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RAB11A (NM_004663) Human Tagged ORF Clone
CAT＃: RC200352
RAB11A (Myc-DDK-tagged)-Human RAB11A, member RAS oncogene family (RAB11A), transcript variant 1
ORF Plasmid: tGFP
"NM_004663" in other vectors (6)
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CNY 3,600.00
CNY 3,705.00
| Cited in 4 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | YL8 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC200352 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGCACCCGCGACGACGAGTACGACTACCTCTTTAAAGTTGTCCTTATTGGAGATTCTGGTGTTGGAA AGAGTAATCTCCTGTCTCGATTTACTCGAAATGAGTTTAATCTGGAAAGCAAGAGCACCATTGGAGTAGA GTTTGCAACAAGAAGCATCCAGGTTGATGGAAAAACAATAAAGGCACAGATATGGGACACAGCAGGGCAA GAGCGATATCGAGCTATAACATCAGCATATTATCGTGGAGCTGTAGGTGCCTTATTGGTTTATGACATTG CTAAACATCTCACATATGAAAATGTAGAGCGATGGCTGAAAGAACTGAGAGATCATGCTGATAGTAACAT TGTTATCATGCTTGTGGGCAATAAGAGTGATCTACGTCATCTCAGGGCAGTTCCTACAGATGAAGCAAGA GCTTTTGCAGAAAAGAATGGTTTGTCATTCATTGAAACTTCGGCCCTAGACTCTACAAATGTAGAAGCTG CTTTTCAGACAATTTTAACAGAGATTTACCGCATTGTTTCTCAGAAGCAAATGTCAGACAGACGCGAAAA TGACATGTCTCCAAGCAACAATGTGGTTCCTATTCATGTTCCACCAACCACTGAAAACAAGCCAAAGGTG CAGTGCTGTCAGAACATC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC200352 protein sequence
Red=Cloning site Green=Tags(s) MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEAR AFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKV QCCQNI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_004663 |
| ORF Size | 648 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004663.5 |
| RefSeq Size | 4943 bp |
| RefSeq ORF | 651 bp |
| Locus ID | 8766 |
| UniProt ID | P62491 |
| Domains | ras, RAN, RAS, RHO, RAB |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis |
| MW | 24.4 kDa |
| Gene Summary | The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Rab11 Functions as an Oncoprotein via Nuclear Factor kappa B (NF-κB) Signaling Pathway in Human Bladder Carcinoma
,Gong, X;Liu, J;Zhang, X;Dong, F;Liu, Y;Wang, P;,
Med. Sci. Monit.
,PubMed ID 30032159
[RAB11A]
|
|
Rab11a promotes proliferation and invasion through regulation of YAP in non-small cell lung cancer
,Dong, Q;Fu, L;Zhao, Y;Du, Y;Li, Q;Qiu, X;Wang, E;,
Oncotarget
,PubMed ID 28468127
[RAB11A]
|
|
Rab11a sustains GSK3ß/Wnt/ß-catenin signaling to enhance cancer progression in pancreatic cancer
,Yu, L;Li, X;Li, H;Chen, H;Liu, H;,
Tumour Biol.
,PubMed ID 27481517
[Rab11a]
|
|
RAB11A Is Essential for Transport of the Influenza Virus Genome to the Plasma Membrane
,Amie J. Eisfeld, Eiryo Kawakami, Tokiko Watanabe, Gabriele Neumann, and Yoshihiro Kawaoka,
J. Virol., Jul 2011; 85: 6117 - 6126.
[RAB11A]
|
Documents
| Product Manuals |
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200352L1 | Lenti ORF clone of Human RAB11A, member RAS oncogene family (RAB11A), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC200352L2 | Lenti ORF clone of Human RAB11A, member RAS oncogene family (RAB11A), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC200352L3 | Lenti ORF clone of Human RAB11A, member RAS oncogene family (RAB11A), transcript variant 1, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC200352L4 | Lenti ORF clone of Human RAB11A, member RAS oncogene family (RAB11A), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG200352 | RAB11A (tGFP-tagged) - Human RAB11A, member RAS oncogene family (RAB11A), transcript variant 1 |
CNY 5,200.00 |
|
| SC127144 | RAB11A (untagged)-Human RAB11A, member RAS oncogene family (RAB11A), transcript variant 1 |
CNY 3,600.00 |
