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Zfand2b (NM_026846) Mouse Tagged ORF Clone
CAT＃: MG219158
- TrueORF®
Zfand2b (tGFP-tagged) - Mouse zinc finger AN1 type domain 2B (Zfand2b) transcript variant 1, (10ug)
ORF Plasmid: DDK
"NM_026846" in other vectors (5)
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CNY 2,850.00
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Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | 1110060O18Rik; C81256 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG219158 representing NM_026846
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGTTTCCGGACCTCGGGGCTCACTGTTCCGAGCCGAGCTGTCAGCGCTTGGATTTTTTGCCACTCA AGTGCGATGCCTGCTCGGGCATCTTCTGCGCAGACCATGTGGCCTACGCCCAGCATCACTGTGGATCAGC TTACCAAAAGGATATCCAGGTACCTGTGTGCCCTCTCTGTAATGTGCCTGTGCCGGTGGCCAGAGGAGAG CCTCCTGACCGTGCTGTGGGAGAGCACATTGACAGAGACTGTCGTTCTGACCCAGCACAGCAAAAACGCA AGATCTTCACCAATAAGTGTGAACGTTCTGGCTGCCGGCAGCGGGAGATGATGAAACTGACTTGTGATCG CTGTGGCCGAAACTTCTGCATCAAGCACCGTCATCCCCTGGACCATGAATGCTCTGGGGAAGGTCATCAG ACCAGCAGGGCAGGGCTTGCTGCTATTTCTAGAGCACAAGGTCTGGCTTCTACAAGCACCGCCCCCAGTC CAAGCCGGACCTTGCCTTCATCATCCTCCCCAAGCAGAGCTACACCCCAGCTTCCAACCAGGACAGCCTC TCCTGTTATTGCTTTGCAGAATGGCTTGAGTGAGGATGAGGCCCTGCAGCGTGCCCTGGAACTGTCCCTT GCGGAGGCTAAACCCCAGGTTCTAAGTTCTCAGGAGGAAGACGACTTGGCGTTAGCACAGGCACTGTCAG CCAGTGAGGCAGAATACCAACAGCAGCAGGCGCAGAGTCGTAGCTTGAAGCCGTCCAACTGCAGCCTGTG C ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG219158 representing NM_026846
Red=Cloning site Green=Tags(s) MEFPDLGAHCSEPSCQRLDFLPLKCDACSGIFCADHVAYAQHHCGSAYQKDIQVPVCPLCNVPVPVARGE PPDRAVGEHIDRDCRSDPAQQKRKIFTNKCERSGCRQREMMKLTCDRCGRNFCIKHRHPLDHECSGEGHQ TSRAGLAAISRAQGLASTSTAPSPSRTLPSSSSPSRATPQLPTRTASPVIALQNGLSEDEALQRALELSL AEAKPQVLSSQEEDDLALAQALSASEAEYQQQQAQSRSLKPSNCSLC TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_026846 |
| ORF Size | 771 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_026846.3, NP_081122.2 |
| RefSeq Size | 1240 bp |
| RefSeq ORF | 774 bp |
| Locus ID | 68818 |
| UniProt ID | Q91X58 |
| Gene Summary | Plays a role in protein homeostasis by regulating both the translocation and the ubiquitin-mediated proteasomal degradation of nascent proteins at the endoplasmic reticulum (PubMed:24160817, PubMed:26337389, PubMed:26692333). It is involved in the regulation of signal-mediated translocation of proteins into the endoplasmic reticulum (PubMed:24160817). It also plays a role in the ubiquitin-mediated proteasomal degradation of proteins for which signal-mediated translocation to the endoplasmic reticulum has failed (PubMed:18467495, PubMed:26337389). May therefore function in the endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation (PubMed:24160817, PubMed:26337389). By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway (PubMed:26692333).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC201128 | Zfand2b (untagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1, (10ug) |
CNY 2,400.00 |
|
| MG203320 | Zfand2b (tGFP-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b) |
CNY 2,850.00 |
|
| MR219158 | Zfand2b (Myc-DDK-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1 |
CNY 2,400.00 |
|
| MR219158L3 | Lenti ORF clone of Zfand2b (Myc-DDK-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1 |
CNY 4,750.00 |
|
| MR219158L4 | Lenti ORF clone of Zfand2b (mGFP-tagged) - Mouse zinc finger, AN1 type domain 2B (Zfand2b), transcript variant 1 |
CNY 4,750.00 |
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