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Mapk8ip3 (NM_001163448) Mouse Tagged ORF Clone
CAT＃: MG223075
- TrueORF®
Mapk8ip3 (tGFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3) transcript variant 3, (10ug)
ORF Plasmid: DDK
"NM_001163448" in other vectors (4)
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CNY 14,540.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | BB120594; D17Wsu15e; JIP-3; Jip3; JSAP1; JSAP1a; JSAP1b; JSAP1c; JSAP1d; mKIAA1066; Syd2 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG223075 representing NM_001163448
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATGGAGATCCAGATGGACGAGGGAGGAGGAGTGGTGGTGTACCAAGACGACTACTGCTCGGGCTCGG TCATGTCGGAGCGTGTGTCGGGCCTGGCGGGCTCCATCTACCGCGAGTTCGAGCGCCTCATTCACTGCTA TGACGAGGAGGTGGTCAAGGAGCTCATGCCGCTGGTGGTGAACGTGCTGGAGAACCTTGACTCGGTGCTG AGCGAGAACCAGGAGCACGAGGTGGAGCTGGAGCTCCTACGCGAGGACAACGAGCAGCTGCTCACGCAAT ACGAGCGCGAGAAGGCGCTGCGCAAACAGGCCGAGGAGAAATTCATCGAATTTGAAGATGCCTTGGAACA AGAGAAGAAAGAACTCCAGATCCAGGTAGAACATTATGAGTTTCAGACACGCCAGCTGGAGCTAAAGGCC AAAAACTATGCAGATCAGATTTCCCGACTGGAGGAACGAGAATCGGAGATGAAGAAGGAATACAATGCCC TGCACCAGCGGCACACAGAGATGATCCAGACCTATGTGGAACACATTGAAAGATCCAAGATGCAGCAAGT TGGGGGTAGCGGCCAAACAGAAAGCAGCCTGCCCGGGCGGAGCAGGAAGGAGCGTCCCACCTCTCTGAAT GTCTTCCCCCTGGCTGATGGCATGGTACGTGCACAGATGGGGGGCAAGCTCGTGCCTGCGGGGGACCACT GGCACCTGAGTGACCTCGGCCAGCTACAGTCCAGCTCCAGCTACCAGTGTCCAAATGATGAGATGTCTGA GTCAGGCCAGTCCTCAGCAGCTGCAACACCCAGTACCACAGGTACCAAGTCCAACACACCCACGTCCTCC GTGCCCTCAGCAGCAGTCACGCCACTCAACGAGAGCCTACAGCCCCTGGGGGACTATGTCAGTGTCACAA AGAACAACAAGCAGGCCCGAGAGAAGCGCAATAGCCGTAACATGGAGGTCCAGGTCACCCAAGAGATGCG GAACGTCAGTATCGGCATGGGCAGCAGTGACGAGTGGTCCGATGTTCAGGACATTATCGACTCCACCCCA GAGCTGGATGTGTGTCCTGAAACCCGTCTGGAGCGCACAGGAAGCAGCCCAACCCAGGGAATTGTAAACA AAGCTTTTGGAATCAACACTGACTCCTTGTATCACGAACTCTCCACGGCGGGATCTGAGGTCATCGGGGA TGTGGACGAGGGAGCTGATCTCCTAGGGGAGTTTTCAGGAATGGGCAAAGAAGTGGGGAACCTGCTGCTG GAGAACTCACAGCTTCTAGAGACAAAAAATGCTTTAAATGTAGTGAAGAATGACCTCATTGCTAAGGTTG ACCAACTGTCAGGAGAACAGGAGGTCCTGAAGGGTGAGCTGGAAGCAGCCAAGCAAGCCAAAGTCAAGCT GGAGAACCGAATCAAAGAGCTTGAAGAAGAACTGAAGAGAGTCAAGTCAGAGGCAGTAACTGCCCGCCGT GAGCCCAGAGAAGAGGTGGAGGATGACAAAATCCCCATGGCCCAGCGCCGACGCTTCACACGGGTGGAGA TGGCCCGAGTGCTCATGGAACGCAACCAGTACAAGGAACGCCTCATGGAGCTGCAGGAGGCTGTGAGGTG GACTGAAATGATCAGAGCATCAAGGGAACACCCATCTGTCCAGGAGAAGAAGAAGTCCACCATCTGGCAG TTCTTTAGTCGCCTCTTCAGCTCCTCATCTAGCCCCCCTCCGGCCAAACGATCCTACCCATCTGTGAACA TTCACTACAAGTCACCCACTGCAGCTGGCTTTAGCCAGCGTCGCAGCCATGCTTTGTGCCAGATCTCAGC CGGCAGCAGGCCCCTGGAGTTCTTCCCTGATGATGACTGCACCTCTTCTGCCCGGCGGGAGCAGAAGCGG GAGCAGTACCGCCAGGTTCGTGAACACGTGCGCAATGATGACGGGAGGCTGCAGGCCTGTGGGTGGAGCC TGCCTGCCAAGTACAAGCAGCTGAGCCCCAATGGAGGCCAGGAAGACACCCGGATGAAAAATGTGCCTGT CCCTGTGTACTGCCGCCCTCTGGTGGAGAAGGACCCTTCGACAAAGCTGTGGTGTGCTGCTGGTGTCAAC CTGAGTGGGTGGAAGCCACATGAAGAGGACTCTAGCAATGGACCCAAGCCTGTACCAGGTCGAGACCCTC TGACCTGTGACCGGGAAGGAGAAGGCGAACCCAAGAGCACACACCCATCACCTGAGAAGAAGAAGGCAAA GGAAACCCCTGAGGCAGATGCTACCTCCAGTCGGGTATGGATCCTCACCAGCACCCTGACAACCAGCAAG GTGGTGATCATTGATGCCAACCAGCCAGGCACAATTGTGGATCAGTTCACAGTCTGCAATGCCCACGTCC TGTGTATCTCCAGCATTCCTGCGGCCAGTGACAGTGACTATCCCCCTGGGGAGATGTTCCTAGACAGTGA TGTGAACCCTGAAGATTCAGGTGCTGATGGTGTGCTGGCTGGCATCACCCTGGTGGGGTGTGCTACCCGC TGCAATGTTCCACGTAGCAACTGTTCCTCACGAGGAGACACCCCAGTACTGGACAAGGGGCAGGGGGATG TGGCGACCACTGCCAATGGGAAGGTCAACCCGTCCCAATCCACAGAAGAAGCCACAGAAGCCACGGAGGT GCCAGACCCTGGTCCCAGCGAGTCAGAAGCAACGACAGTCCGGCCCGGGCCTCTCACAGAGCATGTCTTT ACTGACCCAGCACCCACCCCATCCTCCAGCACCCAGCCTGCCAGTGAGAATGGGTCAGAGTCCAATGGCA CCATTGTACAGCCTCAGGTGGAGCCCAGTGGGGAACTCTCAACAACAACCAGTAGCGCTGCACCCACTAT GTGGCTAGGAGCCCAGAATGGCTGGCTCTATGTGCATTCAGCGGTAGCCAACTGGAAGAAGTGTCTGCAC TCCATCAAGCTAAAAGACTCTGTGCTGAGCCTGGTGCATGTCAAAGGCCGAGTGCTGGTAGCTCTTGCAG ATGGGACCCTGGCTATCTTCCATCGTGGAGAGGATGGCCAGTGGGACCTGAGCAACTACCACCTAATGGA CCTGGGCCACCCACACCACTCCATCCGCTGCATGGCTGTTGTGAATGACCGAGTTTGGTGTGGCTACAAG AACAAGGTGCATGTTATCCAGCCCAAGACAATGCAGATTGAGAAATCATTTGATGCCCACCCAAGGCGGG AAAGCCAGGTACGTCAGCTGGCCTGGATCGGTGATGGAGTGTGGGTCTCTATTCGCTTGGATTCTACCCT TCGGCTCTACCATGCTCACACCCACCAGCACCTGCAGGATGTGGACATTGAGCCCTATGTTAGCAAGATG CTAGGAACCGGCAAGCTGGGCTTCTCCTTCGTGCGCATCACAGCCTTACTCATTGCAGGCAACCGTCTGT GGGTGGGCACTGGCAATGGGGTTGTCATCTCCATCCCCTTGACTGAGACTGTGGTCCTGCATCGAGGCCA GCTCCTAGGGCTCCGAGCCAACAAGACATCCCCAACATCTGGGGAGGGGACCCGCCCAGGGGGCATCATC CATGTGTATGGGGACGACAGCAGTGACAAGGCCGCCAGTAGTTTCATCCCCTACTGCTCCATGGCACAGG CTCAGCTTTGCTTCCATGGGCACCGTGATGCTGTCAAATTCTTTGTCTCTGTGCCAGGAAATGTGCTGGC CACTCTCAATGGCAGTGTGCTAGACAGCCCATCAGAGGGCCCTGGGCCTGCTGCACCCGCTGCAGATGCT GAGGGCCAGAAGTTGAAGAATGCACTGGTGCTGAGTGGTGGTGAAGGTTACATTGACTTCCGTATCGGAG ACGGAGAGGATGATGAAACTGAGGAATGTGCCGGGGACGTGAACCAGACAAAGCCCTCGTTGTCCAAGGC TGAGCGCAGCCACATCATCGTGTGGCAGGTGTCCTACACCCCTGAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG223075 representing NM_001163448
Red=Cloning site Green=Tags(s) MMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENLDSVL SENQEHEVELELLREDNEQLLTQYEREKALRKQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKA KNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGSGQTESSLPGRSRKERPTSLN VFPLADGMVRAQMGGKLVPAGDHWHLSDLGQLQSSSSYQCPNDEMSESGQSSAAATPSTTGTKSNTPTSS VPSAAVTPLNESLQPLGDYVSVTKNNKQAREKRNSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTP ELDVCPETRLERTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSGMGKEVGNLLL ENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLKGELEAAKQAKVKLENRIKELEEELKRVKSEAVTARR EPREEVEDDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQ FFSRLFSSSSSPPPAKRSYPSVNIHYKSPTAAGFSQRRSHALCQISAGSRPLEFFPDDDCTSSARREQKR EQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQEDTRMKNVPVPVYCRPLVEKDPSTKLWCAAGVN LSGWKPHEEDSSNGPKPVPGRDPLTCDREGEGEPKSTHPSPEKKKAKETPEADATSSRVWILTSTLTTSK VVIIDANQPGTIVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDSGADGVLAGITLVGCATR CNVPRSNCSSRGDTPVLDKGQGDVATTANGKVNPSQSTEEATEATEVPDPGPSESEATTVRPGPLTEHVF TDPAPTPSSSTQPASENGSESNGTIVQPQVEPSGELSTTTSSAAPTMWLGAQNGWLYVHSAVANWKKCLH SIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVNDRVWCGYK NKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKM LGTGKLGFSFVRITALLIAGNRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGTRPGGII HVYGDDSSDKAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDSPSEGPGPAAPAADA EGQKLKNALVLSGGEGYIDFRIGDGEDDETEECAGDVNQTKPSLSKAERSHIIVWQVSYTPE TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001163448 |
| ORF Size | 3966 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001163448.1, NP_001156920.1 |
| RefSeq Size | 5551 bp |
| RefSeq ORF | 3969 bp |
| Locus ID | 30957 |
| UniProt ID | Q9ESN9 |
| Gene Summary | The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (PubMed:10523642, PubMed:10629060). Promotes neuronal axon elongation in a kinesin- and JNK-dependent manner (PubMed:23576431, PubMed:25944905, PubMed:28259553). Activates cofilin at axon tips via local activation of JNK, thereby regulating filopodial dynamics and enhancing axon elongation (PubMed:23576431, PubMed:25944905, PubMed:28259553). Its binding to kinesin heavy chains (KHC), promotes kinesin-1 motility along microtubules and is essential for axon elongation and regeneration (PubMed:23576431, PubMed:25944905, PubMed:28259553). Regulates cortical neuronal migration by mediating NTRK2/TRKB anterograde axonal transport during brain development (PubMed:23576431, PubMed:25944905, PubMed:28259553). Acts as an adapter that bridges the interaction between NTRK2/TRKB and KLC1 and drives NTRK2/TRKB axonal but not dendritic anterograde transport, which is essential for subsequent BDNF-triggered signaling and filopodia formation (PubMed:23576431, PubMed:25944905, PubMed:28259553).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC224236 | Mapk8ip3 (untagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3, (10ug) |
CNY 17,010.00 |
|
| MR223075 | Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3 |
CNY 13,210.00 |
|
| MR223075L3 | Lenti ORF clone of Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3 |
CNY 15,110.00 |
|
| MR223075L4 | Lenti ORF clone of Mapk8ip3 (mGFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 3 |
CNY 15,110.00 |
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