NBR1 (NM_001291572) Human Tagged ORF Clone
CAT#: RG239654
- TrueORF®
NBR1 (tGFP-tagged) - Human neighbor of BRCA1 gene 1 (NBR1), transcript variant 5
ORF Plasmid: DDK
"NM_001291572" in other vectors (2)
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CNY 7,510.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | 1A1-3B; IAI3B; M17S2; MIG19 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG239654 representing NM_001291572.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAACCACAGGTTACTCTAAATGTGACTTTTAAAAATGAAATTCAAAGCTTTCTGGTTTCTGATCCA GAAAATACAACTTGGGCTGATATCGAAGCTATGGTATCCATCAACAGTCAAGGAGAATATGAAGAAGCG CTTAAGATGGCAGTTAAACAGGGAAACCAACTGCAGATGCAAGTCCACGAAGGGCACCATGTCGTTGAT GAAGCCCCACCCCCAGTTGTAGGAGCAAAACGACTAGCTGCCAGGGCAGGGAAGAAGCCACTTGCACAT TACTCTTCACTGGTGAGAGTCTTGGGATCAGACATGAAGACCCCAGAGGATCCTGCAGTGCAGTCGTTT CCACTTGTTCCATGTGACACAGACCAGCCTCAAGACAAGCCCCCAGACTGGTTCACAAGCTACCTGGAG ACGTTCAGAGAACAAGTGGTTAACGAAACGGTTGAGAAGCTTGAACAGAAATTACATGAAAAGCTTGTC CTCCAGAACCCATCCTTGGGTTCTTGTCCCTCAGAAGTCTCAATGCCTACTTCAGAAGAAACATTGTTT TTGCCAGAAAACCAGTTCAGCTGGCATATTGCTTGCAACAACTGCCAAAGAAGGATTGTTGGTGTCCGC TACCAGTGTAGCCTATGCCCATCCTACAATATCTGTGAAGATTGTGAAGCAGGGCCATATGGCCATGAC ACTAACCACGTCCTGCTGAAGTTGCGGAGACCTGTTGTGGGCTCCTCTGAACCGTTCTGTCACTCAAAG TACTCTACTCCTCGTCTTCCTGCTGCTCTGGAACAAGTCAGGCTCCAGAAACAGGTTGATAAGAACTTT CTTAAAGCAGAAAAGCAAAGGTTGCGAGCTGAGAAGAAACAACGTAAAGCAGAGGTCAAGGAACTTAAA AAGCAGCTTAAACTCCATAGGAAAATTCACCTGTGGAATTCAATCCATGGACTCCAGAGCCCCAAGTCT CCTTTAGGCCGACCTGAGAGCTTGCTCCAGTCTAATACCCTGATGCTCCCTTTGCAGCCCTGTACCTCC GTTATGCCAATGCTCAGTGCAGCATTTGTGGATGAGAATTTGCCTGATGGGACTCACCTTCAGCCAGGA ACCAAGTTTATCAAACACTGGAGGATGAAAAATACAGGAAATGTAAAGTGGAGTGCAGACACAAAGCTC AAGTTCATGTGGGGAAACCTGACTTTGGCTTCCACAGAAAAGAAGGATGTTTTGGTTCCCTGCCTCAAG GCCGGCCATGTGGGAGTTGTATCTGTGGAGTTCATTGCCCCAGCCTTGGAGGGAACGTATACTTCCCAT TGGCGTCTTTCTCACAAAGGCCAGCAATTTGGGCCTCGGGTCTGGTGCAGTATCATAGTAGATCCTTTC CCCTCCGAAGAGAGCCCTGATAACATTGAAAAGGGCATGATCAGCTCAAGCAAAACTGATGATCTCACC TGCCAGCAAGAGGAAACTTTTCTTCTGGCTAAAGAAGAAAGACAGCTTGGTGAAGTGACTGAGCAGACA GAAGGGACAGCAGCCTGCATCCCACAGAAGGCAAAAAATGTTGCCAGTGAGAGGGAGCTCTACATCCCA TCTGTGGATCTTCTGACTGCCCAGGACCTGCTGTCCTTTGAGCTGTTGGATATAAACATTGTTCAAGAG TTGGAGAGAGTGCCCCACAACACCCCTGTGGATGTGACTCCCTGCATGTCTCCTCTGCCACATGACAGT CCTTTAATAGAGAAGCCAGGCTTGGGGCAGATAGAGGAAGAGAATGAAGGGGCAGGATTTAAAGCACTT CCTGATTCTATGGTGTCAGTAAAGAGGAAGGCTGAGAACATTGCTTCTGTGGAGGAAGCAGAAGAAGAC CTGAGTGGGACCCAGTTTGTGTGTGAGACAGTAATCCGATCCCTTACCTTGGATGCTGCCCCAGACCAC AACCCTCCTTGCAGACAGAAGTCCTTGCAGATGACATTTGCCTTGCCTGAAGGACCACTTGGAAATGAG AAGGAGGAGATTATCCATATCGCTGAGGAAGAAGCTGTCATGGAGGAGGAGGAGGATGAGGAGGATGAG GAGGAGGAGGATGAGCTCAAAGATGAAGTTCAAAGTCAGTCCTCTGCTTCCTCAGAGGATTACATCATC ATCCTGCCTGAGTGCTTTGATACCAGCCGCCCCCTGGGGGATTCTATGTACAGCTCTGCGCTCTCACAG CCAGGCCTGGAGCGAGGTGCTGAAGGCAAGCCTGGGGTTGAGGCTGGGCAGGAACCAGCTGAGGCTGGG GAAAGACTCCCTGGAGGGGAGAACCAGCCACAGGAGCACAGCATAAGTGACATCCTCACGACCTCACAG ACTCTGGAAACAGTGCCCCTAATCCCAGAGGTAGTGGAGCTTCCACCGTCACTGCCCAGGAGCTCTCCT TGTGTACATCATCATGGTTCCCCAGGAGTGGATTTACCAGTTACCATACCAGAAGTTTCTTCAGTCCCT GATCAGATCAGAGGAGCCAATAATTTC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239654
Blue=ORF Red=Cloning site Green=Tag(s) MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVSINSQGEYEEALKMAVKQGNQLQMQVHEGHHVVD EAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPLVPCDTDQPQDKPPDWFTSYLE TFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVR YQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYSTPRLPAALEQVRLQKQVDKNF LKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPLGRPESLLQSNTLMLPLQPCTS VMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVLVPCLK AGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPSEESPDNIEKGMISSSKTDDLT CQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSVDLLTAQDLLSFELLDINIVQE LERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPDSMVSVKRKAENIASVEEAEED LSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKEEIIHIAEEEAVMEEEEDEEDE EEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPGLERGAEGKPGVEAGQEPAEAG ERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCVHHHGSPGVDLPVTIPEVSSVP DQIRGANNF TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001291572 |
ORF Size | 2511 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001291572.2 |
RefSeq Size | 4647 bp |
RefSeq ORF | 2514 bp |
Locus ID | 4077 |
UniProt ID | Q14596 |
Protein Families | Druggable Genome |
MW | 93.4 kDa |
Gene Summary | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Documents
Product Manuals |
FAQs |
SDS |