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Senp6 (NM_146003) Mouse Tagged ORF Clone
CAT＃: MR210918
- TrueORF®
Senp6 (Myc-DDK-tagged) - Mouse SUMO/sentrin specific peptidase 6 (Senp6)
"NM_146003" in other vectors (3)
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CNY 7,880.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 2810017C20Rik; E130319N12Rik; mKIAA0797; Susp1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR210918 representing NM_146003
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGCGGGCAAGAGCGGTGGCAGCGCTGGGGCTCTTTTCCTGAAAGCTTTGGATAGATCAGAATCTA AGAGGGATGGAGGCTTTAAAAATAATTGGAGCTTTGATCATGAAGAAGAAAGTGAAGGAGATGCAGACAA AGATGGGGCAAATCTACTCAGTGTAGAAGATGAGGATTCTGAAATCTCAAAAGGAAAAAAGTTAAATCGG AGATCTGAAATTGTTGCTACTAGTTCTGGTGATTTCATCTTGAAGACTTATGTAAGGCGGAGCAAGACTG ACGGCTTTAAAACTTTGAAAGGCAACCCAATTGGACTTAACATGTTAAGCAACAATAAGAAACTGAGTGA AAGCACCGCAGGCACAGCATTATGTTCTGGAACTGTGGTTCATGGGAGGCGCTTCCATCATGCTCACTCA CAGACGCCAGGCATCAGAACAGCGGCTCAGAGGAAAGAATACCCACCTTATGTCCACAAAGCTGAAAACA GCCCTGTAATGCTAAGTCATGGCCAAGGTGGAGACCATATAATGAAGAAAACTGAAGAGTCAGAATCATA TGTAGAGTCTGAGATTAAGAGGAAAGTCCAGCAGAAGCGGCACTGTAGCACTTACCAGCTTTCTCCTCTG TCCCCTGCCTCAAAGAAGTGTTTGACCCATTTAGAGGTTTCTGAACAGCGTGAATATTGCCCAAAATGTG GAAAAGAAAAAGAAAATCAGACCAAATGCCAAAGTTGTGGTATTGTTTTTCATAATGATTTGCAAAGAAA TTGCCGACAAGCCGTAACTTTGAATGAACCTACTGGACCATTGCTAAGAACATCAATTCATCAGAACTCT GGAGGACAGAAATCACAAAACACAGGACTAACAGCTAAGAAATTTTATGGGAACAGTGTGGATAAGATTC CAATTGATATTTTGGTCACCTGTGATGATAGCAGACATAATTACATACAGACAAATGGGAAAGTCATTTT ACCTGGAGGAAAAATACCTAAACTCACAAACCCAAAAGAGCGAAAGATAAGCGTGTCAGATTTAAACGAT CCAATCATTTTGTCTAGTGATGATGATGACGACGACGACGATAGGACTAAGAGAAGAGAGAGCACGTCCC CGAAGCCTGCCGACTCAGCATGCTCCTCACCAGTACCATCTACGGGAAAAGTTGAAGCTGCACTAAATGC AGATGCCTGTAGAGCAGAGCAGGAACCCAGAAGCAGTCCAGCAGAGCCTGAGTTAAATACCATTGTCATA CCACGAAAAGCAAGAATGAAGGACCAGCTTGGTAATTCCATCAGCACACCTTTAAAACGTCGTAAAGTAA ACAGTCATGCAGCTTTTATTCACCCTATGTCTTTAAGTTGCCAAAACTTTGAAAGTGTCATTTTAAACTG CCGAAGTATACGAGTTGGAACACTCTTCCGACTGTTGGTAGAGCCTGTAATTTTTTCTTTAGAGTCAATC ACGATACATCTAGATGGACCAGAAAGTGATCCTGTAGACATTATTTTAAATACCTCTGATCTAACTAAAT GTGAATGGTGTAATGTCCGGAAATTACCAGTAGTGTTTCTCCAGGCAATACCAGCAGTTTACCAGAAGCT GAGCATGCAGCTACAGATGAGTAAAGAAGATAAAGTTTGGAATGATTGTAAAGGAATAAACAGGATAACA AGTTTAGAAGAACAGTACATTATTTTAATTTTTCAAACTGGCCTTGATCATCAGGCAGAGGTGGTCTTTG AAAGTATCATTACTGACATTGGTATAAGGAATAATGTTCCCAACTTTTTTGCAAAAATTCTTTTTGACGA AGCCAATAGCAGACTTGTTGCCTGTACAAGAAGCTATGAAGAGAGCATCAAAGGAAACTGCGCGCAAAAA GAGAACAAAGTGAAAACTGTGTCGTTTGAATCTAAAATACAACTTAGAAGCAAACAAGAATTGCAGTTTT TTGATGATGACGAAGAAGCTGGGGAGAGCCATACAATCTTCATTGGCCCTGTAGAAAAATTGATAGTATA CCCACCACCTCCAGCTAAGGGAGGCATTTCTGTTACTAATGAGGACCTGCACTGTCTAAGTGAAGGAGAG TTTTTAAATGATGTTATTATCGACTTTTATTTGAAATACTTGGTGCTTGAAAAACTGAAGAAAGAAGACG CTGACCGAATTCATATATTTAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGAGAAATCCTGA GACAACTAATCTGTCGATACAACAAAAACGGCATGGGAGAGTAAAAACGTGGACACGGCATGTAGATATT TTTGAGAAGGACTTTATTTTTGTACCCCTTAATGAAGCTGCACATTGGTTTTTGGCTGTTGTTTGTTTCC CTGGTTTGGAAAAACCAAAATATGAACCTAATCCTCATTACCATGAAAATGCAGTCATGCAAAAAACTCC AAGTGCAGAGGACAGTTGTGTTTCTTCTGCCAGTGAGATGGGTGCTTGTTCACAGAACTCTGCTGCCAAG CCTGTGATCAAGAAGATGTTAAATAGAAAACATTGCTTAGCTGTGACTGATTCGAGTGCTGCACAGGAAG AAAGTGAGCCTTGTTACCGGAGAAACGCATACAGTGTAAAGTGTAGTATGAAAAAAAAAAATCATGCTAT CAATGAAAATGAAGAACCAAGTAACGGAGAATCTACGTGCCAGGACATTTGTGATAGAACCCAAAGTGAG AATGGCCTCCGGGATGAATGCTTCAGTTCTGTACATCATCCAGATGCCTTAAGCAAAATCAGACTAAACT ACGGTGATCAGTCAGCAGACGGTGGGAAGCTGCTTGAAGATGAGCTCATTGACTTCTCAGAGGATCAGGA TGACCCGGATGATAGCAGTGATGACGGACTCCTTGCTGATGAAAACTACAGTTCAGAAATAGGACAGTGG CATTTAAAGCCTACTGTCTGTAAACAACCTTGTATCCTCCTTATGGACTCACTCAGAGGCCCTTCTCGTT CAAATGTTGTCAAAATTCTAAGAGAGTATTTAGAAGTGGAATGGGAGGTGAAAAAAGGAAGCAAAAGAAG TTTTTCCAAAGATGTTATGAAAGGGTCCAACCCAAAAGTCCCACAACAGAACAACTTCAGTGACTGTGGT GTCTATGTGCTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAGTACTAAATTTTGAGCTCCCTATGAATT TGATGAACTGGTTTCCTCCCCCCAGAATGAAAACAAAAAGAGAAGAAATCCGAAACATAATTTTGAAGCT ACAGGAATCACAGAGTAAAGACAAGAAGCTGCTGAAGGACTCCTTAGCAGAGACGTCCTTAGGGGACGGA GCAGAGCAGTACGCCAGCGCCAGCGGTGGCTCAGAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR210918 representing NM_146003
Red=Cloning site Green=Tags(s) MAAGKSGGSAGALFLKALDRSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSEISKGKKLNR RSEIVATSSGDFILKTYVRRSKTDGFKTLKGNPIGLNMLSNNKKLSESTAGTALCSGTVVHGRRFHHAHS QTPGIRTAAQRKEYPPYVHKAENSPVMLSHGQGGDHIMKKTEESESYVESEIKRKVQQKRHCSTYQLSPL SPASKKCLTHLEVSEQREYCPKCGKEKENQTKCQSCGIVFHNDLQRNCRQAVTLNEPTGPLLRTSIHQNS GGQKSQNTGLTAKKFYGNSVDKIPIDILVTCDDSRHNYIQTNGKVILPGGKIPKLTNPKERKISVSDLND PIILSSDDDDDDDDRTKRRESTSPKPADSACSSPVPSTGKVEAALNADACRAEQEPRSSPAEPELNTIVI PRKARMKDQLGNSISTPLKRRKVNSHAAFIHPMSLSCQNFESVILNCRSIRVGTLFRLLVEPVIFSLESI TIHLDGPESDPVDIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSMQLQMSKEDKVWNDCKGINRIT SLEEQYIILIFQTGLDHQAEVVFESIITDIGIRNNVPNFFAKILFDEANSRLVACTRSYEESIKGNCAQK ENKVKTVSFESKIQLRSKQELQFFDDDEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGE FLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNPETTNLSIQQKRHGRVKTWTRHVDI FEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKTPSAEDSCVSSASEMGACSQNSAAK PVIKKMLNRKHCLAVTDSSAAQEESEPCYRRNAYSVKCSMKKKNHAINENEEPSNGESTCQDICDRTQSE NGLRDECFSSVHHPDALSKIRLNYGDQSADGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYSSEIGQW HLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCG VYVLQYVESFFENPVLNFELPMNLMNWFPPPRMKTKREEIRNIILKLQESQSKDKKLLKDSLAETSLGDG AEQYASASGGSE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_146003 |
| ORF Size | 3396 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_146003.2, NP_666115.2 |
| RefSeq Size | 4938 bp |
| RefSeq ORF | 3399 bp |
| Locus ID | 215351 |
| UniProt ID | Q6P7W0 |
| MW | 127.5 kDa |
| Gene Summary | Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly-SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation. Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC223670 | Senp6 (untagged) - Mouse SUMO/sentrin specific peptidase 6 (Senp6), (10ug) |
CNY 14,540.00 |
|
| MR210918L3 | Lenti ORF clone of Senp6 (Myc-DDK-tagged) - Mouse SUMO/sentrin specific peptidase 6 (Senp6) |
CNY 11,780.00 |
|
| MR210918L4 | Lenti ORF clone of Senp6 (mGFP-tagged) - Mouse SUMO/sentrin specific peptidase 6 (Senp6) |
CNY 11,780.00 |
