EXDL1 (EXD1) (NM_001286441) Human Tagged ORF Clone
CAT#: RG238940
- TrueORF®
EXD1 (tGFP-tagged) - Human exonuclease 3'-5' domain containing 1 (EXD1), transcript variant 1
ORF Plasmid: DDK
"NM_001286441" in other vectors (2)
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CNY 4,940.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | EXDL1 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG238940 representing NM_001286441.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGACCCCAGCAGTGACTACCATTTCCTCAGCCAGATTTTGTGGAAGAGGGTGAAACTCACATTGGTC TGTGGTGTCTTCGAGGGTGTGCTTCAGCATGTTGACCCTAATAAGATTGTTGTCCTGAAGAAAGTGAAG AATGTGGAGACAGGTCGAAGTGTCCCAGGAGTGAAGTTGTTTTTTGGGCATGAGATTGTGAATGTGGAA CTACTAGATGAAGTGGAACAAGGCTCAGTGAGAGCAAAAGCATCTTCTGTTAGTCTACATGCAGAAAGA ACCTGGATGGAGAAAATGAAAGTTGAAGACCTAAATGTATGTGAGCCTGCTTCTCCTGCCCCTGAAGCA CCAGCTACCTCTCTGCTGAATGACCTCAAGTACAGCCCATCAGAGGAAGAGGAGGTGACATACACAGTC ATTAATCAATTCCAGCAGAAGTTTGGTGCTGCGATACTCCATATCAAGAAGCAGAATGTCCTGAGTGTG GCAGCAGAAGGAGCGAATGTATGTCGCCATGGCAAACTGTGCTGGCTGCAGGTGGCCACAAATTGCCGA GTTTACTTATTTGACATTTTCCTTCTGGGAAGTCGAGCTTTCCACAATGGACTTCAGATGATACTAGAA GACAAGAGAATTTTGAAGGTTATCCATGATTGTCGTTGGCTTTCTGATTGCCTCTCTCATCAGTATGGA ATTTTGCTGAATAATGTCTTTGACACACAGGTAGCAGATGTACTTCAGTTTTCCATGGAAACGGGTGGC TATCTTCCAAACTGCATCACTACTTTGCAGGAGAGTTTAATCAAACACCTTCAAGTAGCCCCTAAATAT CTCTCCTTTCTAGAAAAGAGACAAAAACTAATTCAGGAAAATCCAGAAGTATGGTTCATCCGACCTGTT TCACCCTCTTTACTGAAAATTTTGGCCCTGGAAGCTACCTACCTGTTACCCCTTCGCTTGGCACTCCTA GATGAGATGATGTCTGACCTAACCACCCTGGTGGATGGTTACCTAAACACGTATCGCGAAGGGTCTGCA GACCGGCTTGGAGGCACTGAGCCTACATGTATGGAGCTGCCAGAGGAACTGCTTCAACTCAAGGACTTC CAGAAGCAGCGCAGGGAGAAAGCTGCAAGAGAATATAGGGTGAATGCACAGGGACTCCTGATAAGGACA GTGCTACAGCCAAAGAAATTAGTGACAGAGACAGCAGGGAAAGAGGAGAAAGTCAAAGGCTTCTTATTT GGTAAAAATTTTAGGATAGATAAAGCTCCAAGTTTTACATCTCAAGACTTTCACGGGGATGTGAATTTA CTGAAAGAAGAATCTTTGAATAAACAAGCTACAAATCCTCAACATCTACCTCCCACAGAGGAAGGGGAA ACCAGTGAGGATTCCAGTAACAAACTCATTTGCACAAAGTCAAAGGGGTCAGAGGACCAGAGAATAACT CAGAAAGAACACTTTATGACACCCAAACATGAGTTTCAGGCAAGTTTATCTTTGAAAGAGGAGACAGAA CAGTTATTGATGGTGGAAAACAAGGAAGATTTAAAATGCACAAAACAGGCTGTTTCAATGTCTTCCTTT CCTCAGGAAACCAGAGTGTCTCCAAGTGACACTTTTTATCCTATCAGAAAGACTGTGGTTTCCACACTC CCTCCCTGTCCAGCCTTGGAGAAGATCGATTCCTGGATAAGTCCTTTTCTAAATCTGCCC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG238940
Blue=ORF Red=Cloning site Green=Tag(s) MDPSSDYHFLSQILWKRVKLTLVCGVFEGVLQHVDPNKIVVLKKVKNVETGRSVPGVKLFFGHEIVNVE LLDEVEQGSVRAKASSVSLHAERTWMEKMKVEDLNVCEPASPAPEAPATSLLNDLKYSPSEEEEVTYTV INQFQQKFGAAILHIKKQNVLSVAAEGANVCRHGKLCWLQVATNCRVYLFDIFLLGSRAFHNGLQMILE DKRILKVIHDCRWLSDCLSHQYGILLNNVFDTQVADVLQFSMETGGYLPNCITTLQESLIKHLQVAPKY LSFLEKRQKLIQENPEVWFIRPVSPSLLKILALEATYLLPLRLALLDEMMSDLTTLVDGYLNTYREGSA DRLGGTEPTCMELPEELLQLKDFQKQRREKAAREYRVNAQGLLIRTVLQPKKLVTETAGKEEKVKGFLF GKNFRIDKAPSFTSQDFHGDVNLLKEESLNKQATNPQHLPPTEEGETSEDSSNKLICTKSKGSEDQRIT QKEHFMTPKHEFQASLSLKEETEQLLMVENKEDLKCTKQAVSMSSFPQETRVSPSDTFYPIRKTVVSTL PPCPALEKIDSWISPFLNLP TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001286441 |
ORF Size | 1716 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001286441.2 |
RefSeq Size | 3264 bp |
RefSeq ORF | 1719 bp |
Locus ID | 161829 |
UniProt ID | Q8NHP7 |
MW | 65.3 kDa |
Gene Summary | RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |