Hc (NM_010406) Mouse Untagged Clone
CAT#: MC224814
Hc (untagged) - Mouse hemolytic complement (Hc), (10ug)
CNY 26,980.00
货期*
8周
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (3)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | C5; C5a; He |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC224814 representing NM_010406
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCGCTACCAGCCATGGGTCTTTGGGGAATACTTTGTCTTTTAATTTTCCTGGACAAAACTTGGGGAC AGGAACAAACCTACGTCATTTCAGCACCCAAAATCCTCCGGGTCGGCTCGTCTGAAAATGTGGTAATTCA AGTCCATGGCTACACTGAAGCATTTGATGCAACTCTTTCTCTAAAAAGCTATCCTGACAAAAAAGTCACC TTCTCTTCAGGCTATGTTAATTTGTCCCCGGAAAACAAATTCCAAAACGCGGCACTGTTGACACTACAGC CCAATCAAGTTCCTAGAGAAGAAAGCCCAGTCTCTCACGTGTATCTGGAAGTTGTGTCAAAACACTTTTC AAAATCAAAGAAAATACCAATTACCTATAACAATGGAATTCTCTTCATCCATACAGACAAACCTGTTTAC ACGCCGGACCAGTCAGTAAAGATCAGAGTCTATTCTCTGGGTGACGACTTGAAGCCAGCCAAACGGGAGA CTGTCTTAACTTTCATAGACCCCGAAGGATCAGAAGTTGACATTGTAGAAGAAAATGATTACACCGGAAT TATCTCTTTTCCTGACTTCAAGATTCCATCTAATCCCAAGTATGGTGTTTGGACAATTAAAGCTAACTAT AAGAAGGATTTTACAACAACTGGAACTGCATACTTTGAAATTAAAGAATATGTCTTGCCACGATTCTCTG TTTCAATAGAACTAGAAAGAACCTTCATTGGCTATAAAAACTTTAAGAACTTTGAAATCACTGTGAAAGC AAGATATTTTTATAATAAAGTGGTACCTGATGCTGAAGTGTATGCCTTTTTTGGATTGAGAGAGGACATA AAAGATGAGGAGAAGCAGATGATGCACAAAGCCACACAAGCCGCAAAGTTGGTTGACGGAGTTGCTCAGA TCTCTTTTGATTCTGAAACAGCAGTTAAAGAGCTGTCCTACAACAGTCTAGAAGACTTAAACAACAAGTA CCTTTATATTGCAGTAACAGTCACAGAATCTTCAGGTGGATTTTCAGAAGAGGCAGAAATCCCTGGAGTC AAATATGTCCTCTCTCCCTACACACTGAATTTGGTCGCTACTCCTCTTTTCGTGAAGCCCGGGATTCCAT TTTCCATCAAGGCACAGGTTAAAGATTCACTCGAGCAGGCGGTAGGAGGGGTCCCAGTAACTCTGATGGC ACAAACAGTCGATGTGAATCAAGAGACATCTGACTTGGAAACAAAGAGGAGCATCACTCATGACACTGAT GGAGTAGCTGTGTTTGTGCTGAACCTCCCATCAAATGTGACGGTGCTAAAGTTTGAGATCAGAACTGATG ACCCAGAACTTCCCGAAGAAAATCAAGCCAGCAAAGAGTACGAAGCAGTTGCGTACTCGTCTCTCAGCCA AAGTTACATTTACATCGCTTGGACTGAAAACTACAAGCCCATGCTTGTGGGAGAATACCTGAATATTATG GTTACCCCCAAGAGCCCATATATCGACAAAATAACTCACTATAATTACTTGATTTTATCCAAAGGCAAAA TTGTACAGTACGGCACAAGAGAGAAACTTTTCTCCTCAACTTATCAAAATATAAATATTCCAGTGACACA GAACATGGTTCCTTCAGCACGACTCCTGGTCTATTACATAGTCACAGGGGAGCAAACAGCAGAATTAGTG GCTGACGCAGTCTGGATAAATATTGAGGAGAAGTGTGGCAACCAGCTCCAGGTCCATCTGTCTCCAGATG AATATGTGTATTCTCCAGGCCAAACTGTGTCCCTTGACATGGTGACTGAAGCAGACTCATGGGTAGCACT ATCAGCAGTGGACAGAGCTGTGTATAAAGTCCAGGGAAACGCCAAAAGGGCCATGCAAAGAGTCTTTCAA GCTTTGGATGAAAAGAGTGACCTGGGCTGTGGGGCAGGTGGTGGCCATGACAATGCAGATGTATTCCATC TAGCTGGGCTCACCTTCCTCACCAACGCAAACGCAGATGACTCCCATTATCGTGATGACTCTTGTAAAGA AATTCTCAGGTCAAAGAGAAACCTGCATCTCCTAAGGCAGAAAATAGAAGAACAAGCTGCTAAGTACAAA CATAGTGTGCCAAAGAAATGCTGCTATGACGGAGCCCGAGTGAACTTCTACGAAACCTGTGAGGAGCGAG TGGCCCGGGTTACCATAGGCCCTCTCTGCATCAGGGCCTTCAACGAGTGCTGTACTATTGCGAACAAGAT CCGAAAAGAAAGCCCCCATAAACCTGTCCAACTGGGAAGGATCCACATTAAGACCCTGTTACCAGTGATG AAGGCAGATATCCGAAGCTACTTTCCAGAGAGCTGGCTATGGGAAATTCATCGCGTTCCCAAAAGAAAAC AGCTGCAGGTCACGCTGCCTGACTCACTAACGACTTGGGAAATTCAAGGCATTGGCATTTCAGACAATGG TATATGTGTTGCTGATACACTCAAGGCAAAGGTGTTCAAAGAAGTCTTCCTGGAGATGAACATACCATAT TCTGTTGTGCGAGGAGAACAGATCCAATTGAAAGGAACTGTTTACAACTATATGACCTCAGGGACAAAGT TCTGTGTTAAAATGTCTGCTGTGGAGGGGATCTGCACTTCAGGAAGCTCAGCTGCTAGCCTTCACACCTC CAGGCCCTCCAGATGTGTGTTCCAGAGGATAGAGGGCTCGTCCAGTCACTTGGTGACCTTCACCCTGCTT CCTCTGGAAATTGGCCTTCACTCCATAAACTTCTCACTAGAGACCTCATTTGGGAAAGACATCTTAGTAA AGACATTACGGGTAGTGCCAGAAGGAGTCAAGAGGGAAAGCTATGCCGGCGTGATTCTGGACCCTAAGGG AATTCGTGGTATTGTTAACAGACGAAAGGAATTCCCATACAGGATCCCATTAGATTTGGTCCCCAAGACC AAAGTTGAAAGGATTTTGAGTGTCAAAGGACTGCTTGTAGGGGAGTTCTTGTCCACGGTTCTGAGTAAGG AAGGCATCAACATCCTAACCCACCTCCCCAAGGGCAGTGCAGAGGCAGAGCTCATGAGCATAGCTCCGGT GTTCTATGTTTTCCACTACCTGGAAGCAGGAAACCATTGGAATATTTTCTATCCTGATACACTGAGTAAA AGACAGAGCCTGGAGAAAAAAATAAAACAAGGGGTGGTGAGCGTCATGTCCTACAGAAACGCTGACTATT CCTACAGCATGTGGAAGGGGGCGAGCGCTAGTACCTGGCTGACAGCTTTTGCTCTGAGAGTGCTTGGACA GGTGGCCAAGTATGTAAAACAGGATGAAAACTCAATTTGTAACTCTTTGCTATGGCTGGTTGAGAAGTGT CAGCTGGAAAACGGCTCTTTCAAGGAAAATTCCCAATATCTACCAATAAAATTACAGGGTACTTTGCCTG CTGAAGCCCAAGAGAAAACTTTGTATCTTACAGCCTTTTCTGTGATTGGAATTAGAAAGGCAGTTGACAT ATGCCCCACCATGAAAATCCACACAGCGCTAGATAAAGCCGACTCCTTCCTGCTTGAAAACACCCTGCCA TCCAAGAGCACCTTCACACTGGCCATTGTAGCCTATGCTCTTTCCCTAGGAGACAGAACCCACCCGAGGT TTCGTCTAATTGTGTCGGCCCTGAGGAAGGAAGCTTTTGTTAAAGGTGATCCGCCCATTTACCGTTACTG GAGAGATACCCTCAAACGTCCAGACAGCTCTGTGCCCAGCAGCGGCACAGCAGGTATGGTTGAAACCACA GCCTATGCTTTGCTCGCCAGCCTGAAACTGAAGGATATGAATTACGCCAACCCCATCATCAAGTGGCTAT CTGAAGAGCAGAGGTATGGAGGCGGCTTTTATTCCACCCAGGATACGATTAATGCCATCGAGGGCCTGAC AGAATATTCACTCCTGTTAAAACAAATTCATTTGGATATGGACATCAATGTCGCCTACAAACACGAAGGT GACTTCCACAAGTATAAGGTGACAGAGAAGCATTTCCTGGGGAGGCCAGTGGAGGTATCTCTCAATGATG ACCTTGTTGTCAGCACAGGCTACAGCAGTGGCTTGGCCACAGTATATGTAAAAACTGTGGTTCACAAAAT TAGTGTCTCTGAGGAATTTTGCAGCTTTTACTTGAAAATTGATACCCAAGATATTGAAGCATCCAGCCAC TTCAGGCTCAGTGACTCTGGATTCAAGCGCATAATAGCATGTGCCAGCTACAAGCCCAGCAAGGAGGAGT CAACATCCGGGTCCTCCCATGCAGTAATGGATATATCACTGCCGACTGGAATCGGAGCAAACGAGGAAGA TTTACGGGCTCTTGTGGAAGGAGTGGATCAACTACTAACTGATTACCAGATCAAAGATGGCCATGTCATT CTGCAACTGAATTCGATCCCCTCCAGAGATTTCCTCTGTGTCCGGTTCCGGATATTTGAACTTTTCCAAG TTGGGTTTCTGAATCCTGCTACCTTCACGGTGTACGAGTATCACAGACCAGATAAGCAGTGCACCATGAT TTATAGCATTTCTGACACCAGGCTTCAGAAAGTCTGTGAAGGAGCAGCTTGCACATGTGTGGAAGCTGAC TGTGCGCAACTGCAGGCAGAAGTAGACCTAGCCATCTCTGCAGACTCCAGAAAAGAGAAAGCCTGTAAAC CAGAGACTGCATATGCTTATAAAGTCAGGATCACATCAGCCACTGAAGAAAATGTTTTTGTCAAGTACAC TGCGACTCTTCTGGTCACTTACAAAACAGGGGAAGCTGCTGATGAGAATTCGGAGGTCACCTTCATTAAA AAGATGAGCTGTACCAATGCCAACCTGGTGAAAGGGAAGCAGTATTTAATCATGGGCAAAGAGGTTCTGC AGATCAAACACAATTTCAGTTTCAAGTATATATACCCTCTAGATTCCTCCACCTGGATTGAATATTGGCC CACAGACACAACGTGTCCATCCTGTCAAGCATTTGTAGAGAATTTGAATAACTTTGCTGAAGACCTCTTT TTAAACAGCTGTGAATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_010406 |
Insert Size | 5058 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_010406.2, NP_034536.2 |
RefSeq Size | 5448 bp |
RefSeq ORF | 5058 bp |
Locus ID | 15139 |
UniProt ID | P06684 |
Gene Summary | This gene encodes a component of the complement system, a part of the innate immune system that plays an important role in inflammation, host homeostasis, and host defense against pathogens. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the C5 alpha chain, C5 beta chain, C5a anaphylatoxin and C5b. The C5 protein is comprised of the alpha and beta chains, which are linked by a disulfide bridge. Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin, which possesses potent spasmogenic and chemotactic activity, and the C5b macromolecular cleavage product, a subunit of the membrane attack complex (MAC). Mice with a homozygous mutation in this gene exhibit impaired bone fracture healing and an enhanced inflammatory response in an allergic lung disease model. [provided by RefSeq, Nov 2015] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Customer
Reviews
Loading...