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TEA domain family member 2 (TEAD2) (NM_003598) Human Tagged ORF Clone
CAT＃: RC203526
- TrueORF®
TEAD2 (Myc-DDK-tagged)-Human TEA domain family member 2 (TEAD2)
ORF Plasmid: tGFP
"NM_003598" in other vectors (6)
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CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | ETF; TEAD-2; TEF-4; TEF4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC203526 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGGAACCCCGGGCTGGGGCCGCCCTGGACGATGGCAGCGGCTGGACGGGCAGTGAGGAAGGCAGTG AGGAGGGTACCGGCGGCAGTGAGGGGGCTGGGGGTGACGGGGGCCCGGATGCAGAGGGGGTGTGGAGCCC AGACATTGAGCAGAGCTTCCAGGAGGCCCTGGCCATCTATCCACCCTGCGGCCGCCGGAAAATAATTTTG TCTGATGAAGGCAAGATGTATGGTCGGAATGAACTGATCGCCCGCTACATCAAGCTGAGAACGGGGAAGA CCCGAACTCGAAAACAGGTTTCTAGTCACATCCAGGTTTTGGCCCGAAGGAAATCAAGGGAAATCCAGTC CAAGTTGAAGGACCAGGTTTCCAAGGACAAGGCTTTCCAGACAATGGCAACCATGTCCTCTGCCCAGCTC ATCTCCGCGCCTTCTCTGCAGGCCAAACTGGGTCCCACTGGTCCTCAGGCCTCTGAGCTTTTCCAGTTTT GGTCTGGAGGATCTGGGCCCCCCTGGAATGTTCCAGATGTGAAGCCATTCTCACAGACACCGTTCACCTT GTCACTGACTCCCCCATCTACTGACCTCCCAGGGTACGAGCCCCCCCAAGCCCTCTCACCCCTGCCCCCA CCTACCCCATCGCCCCCAGCCTGGCAGGCTCGGGGCCTGGGCACCGCCCGGTTGCAGCTGGTAGAGTTCT CAGCCTTCGTGGAACCGCCAGATGCAGTTGATTCTTACCAGAGGCACCTGTTCGTGCACATCAGCCAGCA CTGCCCCAGCCCCGGAGCGCCGCCGCTCGAGAGTGTGGACGTCCGGCAGATCTACGACAAATTCCCTGAG AAAAAGGGTGGCCTCCGAGAGCTATATGATCGTGGCCCCCCCCATGCCTTCTTCCTGGTCAAGTTCTGGG CGGACCTGAACTGGGGCCCAAGTGGTGAGGAGGCAGGGGCCGGTGGCAGCATCAGCAGTGGTGGCTTCTA CGGAGTGAGCAGCCAGTATGAGAGCCTGGAACACATGACCCTCACCTGTTCCTCCAAGGTCTGCTCTTTT GGCAAGCAGGTGGTGGAGAAGGTGGAGACGGAACGGGCCCAGCTGGAGGACGGCAGATTTGTGTACCGCC TGCTGCGCTCGCCCATGTGCGAGTACCTGGTGAATTTCTTGCACAAGTTGCGGCAGCTGCCTGAGCGATA CATGATGAACAGCGTCCTGGAAAACTTCACCATCCTCCAGGTGGTGACAAACAGAGACACCCAGGAACTG CTGCTCTGCACCGCCTATGTCTTCGAGGTCTCCACCAGCGAGCGTGGGGCCCAGCATCACATTTACCGCC TGGTCAGGGAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC203526 protein sequence
Red=Cloning site Green=Tags(s) MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLKDQVSKDKAFQTMATMSSAQL ISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPFSQTPFTLSLTPPSTDLPGYEPPQALSPLPP PTPSPPAWQARGLGTARLQLVEFSAFVEPPDAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPE KKGGLRELYDRGPPHAFFLVKFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSF GKQVVEKVETERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL LLCTAYVFEVSTSERGAQHHIYRLVRD TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_003598 |
| ORF Size | 1341 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003598.2 |
| RefSeq Size | 2220 bp |
| RefSeq ORF | 1344 bp |
| Locus ID | 8463 |
| UniProt ID | Q15562 |
| Protein Families | Transcription Factors |
| MW | 49.2 kDa |
| Gene Summary | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Human Papillomavirus 16 E6 Up-regulates APOBEC3B via the TEAD Transcription Factor
,Mori, S;Takeuchi, T;Ishii, Y;Yugawa, T;Kiyono, T;Nishina, H;Kukimoto, I;,
J. Virol
,PubMed ID 28077648
[TEA domain family member 2]
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Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203526L1 | Lenti ORF clone of Human TEA domain family member 2 (TEAD2), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203526L2 | Lenti ORF clone of Human TEA domain family member 2 (TEAD2), mGFP tagged |
CNY 5,890.00 |
|
| RC203526L3 | Lenti ORF clone of Human TEA domain family member 2 (TEAD2), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203526L4 | Lenti ORF clone of Human TEA domain family member 2 (TEAD2), mGFP tagged |
CNY 7,888.00 |
|
| RG203526 | TEAD2 (tGFP-tagged) - Human TEA domain family member 2 (TEAD2) |
CNY 7,088.00 |
|
| SC320274 | TEAD2 (untagged)-Human TEA domain family member 2 (TEAD2) |
CNY 5,488.00 |
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