Flna (NM_001290421) Mouse Untagged Clone

CAT#: MC229690

Flna (untagged) - Mouse filamin, alpha (Flna), transcript variant 2



  "NM_001290421" in other vectors (1)

CNY 19,100.00


货期*
8周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms ABP-280; Dilp2; F730004A14Rik; filamin-1; Fln1; GENA 379
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC229690 representing NM_001290421
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCTGACATCCGTGAGGCACCCCAGGATTTTCACCCAGACAGGGTGAAGGCACGTGGGCCTGGATTGG
AGAAGACTGGTGTGGCTGTCAACAAGCCAGCAGAGTTCACAGTTGATGCCAAGCATGCTGGGAAGGCTCC
TCTTCGAGTTCAAGTTCAGGACAATGAGGGCTGCTCTGTGGAAGCGACAGTCAAGGACAATGGCAATGGT
ACTTACAGCTGTTCTTATGTGCCCAGAAAGCCAGTGAAGCACACAGCCATGGTTTCTTGGGGAGGTGTCA
GCATCCCCAACAGTCCTTTCCGGGTGAATGTGGGAGCTGGCAGCCATCCAAACAAAGTCAAGGTGTATGG
TCCAGGAGTGGCCAAGACTGGGCTCAAGGCCCATGAACCTACCTACTTTACTGTGGATTGTACTGAAGCT
GGCCAGGGAGATGTCAGCATTGGTATCAAGTGTGCCCCTGGAGTAGTGGGCCCCACTGAGGCTGATATTG
ACTTTGATATCATCCGCAATGACAATGACACCTTCACTGTAAAATACACACCCTGTGGGGCTGGCAGCTA
TACCATCATGGTCCTTTTTGCTGACCAGGCCACACCCACCAGCCCCATCAGAGTCAAAGTGGAGCCTTCT
CATGATGCCAGCAAGGTGAAGGCTGAGGGTCCTGGCCTAAATCGCACTGGTGTTGAACTTGGCAAACCCA
CCCATTTCACAGTCAATGCTAAAACTGCTGGGAAAGGCAAGCTGGATGTCCAATTCTCAGGACTGGCTAA
GGGAGATGCAGTACGGGATGTGGACATCATTGACCACCATGATAATACCTACACAGTCAAGTACATTCCT
GTGCAGCAGGGCCCAGTAGGTGTCAATGTCACTTATGGAGGAGATCACATCCCCAAGAGTCCATTTTCAG
TGGGAGTATCTCCAAGCCTGGATCTCAGCAAAATCAAGGTGTCTGGCCTTGGTGACAAAGTGGACGTTGG
CAAAGATCAAGAGTTCACAGTAAAGTCAAAGGGTGCAGGTGGTCAAGGCAAAGTAGCATCCAAGATTGTG
AGTCCCTCAGGTGCAGCGGTACCCTGCAAGGTAGAGCCAGGCCTGGGAGCTGACAACAGCGTGGTACGTT
TTGTGCCCCGTGAAGAGGGGCCCTATGAGGTGGAAGTGACCTATGATGGTGTGCCTGTACCTGGCAGTCC
CTTTCCACTAGAAGCTGTGGCCCCCACCAAACCCAGCAAGGTGAAGGCGTTTGGACCAGGGCTACAGGGG
GGCAATGCAGGCTCCCCTGCCCGCTTCACCATTGATACAAAGGGTGCTGGCACTGGTGGCCTGGGCCTGA
CAGTGGAAGGCCCCTGTGAAGCACAGCTTGAGTGCCTAGACAACGGGGATGGTACATGCTCTGTGTCTTA
TGTACCCACTGAGCCTGGGGACTACAACATCAACATCCTTTTTGCTGACACCCACATTCCTGGATCCCCA
TTCAAGGCCCATGTGGCTCCTTGTTTTGATGCATCCAAGGTGAAGTGCTCAGGCCCTGGGCTGGAGCGGG
CTACTGCTGGTGAGGTAGGGCAGTTCCAAGTGGACTGTTCAAGTGCTGGCAGTGCTGAGTTGACGATTGA
GATCTGCTCTGAGGCAGGACTGCCAGCTGAAGTATACATTCAAGACCATGGTGATGGCACACACACCATT
ACCTATATTCCTCTCTGTCCTGGGGCTTACACTGTTACCATCAAGTATGGCGGCCAGCCTGTGCCCAACT
TCCCCAGCAAGCTACAGGTGGAACCTGCTGTAGATACCTCAGGTGTACAGTGCTATGGGCCTGGGATTGA
AGGTCAAGGTGTCTTCCGAGAGGCAACCACTGAGTTCAGTGTGGATGCCCGGGCTCTTACACAGACTGGA
GGGCCACATGTCAAGGCTCGAGTGGCCAACCCCTCAGGCAATCTGACAGATACCTATGTGCAAGACTGTG
GGGATGGCACATACAAAGTGGAATACACTCCATATGAGGAAGGAGTACACTCTGTGGATGTGACTTATGA
TGGCAGCCCTGTGCCCAGCAGCCCCTTCCAGGTGCCTGTAACAGAGGGCTGTGACCCCTCCCGGGTGCGT
GTCCATGGACCAGGCATCCAAAGTGGTACCACCAACAAACCCAACAAGTTCACAGTAGAAACCAGGGGAG
CTGGCACAGGTGGCCTGGGCTTGGCTGTTGAGGGTCCCTCAGAGGCCAAGATGTCTTGTATGGATAATAA
AGATGGCAGCTGCTCAGTAGAATACATCCCCTATGAAGCTGGAACCTATAGCCTTAATGTCACTTATGGT
GGTCACCAAGTGCCAGGTAGTCCCTTCAAGGTCCCTGTACATGATGTGACAGATGCATCTAAAGTCAAGT
GTTCTGGACCTGGCCTAAGCCCAGGCATGGTCCGTGCCAACCTCCCTCAGTCCTTTCAGGTGGACACAAG
CAAAGCTGGAGTTGCCCCACTGCAGGTCAAAGTGCAGGGGCCCAAAGGCCTGGTGGAGCCAGTGGATGTA
GTGGACAATGCTGATGGTACTCAGACTGTCAACTATGTGCCCAGCCGAGAAGGGTCCTATAGCATTTCTG
TGCTGTATGGTGAAGAAGAAGTGCCACGGAGCCCCTTCAAGGTCAAGGTGCTGCCTACACATGATGCCAG
TAAGGTGAAGGCCAGTGGACCTGGACTCAACACCACTGGTGTACCTGCTAGCCTGCCTGTGGAGTTCACC
ATTGATGCCAAGGATGCTGGGGAGGGTCTGTTGGCTGTCCAGATTACGGATCCTGAAGGCAAGCCCAAGA
AGACACACATTCAAGATAATCATGATGGCACATACACGGTGGCTTATGTGCCAGATGTGCCAGGCCGGTA
CACAATCCTCATCAAGTATGGTGGTGATGAGATTCCCTTTTCCCCGTACCGTGTCCGGGCTGTGCCCACT
GGGGATGCCAGCAAGTGCACAGTCACAGTGTCAATCGGAGGTCACGGGCTAGGTGCTGGCATTGGCCCCA
CCATCCAGATTGGGGAGGAGACGGTGATTACTGTGGACACAAAAGCAGCAGGCAAAGGCAAAGTGACTTG
TACTGTGTGCACACCTGATGGCTCAGAGGTAGACGTGGACGTGGTGGAGAATGAGGATGGCACCTTTGAC
ATCTTCTACACAGCTCCCCAACCGGGCAAATATGTCATCTGTGTGCGCTTCGGTGGCGAGCATGTGCCCA
ACAGCCCCTTCCAAGTTACAGCTTTGGCTGGGGACCAACCAACAGTGCAGACCCCATTAAGGTCTCAGCA
GCTGGCTCCACAGTATAACTATCCTCAGGGTAGCCAGCAAACCTGGATTCCAGAGAGGCCCATGGTGGGC
GTTAATGGGCTGGATGTGACCAGCCTGAGGCCCTTTGATCTTGTCATCCCCTTCACTATCAAGAAGGGGG
AGATCACTGGGGAAGTTCGAATGCCCTCAGGCAAGGTGGCCCAGCCTTCCATTACTGATAACAAAGATGG
CACTGTTACTGTACGTTACTCACCCAGTGAAGCTGGCCTGCATGAAATGGACATTCGCTATGACAATATG
CATATCCCAGGAAGCCCTCTGCAGTTCTATGTTGATTATGTCAACTGTGGCCACATCACTGCTTATGGTC
CTGGCCTTACCCATGGAGTGGTCAACAAACCTGCCACCTTCACTGTCAACACCAAGGATGCAGGAGAGGG
GGGCTTGTCTCTGGCCATTGAGGGTCCATCTAAAGCAGAAATCAGTTGCACTGACAACCAGGATGGAACA
TGCAGTGTCTCTTACCTGCCTGTACTGCCTGGTGACTATAGCATCCTAGTTAAGTACAATGATCAACACA
TCCCAGGCAGTCCCTTTACTGCCAGAGTAACAGGTGACGATTCCATGCGTATGTCCCACCTAAAGGTGGG
TTCTGCTGCTGATATCCCCATCAATATCTCAGAAACAGACCTTAGCCTACTCACAGCCACTGTGGTGCCA
CCTTCGGGTCGAGAGGAACCCTGTCTGCTGAAACGTTTGCGAAATGGCCACGTGGGGATTTCCTTCGTGC
CCAAGGAGACAGGGGAGCACCTGGTACATGTGAAGAAGAATGGCCAGCATGTGGCAAGCAGTCCCATCCC
AGTAGTGATCAGCCAGTCGGAGATAGGTGATGCCAGCCGTGTGAGGGTCTCTGGTCAAGGTCTTCATGAA
GGTCATACCTTTGAGCCTGCAGAGTTTATTATTGACACCAGAGATGCAGGCTACGGTGGGCTTAGTCTGT
CCATTGAGGGCCCTAGCAAAGTAGACATCAACACAGAGGATCTGGAGGATGGCACATGCAGGGTCACCTA
CTGTCCCACAGAGCCTGGAAACTACATTATAAACATCAAATTTGCTGACCAGCATGTGCCTGGCAGTCCC
TTTTCTGTGAAGGTGACAGGTGAGGGCCGGGTGAAAGAGAGTATCACACGCAGGCGACGTGCCCCTTCTG
TGGCCAATATTGGCAGTCATTGTGACCTCAGCCTGAAGATTCCTGAAATTAGCATCCAAGATATGACAGC
CCAGGTGACCAGCCCATCAGGCAAGACCCATGAGGCAGAGATCGTAGAAGGAGAGAACCATACTTACTGT
ATCCGATTTGTGCCTGCTGAGATGGGAATGCATACAGTCAGTGTCAAGTACAAGGGCCAGCATGTACCTG
GGAGCCCCTTCCAGTTCACTGTGGGGCCTCTGGGGGAAGGGGGTGCTCACAAGGTCCGTGCTGGAGGCCC
TGGCCTAGAGAGGGCTGAAGTTGGAGTGCCAGCGGAGTTCGGCATTTGGACTAGGGAAGCTGGCGCTGGA
GGCCTGGCCATTGCTGTTGAAGGCCCCAGCAAGGCTGAGATCTCTTTCGAGGACCGAAAGGATGGCTCCT
GTGGTGTGGCCTACGTAGTTCAGGAGCCAGGTGACTATGAGGTCTCAGTCAAGTTCAACGAGGAGCACAT
ACCTGATAGCCCCTTCGTGGTGCCTGTGGCTTCTCCGTCTGGTGACGCCCGCCGCCTTACTGTTTCTAGT
CTTCAGGAGTCAGGGTTAAAGGTCAACCAGCCAGCATCTTTTGCAGTCAGTCTGAATGGAGCCAAGGGGG
CAATTGATGCCAAGGTGCACAGCCCCTCAGGAGCTCTGGAGGAGTGCTATGTCACAGAGATTGACCAAGA
TAAGTATGCTGTGCGTTTCATCCCACGAGAGAATGGCATCTACTTGATTGATGTCAAGTTCAATGGTACT
CACATTCCTGGAAGTCCCTTCAAGATCCGAGTTGGGGAGCCTGGGCATGGAGGGGACCCAGGCTTAGTGT
CCGCCTATGGAGCAGGCCTGGAAGGTGGTGTCACAGGGAGCCCAGCAGAGTTTATTGTGAACACAAGCAA
TGCAGGAGCTGGTGCCCTTTCGGTTACCATTGATGGCCCCTCCAAGGTGAAGATGGATTGCCAGGAGTGC
CCCGAGGGCTATCGTGTCACCTATACCCCCATGGCACCTGGCAGCTACCTCATCTCCATCAAGTATGGTG
GCCCCTATCACATTGGTGGAAGTCCCTTTAAAGCCAAGGTCACAGGTCCTCGTCTTGTAAGCAACCACAG
CCTCCATGAGACATCATCTGTGTTTGTGGACTCTTTGACTAAAGTTGCCACGGTTCCCCAGCATGCAACC
TCAGGCCCAGGTCCTGCTGATGTCAGCAAGGTAGTAGCCAAAGGCCTGGGGCTAAGCAAGGCTTATGTAG
GCCAGAAGAGCAACTTCACAGTAGATTGCAGCAAAGCAGGTAACAACATGCTGCTGGTGGGCGTGCATGG
CCCAAGGACACCCTGTGAAGAGATCCTGGTGAAACACATGGGCAGCCGCCTCTATAGTGTCTCTTACCTG
CTCAAGGACAAAGGGGAGTACACACTGGTGGTCAAGTGGGGTGATGAGCATATCCCAGGCAGCCCATACC
GCATTATGGTACCCTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001290421
Insert Size 5967 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001290421.1, NP_001277350.1
RefSeq Size 8369 bp
RefSeq ORF 5967 bp
Locus ID 192176
Gene Summary Actin binding protein that promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins (By similarity). Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking. Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs (PubMed:17172441). Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (PubMed:20713593).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (2) contains multiple differences compared to variant 1, including initiation of translation at a downstream in-frame start codon. The encoded isoform (2) has a shorter N-terminus than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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