Slc22a6 (NM_008766) Mouse Tagged ORF Clone
CAT#: MR208683
- TrueORF®
Slc22a6 (Myc-DDK-tagged) - Mouse solute carrier family 22 (organic anion transporter), member 6 (Slc22a6)
ORF Plasmid: tGFP
"NM_008766" in other vectors (4)
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CNY 4,064.00
CNY 4,560.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | mOat1; NKT; Oat1; Orctl1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR208683 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCTTCAATGACCTCCTGAAACAGGTGGGGGGTGTCGGACGCTTCCAGCTGATCCAGGTCACCATGG TGGTTGCTCCCCTACTGCTGATGGCTTCCCACAACACCCTGCAGAACTTCACTGCTGCTATCCCCGCTCA CCACTGCCGCCCACCTGCTAATGCCAACCTCAGCAAAGATGGAGGTCTGGAGGCCTGGCTGCCCCTGGAC AAGCAAGGACGACCCGAATCTTGCCTCCGCTTTCCTTTCCCGCACAATGGCACAGAGGCCAATGGCACCG GAGTCACAGAGCCCTGCCTTGATGGCTGGGTCTATGACAACAGCACCTTCCCTTCAACCATCGTGACTGA GTGGAACCTTGTGTGCTCTCATCGGGCCTTCCGCCAGCTGGCCCAGTCCCTGTTCATGGTGGGAGTGTTA CTGGGAGCCATGATGTTTGGCTACCTGGCGGACAGGCTGGGCCGTCGGAAGGTGCTGATCTTGAACTACC TGCAAACAGCTGTGTCGGGAACCTGTGCAGCCTATGCACCCAACTATACTGTCTACTGCATTTTCCGGCT CCTCTCGGGCATGTCTTTGGCTAGCATTGCAATCAACTGCATGACACTAAACATGGAGTGGATGCCTATT CACACCCGTGCCTATGTGGGCACCTTGATTGGCTATGTCTACAGCTTGGGCCAGTTCCTCCTGGCTGGTA TCGCCTATGCTGTGCCCCACTGGCGCCACCTGCAGCTTGCGGTCTCTGTGCCTTTTTTCGTTGCCTTCAT CTACTCTTGGTTCTTCATTGAGTCAGCCCGCTGGTACTCCTCCTCTGGAAGGCTGGACCTCACCCTCCGA GCCCTGCAGAGAGTGGCCCGCATCAACGGGAAACAAGAAGAGGGGGCTAAGCTGAGTATAGAGGTGCTCC AGACCAGCCTGCAGAAGGAACTGACTCTAAACAAAGGCCAGGCCTCCGCCATGGAGCTGCTGCGCTGCCC CACGCTTCGGCGCCTCTTCCTCTGCCTCTCTATGCTGTGGTTTGCCACTAGCTTTGCCTACTACGGGCTG GTCATGGACCTGCAGGGCTTTGGGGTCAGCATGTACCTTATCCAGGTGATTTTCGGCGCTGTGGACCTGC CTGCCAAGTTTGTGTGCTTCCTAGTCATCAATTCCATGGGCCGCCGGCCTGCACAGTTGGCCTCCCTGCT GCTGGCAGGCATCTGTATCCTAGTGAATGGCATAATACCGAGGGGCCATACAATCATTCGCACATCCCTG GCTGTACTAGGGAAAGGCTGTCTGGCTTCCTCTTTCAACTGCATCTTCCTGTACACCGGAGAGCTGTACC CCACAATGATTCGGCAGACGGGCCTGGGCATGGGCAGCACCATGGCCCGGGTGGGCAGCATAGTGAGCCC ACTGATAAGCATGACTGCCGAGTTCTACCCCTCCATACCTCTCTTCATCTTCGGCGCTGTCCCCGTGGCC GCCAGCGCTGTCACTGCCCTGCTGCCAGAGACCTTGGGCCAGCCGCTGCCTGATACAGTGCAGGACCTGA AGAGCAGGAGCAGAGGAAAGCAGAAGCAACAGCAGCTGGAACAGCAGAAGCAGATGATACCACTCCAGGT CTCAACACAAGAGAAGAACGGACTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR208683 protein sequence
Red=Cloning site Green=Tags(s) MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPAHHCRPPANANLSKDGGLEAWLPLD KQGRPESCLRFPFPHNGTEANGTGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVL LGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPI HTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLR ALQRVARINGKQEEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGL VMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPRGHTIIRTSL AVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVA ASAVTALLPETLGQPLPDTVQDLKSRSRGKQKQQQLEQQKQMIPLQVSTQEKNGL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_008766 |
ORF Size | 1638 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_008766.3 |
RefSeq Size | 4026 bp |
RefSeq ORF | 1638 bp |
Locus ID | 18399 |
UniProt ID | Q8VC69 |
MW | 60 kDa |
Gene Summary | Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS), cidofovir, adefovir, 9-(2-phosphonylmethoxyethyl) guanine (PMEG), 9-(2-phosphonylmethoxyethyl) diaminopurine (PMEDAP), ochratoxin (OTA), acyclovir (ACV), 3'-azido-3-'deoxythymidine (AZT), cimetidine (CMD), 2,4-dichloro-phenoxyacetate (2,4-D), hippurate (HA), indoleacetate (IA), indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) and edaravone sulfate (By similarity). Mediates the sodium-independent uptake of p-aminohippurate (PAH). PAH uptake is inhibited by benzothiazolylcysteine (BTC), S-chlorotrifluoroethylcysteine (CTFC), cysteine S-conjugates S-dichlorovinylcysteine (DCVC), furosemide, steviol, phorbol 12-myristate 13-acetate (PMA), calcium ionophore A23187, benzylpenicillin, bumetamide, losartan, probenecid, phenol red, urate, glutarate and alpha-ketoglutarate (By similarity). PAH uptake is inhibited by p-chloromercuribenzenesulphonate (PCMBS), diethyl pyrocarbonate (DEPC), indomethacin, sulindac, diclofenac, carprofen, okadaic acid and PKC activators.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Sex-, Species-, and Tissue-Specific Metabolism of Empagliflozin in Male Mouse Kidney Forms an Unstable Hemiacetal Metabolite (M466/2) That Degrades to 4-Hydroxycrotonaldehyde, a Reactive and Cytotoxic Species
,Taub, ME;Ludwig-Schwellinger, E;Ishiguro, N;Kishimoto, W;Yu, H;Wagner, K;Tweedie, D;,
Chem. Res. Toxicol.
,PubMed ID 25489797
[SLC22A6]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC200825 | Slc22a6 (untagged) - Mouse solute carrier family 22 (organic anion transporter), member 6 (Slc22a6), (10ug) |
CNY 4,064.00 |
|
MG208683 | Slc22a6 (tGFP-tagged) - Mouse solute carrier family 22 (organic anion transporter), member 6 (Slc22a6) |
CNY 5,040.00 |
|
MR208683L3 | Lenti ORF clone of Slc22a6 (Myc-DDK-tagged) - Mouse solute carrier family 22 (organic anion transporter), member 6 (Slc22a6) |
CNY 6,460.00 |
|
MR208683L4 | Lenti ORF clone of Slc22a6 (mGFP-tagged) - Mouse solute carrier family 22 (organic anion transporter), member 6 (Slc22a6) |
CNY 6,464.00 |
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