Sh2b2 (NM_001302938) Mouse Tagged ORF Clone
CAT#: MR230712
- TrueORF®
Sh2b2 (myc-DDK-tagged) - Mouse SH2B adaptor protein 2 (Sh2b2), transcript variant 2
"NM_001302938" in other vectors (1)
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CNY 4,624.00
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | Aps |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR230712 representing NM_001302938
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAATGGTGCCACCCCCAGCTCGGCCGCCGCCCCCGCCCCAGTCCCCGACTGGCGGCAATTCTGCGAGC TGCACGCGCAGGTGGCTGCTGTGGACTTCGCACACAAGTTCTGCCGCTTCCTTCGGGACAACCCGACCTA CGACACGCCTGACGCTGGGACCTCATTCTCCCGCCACTTTGCAGCCAACTTCTTGGCTGTCTTCAGTGAG GAGGTGCGCCGCGTGCTGGGGTCAGCAGCCGACACTATGGAACCCGAGCCTGCGGTGACCTCGGTGACAT CTGCGCTCAAGACTGCAACCTATGGCCACTCCCGCAGCTCCGAGGATGTGTCTGCCCACGCGGCTACCAA GGCGCGTGTCCGAAAGGGATTCTCGCTGCGTAACATGAGCCTGTGTGTGGTGGATGGAGTGCGCGACCTG TGGCACCGGCGCTCGTCCCCAGAGCCCGATGGTGGGGCCACCCCCAAGGCCGCCGAGCCTGCGTCGGAGC CTCGTGACAAATGGACGCGACGCCTGCGGCTAGCACGAACCCTGGCAGCCAAAGTGGAGTTAGTGGACAT CCAGCGTGAGGGCGCCCTGCGCTTCATGGTGGCAGACGACGCGGCCTCAGGGCCTGGAGGCACTGCGCAG TGGCAGAAGTGTCGCCTGCTCCTGCGGAGGGCTGTGGCTGGGGAACGTTTCCGCCTGGAGTTCTTCGTGC CACCCAAGGCTTCCAGACCCAAGGTCAGCATCCCCCTGTCGGCCATCATTGAGGTCCGAACCACTATGCC CCTGGAAATGCCTGAAAAGGACAACACATTTGTGCTCAAGGTGGAGAACGGAGCAGAATACATCCTGGAA ACGATAGACTCACTGCAGAAGCACTCGTGGGTGGCTGACATCCAGGGCTGTGTGGATCCTGGGGACAGTG AGGAAGACACAGGACTGTCTTGTGCACGGGGAGGCTGCCTGGCCAGCCGCGTGGCCTCCTGCAGCTGTGA GCTCCTGACAGATGCAGACATGCCCCGGCCCCCCGAGACGACGACAGCGGTGGGTGCTGTGGTCACAGCT CCACATGGCCGAGCTCGTGACACCGTGGGAGAGTCCCTGGCCCACGTTCCCCTGGAGACTTTCCTGCAAA CCCTGGAGTCTTCAGGTGGTGTCAGTGAGAACAATAACCCAGGGGACGAAGGAGCTGAGCTGGACACCGA TGCTGAGGCTGAGCTGGAACTTTCCGACTACCCCTGGTTCCATGGGACATTGTCCCGGGTGAAGGCGGCC CAGCTTGTGCTGGCCGGTGGCCCTCGGAGCCATGGCCTCTTTGTGATCCGCCAAAGTGAGACTAGGCCTG GGGAGTGTGTGCTGACCTTCAACTTCCAGGGCAAGGCCAAGCACCTCCGCCTTTCTCTGAACGGTCACGG CCAGTGTCATGTCCAGCACCTGTGGTTCCAGTCCGTGTTTGATATGCTCCGTCACTTCCACACCCACCCC ATCCCCCTGGAGTCAGGAGGATCGGCTGATATCACCCTAAGAAGCTATGTGCGTGCCCAGGGCCCGCCTC CTGATCCAGGACCAGCGCCCAACACTGCGGCCCCAGTTCCAGCCTGCTGGACGGAGCCGGCTGGCCAGCA CTACTTCTCCAGCCTGGCCACGGCCACTTGCCCGCCCGCTTCACCGTCCAATGGCGCTGGAGCTTCGTCT TCATCCGGCTCATCGTCCTCTGCCACATCCCTGCCCCCACGCCCAGCCGAGGGGCCGCTCAGTGCGCACA GCCGCAGCAACAGCACAGAGCACCTGCTGGATGCTGCATCTGGAGCCACTGAGGAGCCCACAGAGGCCAC GCTGGGCCGTGCTCGTGCTGTGGAGAATCAGTACTCCTTTTAC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR230712 representing NM_001302938
Red=Cloning site Green=Tags(s) MNGATPSSAAAPAPVPDWRQFCELHAQVAAVDFAHKFCRFLRDNPTYDTPDAGTSFSRHFAANFLAVFSE EVRRVLGSAADTMEPEPAVTSVTSALKTATYGHSRSSEDVSAHAATKARVRKGFSLRNMSLCVVDGVRDL WHRRSSPEPDGGATPKAAEPASEPRDKWTRRLRLARTLAAKVELVDIQREGALRFMVADDAASGPGGTAQ WQKCRLLLRRAVAGERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILE TIDSLQKHSWVADIQGCVDPGDSEEDTGLSCARGGCLASRVASCSCELLTDADMPRPPETTTAVGAVVTA PHGRARDTVGESLAHVPLETFLQTLESSGGVSENNNPGDEGAELDTDAEAELELSDYPWFHGTLSRVKAA QLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVFDMLRHFHTHP IPLESGGSADITLRSYVRAQGPPPDPGPAPNTAAPVPACWTEPAGQHYFSSLATATCPPASPSNGAGASS SSGSSSSATSLPPRPAEGPLSAHSRSNSTEHLLDAASGATEEPTEATLGRARAVENQYSFY TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001302938 |
ORF Size | 1863 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001302938.1, NP_001289867.1 |
RefSeq Size | 2900 bp |
RefSeq ORF | 1866 bp |
Locus ID | 23921 |
UniProt ID | Q9JID9 |
MW | 66.6 kDa |
Gene Summary | Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3 (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC228501 | Sh2b2 (untagged) - Mouse SH2B adaptor protein 2 (Sh2b2), transcript variant 2 |
CNY 6,080.00 |