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SOCS7 (NM_014598) Human Tagged ORF Clone
CAT＃: RC211558
SOCS7 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 7 (SOCS7)
ORF Plasmid: tGFP
"NM_014598" in other vectors (4)
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CNY 4,328.00
CNY 4,560.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | NAP4; NCKAP4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC211558 representing NM_014598
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCT CGGAACTGCTGTGTCCCCGGCACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGA GCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTGGCGGCTCTGGGGCTCGGGCAGCCGGCGGGG CCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCCCCTCCGCAGC CCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCT GGAGGGCTTGGAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCG GGTCGCGGAGGAGGAGGGGGCGGCCGGCTTCTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCT TCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAGCAGCAGCAGCAGCAGCAGCA ACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCG GCAAGAGGCCTTCTGGAGAGCTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCG GGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACTCAAAGTGCCTTTTCTCCGGTCTCCTTCAGC CCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTGACCTCTCCAC ACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCC TACATCTGTCCTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCC CATGCCCCAGATGCATTTCCCCGGATTGCTCCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCAC AGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCCAGCCTTCGAGAGTTGGAGAA GTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCA CCCACCACACTAGAATGGAGCACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCG CTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATGCACTCCAAGAATGGAAAGTTTCTCTATTTC TTAAGATCCAGGGTTCCAGGACTGCCACCAACTCCTGTCCAGCTGCTCTATCCAGTGTCCCGATTCAGCA ATGTCAAATCCCTCCAGCACCTTTGCAGATTCCGGATACGACAGCTCGTCAGGATAGATCACATCCCAGA TCTCCCACTGCCTAAACCTCTGATCTCTTATATCCGAAAGTTCTACTACTATGATCCTCAGGAAGAGGTA TACCTGTCTCTAAAGGAAGCGCAGCTCATTTCCAAACAGAAGCAAGAGGTGGAACCCTCCACG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC211558 representing NM_014598
Red=Cloning site Green=Tags(s) MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAG PGVKTVGGGCCPCPCPPQPPPPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSP GRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQQQQQQQQPPPPPPPPGPLRPLAGPSRKGSF KIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRTQSAFSPVSFS PLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPP HAPDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDG SFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYF LRSRVPGLPPTPVQLLYPVSRFSNVKSLQHLCRFRIRQLVRIDHIPDLPLPKPLISYIRKFYYYDPQEEV YLSLKEAQLISKQKQEVEPST TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_014598 |
| ORF Size | 1743 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014598.3, NP_055413.1 |
| RefSeq Size | 2162 bp |
| RefSeq ORF | 1938 bp |
| Locus ID | 30837 |
| UniProt ID | O14512 |
| Protein Families | Druggable Genome |
| Protein Pathways | Jak-STAT signaling pathway |
| MW | 62.8 kDa |
| Gene Summary | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211558L3 | Lenti ORF clone of Human suppressor of cytokine signaling 7 (SOCS7), Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC211558L4 | Lenti ORF clone of Human suppressor of cytokine signaling 7 (SOCS7), mGFP tagged |
CNY 6,460.00 |
|
| RG211558 | SOCS7 (tGFP-tagged) - Human suppressor of cytokine signaling 7 (SOCS7) |
CNY 5,040.00 |
|
| SC304138 | SOCS7 (untagged)-Human suppressor of cytokine signaling 7 (SOCS7) |
CNY 9,310.00 |
