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NBL1 (NM_001204086) Human Tagged ORF Clone
CAT＃: RG236633
- TrueORF®
NBL1 (tGFP-tagged) - Human neuroblastoma 1, DAN family BMP antagonist (NBL1), transcript variant 5
ORF Plasmid: DDK
"NM_001204086" in other vectors (2)
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CNY 4,370.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | D1S1733E; DAN; DAND1; NB; NO3 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG236633 representing NM_001204086.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTGCAGCCTGGCCCTGCAGCAGCTCATTAGCATGGATTTGTTTTGGAGACTGTTTTTCGTTTGCGGG CAGGAGGGTCTGCGGGCTCTGGAGGCCACGGGCATGATGCTTCGGGTCCTGGTGGGGGCTGTCCTCCCT GCCATGCTACTGGCTGCCCCACCACCCATCAACAAGCTGGCACTGTTCCCAGATAAGAGTGCCTGGTGC GAAGCCAAGAACATCACCCAGATCGTGGGCCACAGCGGCTGTGAGGCCAAGTCCATCCAGAACAGGGCG TGCCTAGGACAGTGCTTCAGCTACAGCGTCCCCAACACCTTCCCACAGTCCACAGAGTCCCTGGTTCAC TGTGACTCCTGCATGCCAGCCCAGTCCATGTGGGAGATTGTGACGCTGGAGTGCCCGGGCCACGAGGAG GTGCCCAGGGTGGACAAGCTGGTGGAGAAGATCCTGCACTGTAGCTGCCAGGCCTGCGGCAAGGAGCCT AGTCACGAGGGGCTGAGCGTCTATGTGCAGGGCGAGGACGGGCCGGGATCCCAGCCCGGCACCCACCCT CACCCCCATCCCCACCCCCATCCTGGCGGGCAGACCCCTGAGCCCGAGGACCCCCCTGGGGCCCCCCAC ACAGAGGAAGAGGGGGCTGAGGAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG236633
Blue=ORF Red=Cloning site Green=Tag(s) MCSLALQQLISMDLFWRLFFVCGQEGLRALEATGMMLRVLVGAVLPAMLLAAPPPINKLALFPDKSAWC EAKNITQIVGHSGCEAKSIQNRACLGQCFSYSVPNTFPQSTESLVHCDSCMPAQSMWEIVTLECPGHEE VPRVDKLVEKILHCSCQACGKEPSHEGLSVYVQGEDGPGSQPGTHPHPHPHPHPGGQTPEPEDPPGAPH TEEEGAED TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001204086 |
| ORF Size | 645 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reference Data | |
| RefSeq | NM_001204086.2, NP_001191015.1 |
| RefSeq Size | 2178 bp |
| RefSeq ORF | 648 bp |
| Locus ID | 4681 |
| Protein Families | Secreted Protein |
| MW | 23.7 kDa |
| Gene Summary | This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed. [provided by RefSeq, May 2013] |
Documents
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