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Bicd2 (NM_001039180) Mouse Tagged ORF Clone
CAT＃: MR210810
- TrueORF®
Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 3
"NM_001039180" in other vectors (2)
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CNY 5,464.00
CNY 6,560.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 0610027D24Rik; 1110005D12Rik; AA408834; mKIAA0699 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR210810 representing NM_001039180
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCAGCTCAAAGAGGCATTTGGCCAGGCACATACAAACCACAAGAAGGTGGCTGCTGATGGTGAGA GCCGGGAGGAGAGCCTGATCCAGGAGTCGGCCTCCAAGGAGCAGTACTACGTGCGGAAGGTGCTGGAGCT GCAGACAGAGCTGAAACAGCTGCGCAACGTCCTCACCAACACCCAGTCTGAGAATGAGCGCCTCACGTCT GTGGCCCAGGAGCTAAAAGAGATCAACCAGAATGTGGAGATCCAGCGTGGTCGCCTGCGGGATGACATCA AGGAGTACAAGTTCCGGGAGGCCCGTCTACTTCAGGACTACTCAGAGCTGGAGGAGGAGAACATCAGCCT GCAGAAACAAGTGTCTGTGCTCAGGCAGAACCAGGTGGAGTTTGAGGGCCTCAAGCATGAAATCAAGCGC CTGGAGGAGGAGACAGAGTACCTCAACAGCCAGCTAGAGGATGCCATCCGGCTTAAGGAGATCTCTGAAC GGCAGTTGGAGGAGGCGCTGGAGACACTGAAGACAGAGCGGGAGCAGAAGAACAACCTGCGCAAGGAGTT GTCGCACTACATGAGCATCAACGATTCCTTCTATACCAGCCACCTGCAGGTCTCCTTAGATGGCCTCAAG TTCAGTGATGATACTGTCACCGCAGAGCCCAACAATGACGCCGAAGCCCTGGTCAATGGCTTTGAGCACA GTGGCTTGGTCAAATCATCCTTGGACAACAAGACATCCACACCCAGGAAGGATGGCCTAGCTCCACCCTC CCCCAGCCTCGTCTCTGACCTGCTCAGTGAGCTCCACATATCTGAGATCCAGAAGCTGAAACAGCAGCTG GTGCAGATGGAGCGGGAGAAGGTGGGCCTGCTGGCAACACTGCAGGACACACAGAAGCAGCTGGAGCAGG CTCGGGGAACCCTCTCTGAGCAGCATGAGAAGGTGAATCGTCTCACAGAGAACCTTAGTGCCCTCCGGCG CCTGCAGGCTGGCAAGGAGCGACAGACCTCGTTGGATAATGAGAAGGACCGTGACAGCCACGAAGACGGT GACTACTATGAGGTGGACATCAATGGGCCTGAGATCCTGGCCTGCAAGTACCACGTGGCTGTGGCTGAGG CTGGCGAGCTCCGGGAGCAGCTCAAGGCGTTGCGCAGCACACACGAAGCTCGCGAAGCCCAGCACGCAGA AGAAAAGGGCCGGTATGAGGCTGAGGGCCAGGCACTCACTGAGAAGATCTCTCTGCTGGAGAAGGCTAGC CACCAGGACCGAGAGCTGCTGGCCCATCTGGAAAAGGAGCTGAAGAAGGTGAGCGATGTGGCTGGTGAGA CCCAGGGCAGCCTGAATGTGGCTCAGGATGAGCTGGTGACCTTCAGCGAGGAGCTGGCCAACCTCTACCA CCATGTGTGCATGTGCAACAACGAGACGCCCAACCGTGTCATGCTCGACTATTATCGTGAGGGCCAGGGC AAGGCTGGCCGCACCAGCCCAGAGGGCCGCGGGCGCCGGTCACCTGTCCTCTTGCCCAAGGGGCTGTTGG CCACAGAGGTGGGCCGAGCAGATGGTGGGACTGGGGACAACAGTCCTTCACCCAGTTCTTCACTGCCGTC ACCTCTGAGTGACCCCCGCCGGGAACCTATGAACATCTACAACCTGATCGCCATCATCCGAGACCAGATC AAGCACCTGCAGGCAGCCGTGGACCGTACGACCGAGCTGTCCCGGCAGCGGATTGCCTCGCAGGAGCTGG GCCCTGCTGTGGACAAGGACAAGGAAGCACTCATGGAGGAGATCCTCAAGCTGAAGTCCCTGCTGAGTAC CAAGCGGGAGCAGATCACCACACTGCGCACCGTGCTCAAGGCCAACAAGCAGACAGCTGAGGTGGCCCTG GCCAACCTGAAGAGCAAGTATGAGAACGAGAAGGCCATGGTGACCGAGACCATGATGAAGCTACGGAACG AGCTCAAGGCCCTCAAGGAAGACGCAGCCACCTTCTCCTCCCTGCGTGCCATGTTTGCCACCAGGTGTGA CGAATACATCACACAGCTGGATGAGATGCAGCGGCAGCTGGCAGCTGCCGAGGACGAGAAGAAGACCCTT AACTCTCTGTTGCGCATGGCCATCCAGCAGAAGCTGGCGCTCACCCAGCGGCTGGAGCTGCTGGAGCTGG ACCATGAACAGACCCGCAGGGGCCGCAGCAAGGCCGCCTCCAAGGCCAAGCCAGCCTCACCGAGCCTG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR210810 representing NM_001039180
Red=Cloning site Green=Tags(s) MEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTNTQSENERLTS VAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKR LEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNNLRKELSHYMSINDSFYTSHLQVSLDGLK FSDDTVTAEPNNDAEALVNGFEHSGLVKSSLDNKTSTPRKDGLAPPSPSLVSDLLSELHISEIQKLKQQL VQMEREKVGLLATLQDTQKQLEQARGTLSEQHEKVNRLTENLSALRRLQAGKERQTSLDNEKDRDSHEDG DYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKISLLEKAS HQDRELLAHLEKELKKVSDVAGETQGSLNVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQG KAGRTSPEGRGRRSPVLLPKGLLATEVGRADGGTGDNSPSPSSSLPSPLSDPRREPMNIYNLIAIIRDQI KHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVAL ANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTL NSLLRMAIQQKLALTQRLELLELDHEQTRRGRSKAASKAKPASPSL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001039180 |
| ORF Size | 2238 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001039180.2, NP_001034269.1 |
| RefSeq Size | 4555 bp |
| RefSeq ORF | 2241 bp |
| Locus ID | 76895 |
| UniProt ID | Q921C5 |
| MW | 84.7 kDa |
| Gene Summary | Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates and stabilizes the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:11483508, PubMed:25035494, PubMed:24986880, PubMed:22956769). Facilitates the binding of RAB6A to the Golgi by stabilizing its GTP-bound form (PubMed:25962623). Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport via its interaction with RAB6A and recruitment of the dynein-dynactin motor complex (PubMed:12447383, PubMed:25962623). Contributes to nuclear and centrosomal positioning prior to mitotic entry through regulation of both dynein and kinesin-1. During G2 phase of the cell cycle, associates with RANBP2 at the nuclear pores and recruits dynein and dynactin to the nuclear envelope to ensure proper positioning of the nucleus relative to centrosomes prior to the onset of mitosis (PubMed:20386726).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR210810L3 | Lenti ORF clone of Bicd2 (Myc-DDK-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 3 |
CNY 8,460.00 |
|
| MR210810L4 | Lenti ORF clone of Bicd2 (mGFP-tagged) - Mouse bicaudal D homolog 2 (Drosophila) (Bicd2), transcript variant 3 |
CNY 8,460.00 |
