Hps6 (NM_176785) Mouse Tagged ORF Clone
CAT#: MR221499
- TrueORF®
Hps6 (Myc-DDK-tagged) - Mouse Hermansky-Pudlak syndrome 6 (Hps6)
ORF Plasmid: tGFP
"NM_176785" in other vectors (4)
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CNY 5,896.00
CNY 7,130.00
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | 5330434M19Rik; BLOC2; ru |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR221499 representing NM_176785
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGCGTGCAGGAACTCTGCGCCTGCTTTCGGATCTGAGCAACTTCACCGGCGCGGCCCGGCTCCGCG AGTTGTTGGCGGGGGACCCAGCTGTCCTAGTCCGCTGCAGCCCTGACGGCCGCCACTTGCTGCTATTAAG ACCCCCCGGATCGCCCGCCCCACAGCTTCTAGTGGCTGTGCGTGGGCCCGGCCTGCCGCTGGAGCGTGCC TGGCCGGAGGGCGACCCCTCGCCGCTGGACGTCTTTTTCGTGCCGTGGCTGGCGCGACCCGCGCTGATCT TGGTATGGGAGAGTGGCCTAGCAGAGGTTTGGGGCGTGGGGATGGAGCCTGGATGGAAGCTACTTCAGAG CACTGAGCTGTGTCCGGATGGTGGAGCCCGCGTGATGGCCGTGGCCGCAACCCGAGGCCGCCTAGTTTGG TGCGAGGAGCGTCAGCCGGGTGTTAAGGACCAACCAGAGCAGCTTTCAACGGCCTTCAGCCACCGTGTGT GCTTCAAGACCCTGGAAACCAGCGGGGAGGCTGGCACCAAACTAGGCTGCACCCACATCCTGCTACACCA TTGCCCCCTTTTTGGACTGATAGCCTCCCGCAAGGACCTCTTCCTGGTGCCTACTACCAACACTTGGTCT GGTGTGGCCCACCTTCTGCTCATCTGGAGCCCAAGCAAGGGGAAGGTAATAGTTGCTGCTCCATCTCTTG GTCTTTCACACAGTAAAAGCCTGAATCCCAAACAAGGGGACACTTGGGACTTCCGGACCCTGCTGCGAGG CCTTCCTGGATTCCTGTCCCCCAGGGAGCCACTGGCTGTACACACTTGGGCCCCATCTTCGCAGGGCTTG TTGTTGCTTGACTTGAAAGGGAAGGTGAGCCTAGTGCAGTGCCATGGTGGTACTCGAACCGTGGGAATCC TGCAGGAGGCCCCTGTAAGCCTAAAAGGGTCTGCAGCCCTGGGGACATTTCACGGCACTTTAGCCTGTGT CCTGGGCTCCACCTTGGAACTACTGGACATGAGCAGTGGGCGGCTGTTGGAAAAAAAGGTTCTCAGTACA GACAGAGTACATTTGCTGGAGCCTCCAGCCCCGGGCATGAAGAACGAGGAAGAGCTGGAGACCCGAGGAG CCCTACGATTGCTTTCAGCCTTGGGTCTCTTTTGTGTGTGTTGGGAAACTCCCCAAGGCCTTGAGCTGCC TTCAGACAAGGACCTGGTGTTTGAGGAGGCCTGTGGGTACTACCAGCGTCGGAGCCTTCGAGGTACCCAG CTTACCCCAGAAGAACTGAGACACAACAGCATGTTTCGGGCACCTCAGGCCCTGGCCTCCATCCTCCAGG GCCACCTGCCCCCGTCTACACTCCTGACAACCCTGAGGGCTGAGCTCCGGGATTATCGTAGTATAGAACA GCTCAAGGCCCAGCTGGTGGCTGGGGACGATGAGGAGGCTGGCTGGACTGAGTTAGCGGAGCACGAGGTG GCCCGCCTGCTGAGAACCCAGTTGACAGGAGACCAGCTGGCCCAATTCAACACCATTTTCCAAGCCCTTC CTACAGCAGCTTGGGGTGCCACCCTCCAGGCACTGCAGCTCCAGCCAGATAGGAGTGGCAGGCTGAGGTC CCAAGCACCCCCGGATGTATGGAAGAAGGTCCTAAGGGCTCCAACAGCTGGAAAGGAACATCCCAATGGA ATACTGCCGCCCTTTGAACTCCTGTGTCAGTGCCTGGGCCAGCTCGAGCCTCAGTGGCTCCCCCCATTTG TGAAACTGGCACAGCAGCAGGGTGGCCCCGGCTGGGGGGCTGAAGGCCCCAGTCTGCCCCTTTACCGCCG AGCCCTGGCAGTGCTAGGTGAGGAAGGGAAGAGGCCTGAGGCTCTGGAACTCGAGTTGCTTTTGGGCAGT GGGCGACCCAAAGCCGTGCTACAAGCTGTAAGGCAGCTGATAAAGAAAGAAGAGTGGGAACGGGCTCTGG AAGCCGGGCTGGCCCTGGATGCCTCCAGCCCCCTGCTTCGAAGTGAGATCTTTAAGCTGCTGCTGGCAGA GTTTGCCCAGCACCGCCGCCTGGATGCACACCTCCCTCTCCTCTGTCGCCTGTGCCCACCGGAAGTGGCT CCACATGAGCTCCTACTTCTGCTGAGGACACATCTCCCAGATGATGAGGGAACCACCCCTTTCCCTGAGC CTGGGGCAGAGCCCCCTCTCACAGTGGGCTTGGTCAGAGCCCTGCTAGAACAGACTGGGGCTCAAGGAAG GCCGTCTGGCCCAGTTCAAAGCACCTATGAGGACATCTTATGGGACCCAGGCACTCCACCCCCTACACCA CCTCGTGGACCCACTGCTTCTCTCCCGGCATCAGACCATCCAGGACAAGAAGCCTGGGTACCACCTGGAC AAGGGCTCGGTGCAGCTGATGTGGGAGTTCATTTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR221499 representing NM_176785
Red=Cloning site Green=Tags(s) MKRAGTLRLLSDLSNFTGAARLRELLAGDPAVLVRCSPDGRHLLLLRPPGSPAPQLLVAVRGPGLPLERA WPEGDPSPLDVFFVPWLARPALILVWESGLAEVWGVGMEPGWKLLQSTELCPDGGARVMAVAATRGRLVW CEERQPGVKDQPEQLSTAFSHRVCFKTLETSGEAGTKLGCTHILLHHCPLFGLIASRKDLFLVPTTNTWS GVAHLLLIWSPSKGKVIVAAPSLGLSHSKSLNPKQGDTWDFRTLLRGLPGFLSPREPLAVHTWAPSSQGL LLLDLKGKVSLVQCHGGTRTVGILQEAPVSLKGSAALGTFHGTLACVLGSTLELLDMSSGRLLEKKVLST DRVHLLEPPAPGMKNEEELETRGALRLLSALGLFCVCWETPQGLELPSDKDLVFEEACGYYQRRSLRGTQ LTPEELRHNSMFRAPQALASILQGHLPPSTLLTTLRAELRDYRSIEQLKAQLVAGDDEEAGWTELAEHEV ARLLRTQLTGDQLAQFNTIFQALPTAAWGATLQALQLQPDRSGRLRSQAPPDVWKKVLRAPTAGKEHPNG ILPPFELLCQCLGQLEPQWLPPFVKLAQQQGGPGWGAEGPSLPLYRRALAVLGEEGKRPEALELELLLGS GRPKAVLQAVRQLIKKEEWERALEAGLALDASSPLLRSEIFKLLLAEFAQHRRLDAHLPLLCRLCPPEVA PHELLLLLRTHLPDDEGTTPFPEPGAEPPLTVGLVRALLEQTGAQGRPSGPVQSTYEDILWDPGTPPPTP PRGPTASLPASDHPGQEAWVPPGQGLGAADVGVHL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
![]() Sequencher program is needed, download here. |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_176785 |
ORF Size | 2415 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_176785.3, NP_789742.2 |
RefSeq Size | 2696 bp |
RefSeq ORF | 2418 bp |
Locus ID | 20170 |
UniProt ID | Q8BLY7 |
MW | 87.3 kDa |
Gene Summary | May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules (By similarity). Acts as cargo adapter for the dynein-dynactin motor complex to mediate the transport of lysosomes from the cell periphery to the perinuclear region. Facilitates retrograde lysosomal trafficking by linking the motor complex to lysosomes, and perinuclear positioning of lysosomes is crucial for the delivery of endocytic cargos to lysosomes, for lysosome maturation and functioning (PubMed:25189619).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC221755 | Hps6 (untagged) - Mouse Hermansky-Pudlak syndrome 6 (Hps6), (10ug) |
CNY 10,360.00 |
|
MG221499 | Hps6 (tGFP-tagged) - Mouse Hermansky-Pudlak syndrome 6 (Hps6), (10ug) |
CNY 7,890.00 |
|
MR221499L3 | Lenti ORF clone of Hps6 (Myc-DDK-tagged) - Mouse Hermansky-Pudlak syndrome 6 (Hps6) |
CNY 9,030.00 |
|
MR221499L4 | Lenti ORF clone of Hps6 (mGFP-tagged) - Mouse Hermansky-Pudlak syndrome 6 (Hps6) |
CNY 9,030.00 |