Cavin2 (NM_138741) Mouse Tagged ORF Clone
CAT#: MG206626
- TrueORF®
Sdpr (tGFP-tagged) - Mouse serum deprivation response (Sdpr)
ORF Plasmid: DDK
"NM_138741" in other vectors (4)
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CNY 3,710.00
Cited in 1 publication. |
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | Sdpr |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MG206626 representing NM_138741
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGAGAGGACGCTGCACAGGCAGAAAAGTTCCAGCATCCAAACACAGACATGCTCCAGGAGAAGCCAT CCAGCCCCAGCCCAATGCCTTCCTCCACACCGAGCCCCAGCCTGAACCTGGGGTCCACAGAGGAGGCCAT CCGAGACAACTCGCAGGTGAATGCTGTCACCGTGCACACACTCCTGGATAAATTGGTCAACATGCTGGAC GCCGTGAGGGAGAACCAGCACAACATGGAACAGCGTCAGATCAACCTGGAGGGCTCGGTGAAGGGCATCC AGAACGACCTCACCAAGCTCTCCAAGTACCAGGCCTCCACCAGCAACACAGTGAGCAAGCTGCTAGAGAA GTCTCGCAAGGTCAGCGCTCACACGCGGGCTGTCCGGGAGCGCCTCGAGAGGCAGTGTGTCCAGGTGAAG AGACTGGAGAACAACCACGCCCAACTCCTCCGACGCAACCACTTCAAAGTGCTCATCTTCCAGGAAGAAA GTGAGATCCCTGCCAGTGTGTTTGTGAAGGAGCCAGTTCCCAGCGCTGCAGAAGGCAAGGAGGAGCTTGC TGATGAGAACAAGTCCCTGGAGGAAACTCTGCACAACGTGGACCTCTCCTCTGATGACGAATTGCCCCGT GATGAGGAAGCCCTGGAAGATAGTGCAGAAGAGAAGATGGAAGAAAGCAGGGCAGAAAAAATAAAAAGAT CCAGCCTCAAGAAAGTCGATAGCCTCAAGAAAGCGTTTTCTCGTCAGAACATCGAGAAAAAGATGAACAA GCTGGGAACCAAGATCGTATCTGTTGAGAGGAGAGAAAAGATTAAGAAATCGCTCACACCCAACCACCAG AAAGCATCTTCTGGGAAAAGCTCCCCCTTCAAGGTTTCTCCCCTCTCCTTTGGTCGTAAGAAAGTCCGAG AGGGAGAAAGCTCTGTAGAAAATGAGACCAAGTTGGAAGACCAGATGCAGGAGGACCGCGAGGAGGGTTC GTTCACAGAGGGTCTTTCTGAAGCATCCCTCCCCAGTGGCCTGATGGAGGGCAGCGCAGAAGATGCTGAG AAATCAGCAAGGAGAGGGAACAACTCAGCCGTGGGCAGTAATGCGGATCTGACCATTGAGGAAGATGAAG AAGAGGAGCCGGTAGCCCTGCAGCAGGCCCAGCAGGTGCGCTATGAGAGTGGCTACATGCTCAACTCCGA GGAGATGGAGGAACCCAGTGAGAAACAGGTCCAGCCAGCTGTGCTGCATGTGGATCAGACTGCC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG206626 representing NM_138741
Red=Cloning site Green=Tags(s) MGEDAAQAEKFQHPNTDMLQEKPSSPSPMPSSTPSPSLNLGSTEEAIRDNSQVNAVTVHTLLDKLVNMLD AVRENQHNMEQRQINLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVRERLERQCVQVK RLENNHAQLLRRNHFKVLIFQEESEIPASVFVKEPVPSAAEGKEELADENKSLEETLHNVDLSSDDELPR DEEALEDSAEEKMEESRAEKIKRSSLKKVDSLKKAFSRQNIEKKMNKLGTKIVSVERREKIKKSLTPNHQ KASSGKSSPFKVSPLSFGRKKVREGESSVENETKLEDQMQEDREEGSFTEGLSEASLPSGLMEGSAEDAE KSARRGNNSAVGSNADLTIEEDEEEEPVALQQAQQVRYESGYMLNSEEMEEPSEKQVQPAVLHVDQTA TRTRPLE - GFP Tag - V |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_138741 |
ORF Size | 1254 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_138741.1, NP_620080.1 |
RefSeq Size | 3069 bp |
RefSeq ORF | 1257 bp |
Locus ID | 20324 |
UniProt ID | Q63918 |
Gene Summary | Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae (By similarity). Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells (PubMed:23652019). May play a role in targeting PRKCA to caveolae (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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CAVIN2 is frequently silenced by CpG methylation and sensitizes lung cancer cells to paclitaxel and 5-FU.
,null,
Epigenomics
,PubMed ID 33016107
[Cavin2]
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Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC205795 | Sdpr (untagged) - Mouse serum deprivation response (Sdpr), (10ug) |
CNY 3,656.00 |
|
MR206626 | Sdpr (Myc-DDK-tagged) - Mouse serum deprivation response (Sdpr) |
CNY 3,656.00 |
|
MR206626L3 | Lenti ORF clone of Sdpr (Myc-DDK-tagged) - Mouse serum deprivation response (Sdpr) |
CNY 5,230.00 |
|
MR206626L4 | Lenti ORF clone of Sdpr (mGFP-tagged) - Mouse serum deprivation response (Sdpr) |
CNY 5,230.00 |