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Tbxas1 (NM_011539) Mouse Tagged ORF Clone
CAT＃: MR208546
- TrueORF®
Tbxas1 (Myc-DDK-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1)
ORF Plasmid: tGFP
"NM_011539" in other vectors (4)
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CNY 3,976.00
CNY 4,560.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CYP5; CYP5A1; THAS; TS; TXAS; TXS |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR208546 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAAGTGTTGGGGCTTCTCAAGTTTGAAGTCAGTGGTACCATAGTGACTGTGACTCTGCTCGTGGCTC TCTTGGCCCTCCTGAAATGGTACTCCATGTCAGCTTTCTCAAGACTGGAGAAGTTGGGCATCAGGCACCC CAAGCCTTCTCCTTTTGTTGGAAACTTGATGTTTTTCCGCCAGGGTTTTTGGGAGAGCCAATTGGAACTC CGAGAGCGATACGGGCCTCTGTGTGGGTACTATCTTGGCCGTCGGATGCACGTTGTCATTTCAGAGCCAG ACATGATCAAGCAGGTGTTGGTTGAGAACTTCAGTAACTTTTCCAACAGAATGGCCTCAGGTCTGGAACC CAAGATGGTAGCAGACAGTGTCCTGTTGTTACGTGACAGAAGATGGGAGGAAGTCAGGGGTGCCCTGATG TCTTCATTCAGTCCTGAAAAGTTGGATGAGATGACACCTCTCATCAGCCAAGCCTGTGAACTTCTCATGG CTCACTTAAAACGCTATGCAGCATCCAGGGACGCATTCAACATCCAGAGGTGTTACTGCTGTTACACCAT AGATGTGGTGGCCAGTGTGGCCTTTGGCACCCAGGTGGACTCCCAGAATTCTCCAGAAGATCCCTTTGTG CAACACTGCCGGCGTGCTTCCACCTTCTGTATCCCCAGGCCTCTCCTGGTATTAATCTTATCATTTCCAT CCATAATGGTCCCATTGGCCCGGATTCTGCCCAATAAGAACCGAGATGAACTGAATGGCTTTTTTAACAC ACTCATTAGGAATGTGATTGCCTTACGGGACCAGCAAGCAGCAGAAGAGAGGCGGAGAGACTTCCTGCAG ATGGTGCTGGATGCCCAGCACTCCATGAACTCTGTGGGCGTGGAAGGCTTTGACATGGTCCCAGAATCCC TGTCCTCTTCTGAGTGCACAAAGGAACCACCCCAAAGGTGCCATCCTACCTCCACATCTAAGCCTTTCAC TGTGGATGAAATTGTGGGCCAGGCCTTCCTCTTCCTCATTGCGGGCCATGAGGTCATCACAAACACGCTG TCCTTCATCACATACCTGCTGGCCACCCACCCTGACTGCCAGGAGAGGCTTCTGAAAGAGGTGGACCTCT TCATGGGGAAGCACCCAGCCCCTGAGTACCACAGCCTGCAGGAAGGTCTGCCGTATCTGGACATGGTGAT TTCAGAGACCCTGAGGATGTACCCACCAGCTTTCAGGTTCACACGGGAGGCAGCACAGGACTGTGAGGTG CTGGGACAACGTATCCCTGCAGGTGCAGTGCTGGAGATAGCTGTGGGTGCCTTACACCATGACCCAGAGC ACTGGCCGAATCCTGAGACCTTTGACCCTGAAAGGTTCACAGCAGAGGCCCGGCTTCAGCGGAGGCCGTT CACATACCTGCCCTTTGGAGCTGGCCCCAGGAGCTGCCTCGGAGTGCGGCTGGGCCTGCTGGTGGTCAAG CTGACAATACTCCAGGTCCTACACAAGTTCCGCTTTGAAGCCAGCCCTGAGACTCAGGTTCCACTTCAGC TAGAATCCAAATCTGCCCTAGGCCCCAAAAATGGAGTCTACATCAAGATTGTGTCACGC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR208546 protein sequence
Red=Cloning site Green=Tags(s) MEVLGLLKFEVSGTIVTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFRQGFWESQLEL RERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLRDRRWEEVRGALM SSFSPEKLDEMTPLISQACELLMAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFGTQVDSQNSPEDPFV QHCRRASTFCIPRPLLVLILSFPSIMVPLARILPNKNRDELNGFFNTLIRNVIALRDQQAAEERRRDFLQ MVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTL SFITYLLATHPDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEV LGQRIPAGAVLEIAVGALHHDPEHWPNPETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVK LTILQVLHKFRFEASPETQVPLQLESKSALGPKNGVYIKIVSR TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_011539 |
| ORF Size | 1602 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_011539.2 |
| RefSeq Size | 1992 bp |
| RefSeq ORF | 1602 bp |
| Locus ID | 21391 |
| UniProt ID | P36423 |
| MW | 60.4 kDa |
| Gene Summary | Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC217547 | Tbxas1 (untagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1), (10ug) |
CNY 6,840.00 |
|
| MG208546 | Tbxas1 (tGFP-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1) |
CNY 5,040.00 |
|
| MR208546L3 | Lenti ORF clone of Tbxas1 (Myc-DDK-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1) |
CNY 6,460.00 |
|
| MR208546L4 | Lenti ORF clone of Tbxas1 (mGFP-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1) |
CNY 6,460.00 |
