United States
Germany
Japan
United Kingdom
China
SREBP2 (SREBF2) (NM_004599) Human Tagged ORF Clone
CAT＃: RC208942
SREBF2 (Myc-DDK-tagged)-Human sterol regulatory element binding transcription factor 2 (SREBF2)
ORF Plasmid: tGFP
"NM_004599" in other vectors (6)
Need custom modification / cloning service?
Get a free quote
CNY 11,920.00
| Cited in 1 publication. |
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | bHLHd2; SREBP-2; SREBP2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC208942 representing NM_004599
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACGACAGCGGCGAGCTGGGTGGTCTGGAGACCATGGAGACCCTCACGGAGCTGGGCGACGAGCTGA CCCTGGGAGACATCGACGAGATGCTGCAATTTGTCAGTAATCAAGTGGGAGAGTTCCCTGACTTGTTTTC AGAACAGCTGTGTAGCTCCTTTCCTGGCAGTGGTGGTAGTGGTAGCAGCAGCGGCAGCAGTGGCAGCAGC AGCAGCAGCAGCAATGGCAGGGGCAGCAGCAGCGGAGCTGTGGACCCTTCAGTGCAACGGTCATTCACCC AGGTCACATTACCTTCCTTCTCTCCCTCGGCGGCCTCCCCACAGGCTCCAACTCTGCAAGTCAAGGTTTC TCCCACCTCAGTTCCCACCACACCCAGGGCAACTCCTATTCTTCAGCCCCGCCCCCAGCCCCAGCCTCAA CCTCAAACTCAGCTGCAACAACAGACGGTAATGATCACGCCAACATTCAGCACCACTCCGCAGACGAGGA TCATCCAGCAGCCTTTGATATACCAGAATGCAGCTACTAGCTTTCAAGTCCTTCAGCCTCAAGTCCAAAG CCTGGTGACATCCTCCCAGGTACAGCCGGTCACCATTCAGCAGCAGGTGCAGACAGTACAGGCCCAGCGG GTGCTGACACAAACGGCCAATGGCACGCTGCAGACCCTTGCCCCGGCTACGGTGCAGACAGTTGCTGCGC CACAGGTGCAGCAGGTCCCGGTCCTGGTCCAGCCTCAGATCATCAAGACAGATTCCCTTGTTTTGACCAC ACTGAAGACAGATGGCAGCCCTGTTATGGCTGCGGTCCAGAACCCGGCCCTCACCGCCCTCACCACCCCT ATCCAGACGGCTGCCCTTCAAGTACCAACCCTGGTGGGCAGCAGTGGGACCATTCTGACCACAATGCCTG TAATGATGGGGCAAGAGAAAGTGCCCATTAAGCAGGTACCTGGGGGAGTCAAGCAGCTTGAGCCCCCCAA AGAAGGAGAAAGGCGGACAACCCATAATATCATTGAGAAACGATATCGCTCCTCCATCAATGACAAAATC ATCGAATTGAAAGACCTGGTCATGGGGACAGACGCCAAGATGCACAAGTCTGGCGTTCTGAGGAAGGCCA TTGATTACATCAAATACTTGCAGCAGGTCAATCATAAACTGCGCCAGGAGAACATGGTGCTGAAGCTGGC AAATCAAAAGAACAAGCTTCTAAAGGGCATCGACCTAGGCAGTCTGGTGGACAATGAGGTGGACCTGAAG ATCGAGGACTTTAATCAGAATGTCCTTCTGATGTCCCCCCCAGCCTCTGACTCAGGGTCCCAGGCTGGCT TCTCTCCCTACTCCATTGACTCTGAGCCAGGAAGCCCTCTATTGGATGATGCAAAGGTCAAAGATGAGCC AGACTCTCCTCCTGTGGCGCTGGGCATGGTAGACCGCTCACGGATTCTTCTGTGTGTCCTCACCTTCCTG TGCCTCTCCTTTAACCCCCTGACTTCCCTGCTGCAGTGGGGAGGGGCCCACGACTCTGACCAGCACCCAC ACTCAGGCTCTGGCCGCAGTGTCCTGTCATTCGAGTCAGGTTCTGGGGGCTGGTTTGACTGGATGATGCC TACTCTTCTCTTATGGCTGGTAAATGGTGTGATTGTCCTGAGCGTCTTTGTGAAGCTTCTGGTTCATGGG GAGCCAGTGATCCGGCCACACTCGCGCTCCTCGGTCACCTTCTGGAGGCACCGGAAACAGGCAGATCTGG ATCTCGCCAGAGGAGATTTTGCAGCTGCTGCCGGCAACCTACAAACCTGCCTGGCAGTTTTGGGCCGGGC ACTGCCCACCTCCCGCCTGGACCTGGCCTGCAGCCTCTCCTGGAACGTGATCCGCTACAGCCTGCAGAAG CTACGCCTGGTGCGCTGGCTGCTCAAGAAAGTCTTCCAGTGCCGGCGGGCCACGCCAGCCACTGAGGCAG GCTTTGAAGACGAAGCTAAGACCAGCGCCCGGGATGCGGCTCTGGCCTATCACCGGCTGCACCAGCTGCA CATCACAGGGAAGCTTCCTGCAGGATCCGCCTGTTCCGATGTACACATGGCGTTGTGTGCCGTGAACCTG GCTGAATGTGCAGAGGAGAAGATCCCACCGAGCACACTGGTTGAGATCCATCTGACTGCTGCCATGGGGC TCAAGACCCGGTGTGGAGGCAAGCTGGGCTTCCTGGCCAGCTACTTCCTCAGCCGAGCCCAGAGCCTGTG TGGCCCCGAGCACAGTGCTGTTCCTGACTCCCTGCGCTGGCTCTGCCACCCCCTGGGCCAGAAGTTTTTC ATGGAGCGGAGCTGGTCTGTGAAGTCAGCTGCCAAGGAGAGTCTATACTGTGCCCAGAGGAACCCAGCTG ACCCCATTGCGCAGGTCCACCAGGCCTTCTGCAAGAACCTGCTGGAGCGAGCTATAGAGTCCTTGGTGAA ACCTCAGGCCAAGAAGAAGGCTGGAGACCAGGAAGAAGAGAGCTGTGAATTCTCCAGTGCTCTGGAGTAC TTGAAATTACTTCATTCTTTTGTGGACTCTGTGGGGGTTATGAGCCCCCCACTCTCCAGGAGCTCCGTGC TCAAGTCCGCCCTGGGTCCAGACATCATCTGTCGGTGGTGGACGTCTGCAATCACTGTGGCCATCAGCTG GCTCCAGGGAGACGATGCAGCTGTGCGCTCTCATTTTACCAAAGTGGAACGCATCCCCAAGGCCCTGGAA GTGACAGAGAGCCCCCTGGTGAAGGCCATCTTCCATGCCTGCAGAGCCATGCATGCCTCACTCCCTGGGA AAGCAGATGGGCAGCAGAGTTCCTTCTGCCATTGCGAGAGGGCCAGTGGCCACCTATGGAGCAGCCTCAA CGTCAGTGGGGCCACCTCTGACCCTGCCCTCAACCACGTGGTCCAGCTGCTCACCTGTGACCTGCTACTG TCGCTACGGACAGCGCTCTGGCAAAAACAGGCCAGTGCCAGCCAGGCTGTGGGGGAGACCTACCACGCGT CAGGCGCTGAACTGGCGGGCTTCCAACGGGACCTGGGCAGCCTGCGCAGGCTGGCACACAGCTTCCGCCC AGCATACCGCAAGGTGTTCCTGCATGAAGCCACCGTGCGCCTGATGGCAGGAGCCAGCCCCACCCGCACC CACCAGCTGCTGGAACACAGCCTGCGGCGGCGCACCACGCAGAGCACCAAGCACGGAGAGGTGGATGCCT GGCCCGGCCAGCGAGAGCGGGCCACCGCCATCCTGCTGGCCTGCCGCCACCTGCCCCTCTCCTTCCTCTC CTCCCCGGGCCAGCGGGCAGTGCTGCTGGCCGAAGCTGCCCGCACCCTGGAGAAGGTGGGCGACCGGCGC TCCTGCAACGACTGCCAGCAGATGATTGTTAAGCTGGGTGGTGGCACTGCCATTGCCGCCTCC AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA >RC208942 representing NM_004599
Red=Cloning site Green=Tags(s) MDDSGELGGLETMETLTELGDELTLGDIDEMLQFVSNQVGEFPDLFSEQLCSSFPGSGGSGSSSGSSGSS SSSSNGRGSSSGAVDPSVQRSFTQVTLPSFSPSAASPQAPTLQVKVSPTSVPTTPRATPILQPRPQPQPQ PQTQLQQQTVMITPTFSTTPQTRIIQQPLIYQNAATSFQVLQPQVQSLVTSSQVQPVTIQQQVQTVQAQR VLTQTANGTLQTLAPATVQTVAAPQVQQVPVLVQPQIIKTDSLVLTTLKTDGSPVMAAVQNPALTALTTP IQTAALQVPTLVGSSGTILTTMPVMMGQEKVPIKQVPGGVKQLEPPKEGERRTTHNIIEKRYRSSINDKI IELKDLVMGTDAKMHKSGVLRKAIDYIKYLQQVNHKLRQENMVLKLANQKNKLLKGIDLGSLVDNEVDLK IEDFNQNVLLMSPPASDSGSQAGFSPYSIDSEPGSPLLDDAKVKDEPDSPPVALGMVDRSRILLCVLTFL CLSFNPLTSLLQWGGAHDSDQHPHSGSGRSVLSFESGSGGWFDWMMPTLLLWLVNGVIVLSVFVKLLVHG EPVIRPHSRSSVTFWRHRKQADLDLARGDFAAAAGNLQTCLAVLGRALPTSRLDLACSLSWNVIRYSLQK LRLVRWLLKKVFQCRRATPATEAGFEDEAKTSARDAALAYHRLHQLHITGKLPAGSACSDVHMALCAVNL AECAEEKIPPSTLVEIHLTAAMGLKTRCGGKLGFLASYFLSRAQSLCGPEHSAVPDSLRWLCHPLGQKFF MERSWSVKSAAKESLYCAQRNPADPIAQVHQAFCKNLLERAIESLVKPQAKKKAGDQEEESCEFSSALEY LKLLHSFVDSVGVMSPPLSRSSVLKSALGPDIICRWWTSAITVAISWLQGDDAAVRSHFTKVERIPKALE VTESPLVKAIFHACRAMHASLPGKADGQQSSFCHCERASGHLWSSLNVSGATSDPALNHVVQLLTCDLLL SLRTALWQKQASASQAVGETYHASGAELAGFQRDLGSLRRLAHSFRPAYRKVFLHEATVRLMAGASPTRT HQLLEHSLRRRTTQSTKHGEVDAWPGQRERATAILLACRHLPLSFLSSPGQRAVLLAEAARTLEKVGDRR SCNDCQQMIVKLGGGTAIAAS SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_004599 |
| ORF Size | 3423 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004599.4 |
| RefSeq Size | 4325 bp |
| RefSeq ORF | 3426 bp |
| Locus ID | 6721 |
| UniProt ID | Q12772 |
| Domains | HLH |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 123.5 kDa |
| Gene Summary | This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation
,null,
Frontiers in Microbiology
,PubMed ID 35495674
[SREBP2]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208942L1 | Lenti ORF clone of Human sterol regulatory element binding transcription factor 2 (SREBF2), Myc-DDK-tagged |
CNY 14,320.00 |
|
| RC208942L2 | Lenti ORF clone of Human sterol regulatory element binding transcription factor 2 (SREBF2), mGFP tagged |
CNY 13,300.00 |
|
| RC208942L3 | Lenti ORF clone of Human sterol regulatory element binding transcription factor 2 (SREBF2), Myc-DDK-tagged |
CNY 13,300.00 |
|
| RC208942L4 | Lenti ORF clone of Human sterol regulatory element binding transcription factor 2 (SREBF2), mGFP tagged |
CNY 14,320.00 |
|
| RG208942 | SREBF2 (tGFP-tagged) - Human sterol regulatory element binding transcription factor 2 (SREBF2) |
CNY 13,520.00 |
|
| SC127910 | SREBF2 (untagged)-Human sterol regulatory element binding transcription factor 2 (SREBF2) |
CNY 11,928.00 |
