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SIN3B (NM_001297597) Human Tagged ORF Clone
CAT＃: RG239409
- TrueORF®
SIN3B (tGFP-tagged) - Human SIN3 transcription regulator family member B (SIN3B), transcript variant 3
ORF Plasmid: DDK
"NM_001297597" in other vectors (2)
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CNY 6,180.00
货期*
2周
规格
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经常一起买 (5)
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG239409 representing NM_001297597.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCAGCGTCATTCACGGCATTTCCTCTTGGTGCAGGTACTGAACGACACCTGGGTCTCCTTCCCTTCC TGGTCTGAGGACTCCACGTTCGTCAGCTCCAAGAAGACACCGTACGAGGAGCAGCTTCACCGCTGTGAG GACGAGCGCTTCGAGTTAGACGTTGTCCTGGAGACGAACCTGGCCACAATCCGTGTGTTGGAAAGTGTG CAGAAGAAGCTGTCTCGGATGGCGCCGGAAGACCAGGAGAAGTTCCGGCTGGACGACTCCCTGGGAGGC ACGTCGGAGGTGATCCAGCGCCGTGCCATTTATCGCATCTATGGCGACAAGGCCCCGGAGATCATCGAG AGCCTCAAGAAGAACCCTGTCACCGCTGTCCCCGTTGTCCTGAAAAGACTGAAGGCCAAGGAAGAGGAG TGGCGGGAGGCCCAGCAGGGCTTCAACAAGATCTGGCGGGAGCAGTATGAGAAGGCGTACCTCAAGTCC CTTGACCACCAGGCTGTGAACTTCAAGCAGAACGACACCAAGGCCCTGCGCTCCAAGAGCTTGCTCAAC GAGATCGAGAGCGTCTACGACGAGCACCAGGAGCAGCACTCGGAGGGCCGCAGTGCCCCCTCTAGCGAG CCGCACCTCATCTTTGTGTACGAGGACCGGCAGATCCTGGAGGACGCAGCAGCGCTCATCAGCTACTAC GTGAAGCGGCAGCCGGCCATCCAGAAGGAGGACCAGGGCACCATCCACCAGCTGCTGCACCAGTTCGTG CCCAGCCTCTTCTTCTCTCAGCAGCTGGACCTGGGCGCCTCCGAGGAGTCAGCTGATGAGGACCGGGAC AGCCCCCAGGGGCAGACCACAGACCCCAGTGAGCGGAAGAAGCCGGCGCCAGGACCCCACAGTAGCCCC CCAGAGGAGAAGGGGGCCTTCGGGGATGCCCCGGCCACTGAGCAGCCACCCCTGCCGCCCCCAGCCCCG CACAAGCCCCTGGACGATGTCTACAGCCTATTTTTTGCCAACAACAACTGGTACTTCTTCCTGCGCCTG CACCAGACCCTGTGCTCCAGGCTGCTGAAGATCTACCGCCAGGCGCAGAAGCAGCTTCTGGAGTATCGG ACCGAGAAGGAGCGGGAGAAGCTGCTGTGTGAGGGCCGCAGGGAGAAGGGCAGCGACCCCGCCATGGAG CTGCGGCTGAAGCAGCCCAGTGAAGTGGAGCTGGAGGAGTACTACCCGGCCTTCCTGGACATGGTGCGG AGCCTGCTGGAGGGCAGCATCGACCCCACGCAGTACGAGGACACCCTACGCGAGATGTTCACCATCCAT GCCTACGTGGGCTTCACCATGGACAAGCTGGTGCAGAACATTGCGCGGCAGCTGCACCACCTCGTGAGC GATGACGTCTGCCTGAAGGTGGTGGAGCTCTACCTGAACGAGAAGAAGCGGGGTGCCGCTGGTGGGAAC CTGTCCTCCCGCTGCGTCCGCGCTGCTAGGGAGACCAGCTACCAGTGGAAGGCTGAGCGCTGCATGGCC GACGAGAACTGCTTCAAGGTGATGTTCCTGCAGCGCAAAGGGCAGGTGATCATGACCATCGAGCTCCTG GACACCGAGGAGGCCCAGACGGAGGACCCTGTGGAGGTCCAGCACCTGGCTCGGTACGTGGAGCAGTAT GTGGGGACCGAGGGCGCGTCCAGCTCGCCCACTGAGGGCTTCCTCCTGAAACCTGTGTTCCTGCAGAGG AACCTCAAGAAGTTCCGCCGCCGGTGGCAGAGCGAGCAGGCGCGGGCCCTGCGCGGTGAGGCCAGGAGC TCCTGGAAGCGGCTGGTGGGCGTGGAGAGCGCCTGCGACGTGGACTGCCGCTTCAAGCTCAGCACTCAC AAGATGGTGTTCATCGTGAACTCCGAGGACTACATGTACCGTCGCGGGACCCTCTGCCGGGCCAAGCAG GTGCAGCCCCTGGTCCTGCTCCGCCACCACCAGCACTTTGAGGAGTGGCACAGCCGCTGGCTGGAGGAC AATGTGACGGTGGAGGCGGCTAGCCTGGTGCAGGACTGGCTGATGGGTGAGGAGGACGAGGACATGGTA CCCTGCAAGACGCTGTGTGAGACAGTGCACGTGCACGGCCTGCCCGTGACCCGCTACCGCGTGCAGTAC AGCCGCCGCCCGGCCTCGCCC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239409
Blue=ORF Red=Cloning site Green=Tag(s) MQRHSRHFLLVQVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESV QKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVTAVPVVLKRLKAKEEE WREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSEGRSAPSSE PHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIHQLLHQFVPSLFFSQQLDLGASEESADEDRD SPQGQTTDPSERKKPAPGPHSSPPEEKGAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRL HQTLCSRLLKIYRQAQKQLLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVR SLLEGSIDPTQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQHLARYVEQY VGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRLVGVESACDVDCRFKLSTH KMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSRWLEDNVTVEAASLVQDWLMGEEDEDMV PCKTLCETVHVHGLPVTRYRVQYSRRPASP TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001297597 |
| ORF Size | 2160 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001297597.1, NP_001284526.1 |
| RefSeq Size | 4159 bp |
| RefSeq ORF | 2163 bp |
| Locus ID | 23309 |
| UniProt ID | O75182 |
| MW | 84.1 kDa |
| Gene Summary | Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.[UniProtKB/Swiss-Prot Function] |
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