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Tbxas1 (NM_011539) Mouse Untagged Clone
CAT＃: MC217547
Tbxas1 (untagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1), (10ug)
CNY 6,840.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | CYP5; CYP5A1; THAS; TS; TXAS; TXS |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC217547 representing NM_011539
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAAGTGTTGGGGCTTCTCAAGTTTGAAGTCAGTGGTACCATAGTGACTGTGACTCTGCTCGTGGCTC TCTTGGCCCTCCTGAAATGGTACTCCATGTCAGCTTTCTCAAGACTGGAGAAGTTGGGCATCAGGCACCC CAAGCCTTCTCCTTTTGTTGGAAACTTGATGTTTTTCCGCCAGGGTTTTTGGGAGAGCCAATTGGAACTC CGAGAGCGATACGGGCCTCTGTGTGGGTACTATCTTGGCCGTCGGATGCACGTTGTCATTTCAGAGCCAG ACATGATCAAGCAGGTGTTGGTTGAGAACTTCAGTAACTTTTCCAACAGAATGGCCTCAGGTCTGGAACC CAAGATGGTAGCAGACAGTGTCCTGTTGTTACGTGACAGAAGATGGGAGGAAGTCAGGGGTGCCCTGATG TCTTCATTCAGTCCTGAAAAGTTGGATGAGATGACACCTCTCATCAGCCAAGCCTGTGAACTTCTCGTGG CTCACTTAAAACGCTATGCAGCATCCAGGGACGCATTCAACATCCAGAGGTGTTACTGCTGTTACACCAT AGATGTGGTGGCCAGTGTGGCCTTTGGCACCCAGGTGGACTCCCAGAATTCTCCAGAAGATCCCTTTGTG CAACACTGCCGGCGTGCTTCCACCTTCTGTATCCCCAGGCCTCTCCTGGTATTAATCTTATCATTTCCAT CCATAATGGTCCCATTGGCCCGGATTCTGCCCAATAAGAACCGAGATGAACTGAATGGCTTTTTTAACAC ACTCATTAGGAATGTGATTGCCTTACGGGACCAGCAAGCAGCAGAAGAGAGGCGGAGAGACTTCCTGCAG ATGGTGCTGGATGCCCAGCACTCCATGAACTCTGTGGGCGTGGAAGGCTTTGACATGGTCCCAGAATCCC TGTCCTCTTCTGAGTGCACAAAGGAACCACCCCAAAGGTGCCATCCTACCTCCACATCTAAGCCTTTCAC TGTGGATGAAATTGTGGGCCAGGCCTTCCTCTTCCTCATTGCGGGCCATGAGGTCATCACAAACACGCTG TCCTTCATCACATACCTGCTGGCCACCCACCCTGACTGCCAGGAGAGGCTTCTGAAAGAGGTGGACCTCT TCATGGGGAAGCACCCAGCCCCTGAGTACCACAGCCTGCAGGAAGGTCTGCCGTATCTGGACATGGTGAT TTCAGAGACCCTGAGGATGTACCCACCAGCTTTCAGGTTCACACGGGAGGCAGCACAGGACTGTGAGGTG CTGGGACAACGTATCCCTGCAGGTACAGTGCTGGAGATAGCTGTGGGTGCCCTACACCATGACCCAGAGC ACTGGCCGAATCCTGAGACCTTTGACCCTGAAAGGTTCACAGCAGAGGCCCGGCTTCAGCGGAGGCCGTT CACATACCTGCCCTTTGGAGCTGGCCCCAGGAGCTGCCTCGGAGTGCGGCTGGGCCTGCTGGTGGTCAAG CTGACAATACTCCAGGTCCTACACAAGTTCCGCTTTGAAGCCAGCCCTGAGACTCAGGTTCCACTTCAGC TAGAATCCAAATCTGCCCTAGGCCCCAAAAATGGAGTCTACATCAAGATTGTGTCACGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011539 |
| Insert Size | 1602 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_011539.3, NP_035669.3 |
| RefSeq Size | 1992 bp |
| RefSeq ORF | 1602 bp |
| Locus ID | 21391 |
| UniProt ID | P36423 |
| Gene Summary | Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation. Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage. 12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2. Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG208546 | Tbxas1 (tGFP-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1) |
CNY 5,040.00 |
|
| MR208546 | Tbxas1 (Myc-DDK-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1) |
CNY 3,976.00 |
|
| MR208546L3 | Lenti ORF clone of Tbxas1 (Myc-DDK-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1) |
CNY 6,460.00 |
|
| MR208546L4 | Lenti ORF clone of Tbxas1 (mGFP-tagged) - Mouse thromboxane A synthase 1, platelet (Tbxas1) |
CNY 6,460.00 |
