTGGAGATCCTGCACACGTACCAGAAGGAGCAGCTGAACACGAGGGGCCGGCCATTCCGAGGC ATGTCTGAAGAGGAGGTGTTCACCGAGGTGGCCAACCTCTTCCGGGGCCAGGAGGACCTGCTCTCAGAG TTTGGACAGTTCCTGCCCGAAGCCAAGCGGTCTCTGTTCACAGGAAACGGGCCGTGCGAGATGCACAGC GTGCAGAAGAACGAGCACGACAAGACCCCGGAGCACAGCAGGAAGCGCTCCCGGCCCTCGCTCCTCCGC CCCGTGTCTGCACCCGCCAAGAAAAAAATGAAACTTCGTGGTACCAAAGACCTGTCCATCGCTGCAGTG GGGAAGTACGGGACTCTGCAGGAATTTTCTTTCTTTGACAAGGTCCGCCGGGTGCTGAAGAGCCAGGAG GTGTATGAAAACTTCCTCCGCTGCATCGCACTCTTCAACCAGGAGCTGGTGTCTGGCTCTGAGCTCCTG CAGCTCGTCAGCCCATTTCTGGGGAAATTTCCAGAACTCTTTGCACAGTTCAAGTCCTTCCTGGGGGTA AAAGAGCTGTCCTTCGCGCCACCCATGAGCGACAGATCCGGGGACGGGATAAGCCGGGAAATTGATTAT GCATCCTGCAAGCGCATAGGATCCAGCTACCGGGCACTCCCCAAAACCTACCAGCAGCCCAAGTGCAGT GGGAGGACAGCCATCTGCAAGGAGGTACTGAACGACACCTGGGTCTCCTTCCCTTCCTGGTCTGAGGAC TCCACGTTCGTCAGCTCCAAGAAGACACCGTACGAGGAGCAGCTTCACCGCTGTGAGGACGAGCGCTTC GAGTTAGACGTTGTCCTGGAGACGAACCTGGCCACAATCCGTGTGTTGGAAAGTGTGCAGAAGAAGCTG TCTCGGATGGCGCCGGAAGACCAGGAGAAGTTCCGGCTGGACGACTCCCTGGGAGGCACGTCGGAGGTG ATCCAGCGCCGTGCCATTTATCGCATCTATGGCGACAAGGCCCCGGAGATCATCGAGAGCCTCAAGAAG AACCCTGTCACCGCTGTCCCCGTTGTCCTGAAAAGACTGAAGGCCAAGGAAGAGGAGTGGCGGGAGGCC CAGCAGGGCTTCAACAAGATCTGGCGGGAGCAGTATGAGAAGGCGTACCTCAAGTCCCTTGACCACCAG GCTGTGAACTTCAAGCAGAACGACACCAAGGCCCTGCGCTCCAAGAGCTTGCTCAACGAGATCGAGAGC GTCTACGACGAGCACCAGGAGCAGCACTCGGAGGGCCGCAGTGCCCCCTCTAGCGAGCCGCACCTCATC TTTGTGTACGAGGACCGGCAGATCCTGGAGGACGCAGCAGCGCTCATCAGCTACTACGTGAAGCGGCAG CCGGCCATCCAGAAGGAGGACCAGGGCACCATCCACCAGCTGCTGCACCAGTTCGTGCCCAGCCTCTTC TTCTCTCAGCAGCTGGACCTGGGCGCCTCCGAGGAGTCAGCTGATGAGGACCGGGACAGCCCCCAGGGG CAGACCACAGACCCCAGTGAGCGGAAGAAGCCGGCGCCAGGACCCCACAGTAGCCCCCCAGAGGAGAAG GGGGCCTTCGGGGATGCCCCGGCCACTGAGCAGCCACCCCTGCCGCCCCCAGCCCCGCACAAGCCCCTG GACGATGTCTACAGCCTATTTTTTGCCAACAACAACTGGTACTTCTTCCTGCGCCTGCACCAGACCCTG TGCTCCAGGCTGCTGAAGATCTACCGCCAGGCGCAGAAGCAGCTTCTGGAGTATCGGACCGAGAAGGAG CGGGAGAAGCTGCTGTGTGAGGGCCGCAGGGAGAAGGGCAGCGACCCCGCCATGGAGCTGCGGCTGAAG CAGCCCAGTGAAGTGGAGCTGGAGGAGTACTACCCGGCCTTCCTGGACATGGTGCGGAGCCTGCTGGAG GGCAGCATCGACCCCACGCAGTACGAGGACACCCTACGCGAGATGTTCACCATCCATGCCTACGTGGGC TTCACCATGGACAAGCTGGTGCAGAACATTGCGCGGCAGCTGCACCACCTCGTGAGCGATGACGTCTGC CTGAAGGTGGTGGAGCTCTACCTGAACGAGAAGAAGCGGGGTGCCGCTGGTGGGAACCTGTCCTCCCGC TGCGTCCGCGCTGCTAGGGAGACCAGCTACCAGTGGAAGGCTGAGCGCTGCATGGCCGACGAGAACTGC TTCAAGGTGATGTTCCTGCAGCGCAAAGGGCAGGTGATCATGACCATCGAGCTCCTGGACACCGAGGAG GCCCAGACGGAGGACCCTGTGGAGGTCCAGCACCTGGCTCGGTACGTGGAGCAGTATGTGGGGACCGAG GGCGCGTCCAGCTCGCCCACTGAGGGCTTCCTCCTGAAACCTGTGTTCCTGCAGAGGAACCTCAAGAAG TTCCGCCGCCGGTGGCAGAGCGAGCAGGCGCGGGCCCTGCGCGGTGAGGCCAGGAGCTCCTGGAAGCGG CTGGTGGGCGTGGAGAGCGCCTGCGACGTGGACTGCCGCTTCAAGCTCAGCACTCACAAGATGGTGTTC ATCGTGAACTCCGAGGACTACATGTACCGTCGCGGGACCCTCTGCCGGGCCAAGCAGGTGCAGCCCCTG GTCCTGCTCCGCCACCACCAGCACTTTGAGGAGTGGCACAGCCGCTGGCTGGAGGACAATGTGACGGTG GAGGCGGCTAGCCTGGTGCAGGACTGGCTGATGGGTGAGGAGGACGAGGACATGGTACCCTGCAAGACG CTGTGTGAGACAGTGCACGTGCACGGCCTGCCCGTGACCCGCTACCGCGTGCAGTACAGCCGCCGCCCG GCCTCGCCC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239993
Blue=ORF Red=Cloning site Green=Tag(s) MAHAGGGSGGSGAGGPAGRGLSGARWGRSGSAGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLEIM KEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAE DFKQQVPYKEDKPQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTRGRPFRG MSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLR PVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELL QLVSPFLGKFPELFAQFKSFLGVKELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCS GRTAICKEVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKL SRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEEWREA QQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSEPHLI FVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQG QTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTL CSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLE GSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGNLSSR CVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGTE GASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTHKMVF IVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMVPCKT LCETVHVHGLPVTRYRVQYSRRPASP TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001297595 |
| ORF Size | 3390 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001297595.2 |
| RefSeq Size | 5053 bp |
| RefSeq ORF | 3393 bp |
| Locus ID | 23309 |
| UniProt ID | O75182 |
| MW | 129.8 kDa |
| Gene Summary | Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.[UniProtKB/Swiss-Prot Function] |
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