COMMD5 (NM_001287237) Human Tagged ORF Clone
CAT#: RG236704
- TrueORF®
COMMD5 (tGFP-tagged) - Human COMM domain containing 5 (COMMD5), transcript variant 4
ORF Plasmid: DDK
"NM_001287237" in other vectors (2)
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CNY 4,370.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | HCARG; HT002 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG236704 representing NM_001287237.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTCTGCTGTGGGGGCTGCAACTCCATACCTGCATCATCCTGGTGATAGTCACAGTGGCCGAGTGAGT TTCTTGGGGGCCCAGCTTCCTCCAGAGGTGGCAGCAATGGCCCGGCTACTAGGGGACCTAGACAGGAGC ACGTTCAGAAAGTTGCTGAAGTTTGTGGTCAGCAGCCTGCAGGGGGAGGACTGCCGAGAGGCTGTGCAG CGTCTTGGGGTCAGCGCCAACCTGCCGGAGGAGCAGCTGGGTGCCCTGCTGGCAGGCATGCACACACTG CTCCAGCAGGCCCTCCGTCTGCCCCCCACCAGCCTGAAGCCTGACACCTTCAGGGACCAGCTCCAGGAG CTCTGCATCCCCCAAGACCTGGTCGGGGACTTGGCCAGCGTGGTATTTGGGAGCCAGCGGCCCCTCCTT GATTCTGTGGCCCAGCAGCAGGGGGCCTGGCTGCCGCATGTTGCTGACTTTCGGTGGCGGGTGGATGTA GCAATCTCCACCAGTGCCCTGGCTCGCTCCCTGCAGCCGAGCGTCCTGATGCAGCTGAAGCTTTCAGAT GGGTCAGCATACCGCTTTGAGGTCCCCACAGCCAAGTTCCAGGAGCTGCGGTACAGCGTGGCCCTGGTC CTAAAGGAGATGGCAGATCTGGAGAAGAGGTGTGAGCGCAGACTGCAGGAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG236704
Blue=ORF Red=Cloning site Green=Tag(s) MSAVGAATPYLHHPGDSHSGRVSFLGAQLPPEVAAMARLLGDLDRSTFRKLLKFVVSSLQGEDCREAVQ RLGVSANLPEEQLGALLAGMHTLLQQALRLPPTSLKPDTFRDQLQELCIPQDLVGDLASVVFGSQRPLL DSVAQQQGAWLPHVADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAYRFEVPTAKFQELRYSVALV LKEMADLEKRCERRLQD TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001287237 |
ORF Size | 672 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001287237.1, NP_001274166.1 |
RefSeq Size | 1588 bp |
RefSeq ORF | 675 bp |
Locus ID | 28991 |
UniProt ID | Q9GZQ3 |
Protein Families | Druggable Genome |
MW | 24.7 kDa |
Gene Summary | May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis (By similarity). Down-regulates activation of NF-kappa-B (PubMed:15799966).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |