Ros1 (NM_011282) Mouse Untagged Clone

Specifications

Product Data
Type	Mouse Untagged Clone
Tag	Tag Free
Synonyms	c-ros; Ros-1
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >MC225283 representing NM_011282 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGAACATCTGCTGGCTCACCCTGAAACTTGTGAAGTTTGTGGTCCTTGGGTGCATCATATGGATTT CTGTGGCACAGAGTACAGTTCTGAGCAGCTGCCTAACGTCCTGTGTAACTAACCTGGGCAGGCAGCTTGA CAGTGGCACACGGTACAATCTGAGTGAGGCGTGCATCCATGGATGTCAGTTTTGGAACTCTGTAGATCAG GAAACGTGTGCTTTAAAGTGTAATGACACCTACGCCACCATTTGTGAGAGGGAGTCCTGTGAGGTCGGCT GCAGCAATGCGGAGGGTAGCTACGAAGAGGAAGTGCTGGAAAGCACAGAACTTCCTACAGCACCCTTTGC ATCTTCCATTGGAAGTCATGGTGTGACATTACGCTGGAACCCTGCCAACATCTCTGGAGTCAAATACATA ATTCAATGGAAATATGCCCAACTTCCAGGAAGCTGGACTTTCACGGAGACCGTGTCCAAGCTCTCATACA CGGTGGAACCCCTGCATCCATTCACAGAATATATTTTTCGAGTGGTTTGGATCTTCACAGCCCAACTGCA TCTTTATTCCCCACCAAGTCCCAGTTACAGGACTCATCCTTATGGAGTTCCAGAAACTGCACCTCTCATC CTGAACATGGAAAGCTGGAGCCCTGATACTGTGGAGGTCAGCTGGGCTCCACCTCATTTCCCAGGTGGAC CTATTTTGGGTTATAATTTAAGGCTCATCAGTAAAAATCAAAAATTAGATTCAGGGACACAGAGAACCAG TTTCCAGTTTTATTCTACTCTACCAAACACCACCTACAGGTTTTCTATCGCAGCAGTCAATGAAGTTGGT GAGGGGCCAGAAGCAGAATCTACAGTTACCACTCCATCCCCATCAGTTCAAGAAGAAGAACAATGGCTCT TTTTATCCAGAAAAACTTCTCTAAGAAAGAGGTCTTTGAAGTACTTAGTAGATGAAGCACATTGCCTTTG GTCAGATGCTATACACCATAATATTACAGGAATATCAGTCTATGCTCAGCAGCAAGTGGTTTATTTTTCA GAAGGAACTGTCATCTGGATGAAGGGGGCTGCCAACATGTCTGATGTGTCTGACCTGAGAATTTTTTACC AAGGCTCAGGTCTAGTGTCTTCTATCTCCATAGACTGGCTGTACCAAAGGATGTATTTCATCATGGATAA ACTGGTATATGTCTGTGAATTAAAGAATTGCTCAAATTTAGAGGAAATCACTCCCTTCTCTCTTATTGCA CCTCAGAAAGTTGTGGTTGACTCCTACAATGGGTACCTCTTTTATCTCCTGAGAGACGGCATCTACAGAG TCAATCTCCCTTTGCCATCTGGCAGGGACACCAAAGCTGTGCGTATTGTGGAGAGTGGCACATTAAAGGA CTTTGCAGTAAAGCCCCAATCCAAGCGAATCATTTACTTCAATGACACCATGCAACTCTTCATGTCAACG TTTCTGGATGGCTCTGCCTTCCACCGGGTCCTGCCTTGGGTCCCCCTTGTGACTGTGAAGAGCTTTGCTT GTGAAAACAATGACTTCCTCATCACAGATGGCAAGGCCATTTTTCAGCAGGACTCCCTGTCTTTCAATGA ATTCATCGTGGGATGTGACCTGAGTCACATAGAAGAGTTTGGGTTTGGTAACTTGGTCATCTTTGGCTCC TCTGTCCAGTCATACCCTCTGCCAGGACATCCACAGGAGGTCTCAGTGCTGTTTGGTTCTCGAGAGGCCC TTATTCAGTGGACGCCTCCTGCTCTCGCCATAGGAGCCAGTCCTTCCGCCTGGCAGAACTGGACTTATGA AGTCAAAGTTTATTCCCAGGACATCCTTGAAATCACTCAAGTTTTCTCGAACATAAGCGGGACCATGCTT AATGTACCCGAACTGCAGAGTTCTACAAAGTACACTGTCTCTGTGAGAGCAAGTTCTCCTAAAGGCCCAG GCCCCTGGTCAGCACCATCAGTGGGTACCACCTTGGTACCAGCTACTGAACCACCATTCATCATGGCTGT GAAAGAAGATGGGCTCTGGAGCAAACCACTCTGTAGTTTTGGTCCAGGAGAATTCCTGTCCTCTGATGTA GGAAACGTGTCAGATATGGATTGGTACAACAACAGCCTCTACTACAGTGACACAAAAGGCAACGTTTATG TGCGGCCTCTGAATGGGATGGATATCTCAGAGAATTATCACATACCCAGCATTGTAGGAGCTGGGGCTTT GGCCTTTGAATGGCTGGGTCACTTTCTCTACTGGGCTGGGAAGACATATGTGATCCAAAGGCAGTCTGTG TTGACGGGACACACGGACATTGTGACTCATGTGAAGCTGTTGGTGAATGACATGGCTGTGGATTCAGTTG GTGGCTATCTCTATTGGACAACACTCTACTCAGTTGAAAGCACCAGACTCAATGGAGAAAGTTCTCTTGT ACTACAGGCTCAGCCCTGGCTCTCTGGAAAAAAGGTTATTGCTCTAACACTAGACCTCAGTGATGGGCTC CTGTATTGGCTGGTGCAGGACAATCAGTGTATTCATCTGTACACAGCTGTTCTTCGAGGATGGAGTGGTG GGGATGCTACCATCACAGAGTTTGCAGCCTGGAGTACTTCTGAAATCTCCCAGAATGCACTGATGTACTA CAGTGGTAGACTCTTCTGGATCAATGGATTTAGGATCATTACAGCACAGGAAATAGGTCAGAGAACCAGT GTGTCTGTTTCGGAGCCAGCGAAATTCAATCAGTTCACAATTATACAGACATCTCTCAAGCCTCTGCCAG GAAACTTTTCCTCTACTCCCAAGGTTATCCCAGATCCTGTTCAGGAGTCTTCATTTCGAATTGAAGGACA CACTTCAAGTTTCCAAATCCTGTGGAATGAGCCCCCTGCGGTGGACTGGGGCATCGTTTTCTACAGTGTG GAATTTAGCACTCATTCCAAGTTCCTGATTATTGAACAACAGTCTTTACCTATTTTTACTGTGGAAGGAC TGGAGCCCTATACCTTATTTAATCTTTCTGTCACTCCTTATACCTACTGGGGAAAGGGCCAAAAAACATC TCTATCATTTCGTGCACCTGAATCAGTTCCATCAGCACCAGAAAACCCCAGAATATTTATATTGTCAAGC GGAAGATACACCAAGAAGAATGAAGTTGTGGTAGAGTTCAGGTGGAATAAACCTAAGCATGAAAATGGAG TGCTAACCAAATTTGAAATCTTCTATCACATATCTAAACAAAGTGGCACAAATAGATCAACTGAAGACTG GATGTCTGCCAGTGTTATACCCCCAGTGATGTCTTTTCAACTTGAGGCTGTGAGTCCTGAGTATACTGTT GCCTTCCAGGTTAGAGTCTTCACATCCAAAGGGCCAGGGCCATTTTCTGATATAGTGATGTCTAAAACAT CAGAAATCAAGCCATGTCCGTATCTCATATCTCTTCTCGGCAATAAGATCGTGTTTCTAGACATGGATCA AAATCAAGTTTTGTGGACATTTTCCCTGGAGGGAGACGTCAGCACAGTGGGGTACACAACAGACGATGAA ATGGGGTATTTCGCTCAAGGAGACACGCTCTTCCTTCTGAATTTGCGTAATCATTCCAGTTCCAAGCTTT TCCAGGATGCACTGGTTTCTGACATTAGAGTTATTGCTGTTGATTGGATTGCAAGGCACCTCTACTTTGC TCTGAAAGCATCACAAAACGGAACACAGATATTCAATGTTGACCTTGAACACAAGGTGAAATCCCCCAGG GAGGTGAAGACTTGCAAAGCACATACAACAATAATTTCTTTCTCTATATATCCCCTCTTGAGTCGCTTGT ATTGGACAGAAGTTTCAGATCTGGGCCATCAGATGTTCTACTGCAATATTAGCAATCACACCTCGCAACA TGTTCTACAACCCAAGGCTTCAAACCAACATGGAAGGAGTCAATGTTCTTGTAATGTGACAGAATCTGAG TTAAGTGGGGCAATGACTGTGGATACCTCTGACCCAGACAGACCATGGATATACTTTACCAAAAGGCAAG AGATCTGGGCCATGGATCTGGAAGGATGTCAGTGTTGGAAAGTCATCATGGTACCTACTATCCCTGGAAA AAGAATCATTAGCTTAACAGTGGATGGGGAGTTTATATATTGGATCATGAAAACAAAGGATGATGCCCAA ATTTATCAAGCAAAGAAGGGAAGCGGGGCCATCCTTTCCCAAGTGAAGGCCTCCAGGAGTAAGCATATCT TGGCTTACAGTTCTGCTCTGCAGCCTTTTCCAGATAAAGCATATCTGTCTCTAGCTTCAGATATGGTAGA AGCAACTATATTATATGCCACCAACACCAGCCTCACACTCAAATTACCTCCAGTCAAGACAAACCTCACG TGGCATGGTATTACCCACCCCACGTCAACATACCTGATTTACTATATGGAAGCTAATAGGGCAAACAGCT CTGACAGGAGACACAAAATGCTGGAATCACAGGAGAATGTAGCCCGGATTGAAGGTCTGCAGCCATTTTC AATGTACATGATTCAGATAGCTGTGAAGAACTATTATTCAGAGCCTTTAGAACATTTACCTCTTGGAAAA GAGATTCAAGGACAAACTAAAAGTGGAGTGCCTGGGGCAGTTTGTCATATCAACGCAACTGTGTTGTCGG ACACCAGTCTCCATGTATTCTGGACAGAATCCCATAAGCCAAACGGACCAAAAGAGTCAGTCCGCTATCA GCTGGTTATGTCATACCTGGCTCCCATTCCTGAGACTCCTCTAAGACAGGGTGAATTTCCAAGTGCCAAG CTTTCTCTGCTCATCACTAAACTATCTGGTGGACAGCTCTATGTGATGAAGGTTCTGGCGTGCCACCCTG AGGAAATGTGGTGTACTGAGAGTCATCCTGTCAGTGTCAACATGTTTGACACACCAGAGAAACCCTCTGC CTTGGTTCCAGAGAACACTAGTCTGCAGTTAGATTGGAAGGCTCGATCAAACGTTAACCTCACCGGATTT TGGTTTGAACTCCAGAAGTGGAAATATAATGAGTTTTACCATGTCAAAGCTTCATGCAGCCAAGGTCCAG TTTATGTCTGTAACATCACAGATCTACAACCTTACACCTCCTATAACATTCGAGTGGTGGTGGTCTATAC GACAGGAGAAAATAGCTCCTCCATTCCAGAGAGTTTCAAGACAAAAGCCGGAGTCCCAAGCAAACCAGGT ATTCCTAAATTACTAGAAGGGAGTAAAAATTCCATCCAGTGGGAAAAAGCTGAAGATAATGGGAGCAGAT TGATGTACTACACCCTTGAGGTCAGAAAAGGCATTTCAAATGACTCACAGAACCAGAGTTCAAGGTGGAA GGTGGTGTTTAATGGGTCCTGCAGTAGCATTTGCACATGGAGATCAAAAAACCTAAAAGGAACATTTCAG TTCAGAGCAGTTGCTGCAAATGAAATTGGACTTGGAGAATATAGTGAAATCAGTGAAGACATTACATTAG TGGAAGATGGTGTTTGGATAACAGAAACAAGTTTTATACTTACTATCATAGTTGGGATATTTCTGGTTGC TACAGTCCCACTGACCTTTGTCTGGCATAGAAGCTTGAAAAGTCACAAAGCTTCCAAGGAAGGCCTCTCG GTTCTCAACGACAACGACAAAGAGTTGGCTGAGCTTCGAGGTCTGGCGGCTGGAGTGGGACTGGCCAATG CCTGCTACGCAGTACATACTGTTCCAACCCAAGAAGAGATTGAAAATCTTCCTGCCTTCCCTCGGGAGAA GCTGAGCCTGCGTCTTTTGTTGGGAAGTGGAGCTTTTGGAGAAGTGTATGAAGGCACAGCTATAGACATC CTAGGCGTGGGAAGTGGAGAAATCAAAGTGGCAGTGAAGACCTTGAAGAAAGGTTCAACAGACCAGGAGA AGATTGAGTTCCTGAAGGAGGCGCACCTGATGAGCAAGTTTAATCACCCCAACATTCTGAAGCAGCTGGG AGTCTGTCTGTTAGGCGAACCCCAGTACATTATTCTGGAACTGATGGAAGGGGGAGACCTTCTAAGCTAT CTGCGCAAAGCTCGGGGGACAACGTTTCATGGTCCTTCACTCACCTTGCTTGACCTTGTAGAGCTGTGTG TAGATATTTCAAAAGGCTGCGTCTACTTGGAGCAGATGCACTTCATTCACAGGGATCTGGCAGCTCGGAA TTGCCTTGTATCAGTGAAAGACTACACCAGTCCTCGGGTAGTCAAGATTGGTGACTTTGGATTGGCAAGA GAAATCTATAAAAATGATTATTATAGAAAGAGAGGGGAAGGCCTGCTTCCTGTTCGGTGGATGGCTCCTG AAAACTTGATGGACGGAATCTTCACTTCTCAGTCTGATGTATGGTCCTTTGGAATTTTGGTGTGGGAGAT TTTAACTCTCGGTCATCAACCTTATCCAGCGCATTCCAACCTTGATGTTTTAAACTATGTGCAAGCAGGA GGGAGACTGGAGCCACCAAGAAATTGTCCTGATGATCTGTGGAATTTAATGTCCCAATGCTGGGCTCAAG AACCTGACCAAAGACCCACTTTCCATAACATTCAAAACCAGCTTCAGTTATTCAGAAATGTTTTCTTAAA CAATGTTTCTCATTGTGGAGAAGCAGCTCCCACCGGTGGAGTCATCAACAAAGGCTTTGAAGGTGAAGAT GATGAAATGGTCACTTTGAACTCAGATGACACGATGCCAGTTGCCTTGATGGAAACCAAGAACCAAGAAG GATTAAATTATATGGTGCTTGCCACAAAATGTAGCCAAGGTGAAGGAAGTTATGAGGGTCCTCTAGGCCC TAAGGAACTTGGGTCATGTGATCTGAAGAAAGACAAGAAGCAACCACAGGCAGACAAAGATTTCTGCCAG GAACCACAGGTGGCTTATGGCTCTCCTGGCCTGTCTGAAGGCCTGAATTATGCCTGTCTTGCTCACAGTG AACATGGAGATGTGTCTGAATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_011282
Insert Size	7023 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_011282.2, NP_035412.2
RefSeq Size	7401 bp
RefSeq ORF	7023 bp
Locus ID	19886
UniProt ID	Q78DX7
Gene Summary	Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1, and PLCG2.[UniProtKB/Swiss-Prot Function]

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