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Stk36 (NM_175031) Mouse Untagged Clone
CAT＃: MC224228
Stk36 (untagged) - Mouse serine/threonine kinase 36 (fused homolog, Drosophila) (Stk36), (10ug)
CNY 16,910.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1700112N14Rik; B930045J24; FU; Fused; mKIAA1278 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224228 representing NM_175031
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAAAAGTACCACGTTTTGGAGATGATTGGAGAAGGCTCTTTTGGGAGAGTGTATAAGGGCCGAAAAA AATACAGTGCTCAGGTGGTGGCCTTGAAGTTCATCCCCAAACTGGGGCGCTCAGAGAAAGAGCTGAGGAA TCTGCAACGAGAGATTGAAATCATGCGGGGTCTGTGGCATCCCAACATTGTGCATATGCTCGACAGCTTT GAGACTGACAAAGAGGTGGTGGTGGTGACAGACTACGCTGAAGGAGAACTCTTTCAGATTCTGGAAGATG ATGGAAAACTTCCTGAAGACCAGGTTCAGGCCATCGCTGCCCAGTTGGTGTCAGCTCTGTACTACCTGCA TTCCCACCGCATCCTACACCGCGACATGAAACCGCAGAACATTCTTCTCGCCAAGGGTGGTGGCATTAAA CTTTGTGACTTTGGATTCGCCCGAGCTATGAGCACCAACACCATGGTGCTGACGTCGATCAAAGGCACAC CGCTCTATATGTCTCCAGAGCTGGTGGAGGAGCGACCATATGACCACACCGCAGACCTCTGGTCTGTGGG CTGCATCCTGTATGAGCTGGCTGTCGGCACGCCTCCCTTCTACACCACCAGCATCTTTCAGCTGGTTAGC CTCATTCTCAAGGACCCTGTGCGCTGGCCCTCCACCATTAGTTCCTGCTTCAAGAACTTCTTGCAGGGGC TGCTCACCAAGGACCCCCGGCAGCGTCTGTCCTGGCCAGACCTCTTACATCACCCCTTTATTGCCGGCCG TGTCACCATCATAACTGAACCAGCAGGCTCCGATTTGGGCACCCCATTTACTAGTCGCCTACCCCCAGAA CTTCAGGTCCTCAAGGATGAACAGGCGCATCGGCTCGCACCCAAGGGTAACCAGTCTCGCATCCTGCGCC AGGCCTGTAAACTCATGGCTGAAGAAGCCAAGCAGAAGGAAGACCAAAATGCAGGATCTGCCCTTGAACA AGAAGACGGGCTCTGCAAGGTGACACCCAGCACAGCCCCCGTGCCTGGACTAAAGGCCACTCCTCAGGAG TCAAGCCTCTTGGCTGGTATACTGGCTTCAGAAATGAAGAACAACTGGGAAGACTGGGGGGCTGGAGAAG CACCCCGTACCTCTCGGGAAAACCACATCAACCTGGAGTGTGAACAAGGCTTCCCAGAGCCGAGGCCAGA GGCGATGGGCCGGCAGAGCACTGATGTAGTGGATCCTGAAAATGAGGAGCCAGACAGTGATGATGAGTGG CAACGCCTACTAGAGACCAGCGAGCCTGGGCCTGTGCAGCTGAAGTCCCCCCTCACCCTGTTGTGTAACC CTGACTTCTGCCAGCGCATCCAGAGTCAGCTGCGCGGGACTGGCGAGCAGATCCTGAAAGGCGTTCTGGA TGGTGTGTCCCACCTCCTTCCTGTACTCCGCATCCTGAGTAGTCTCCTATCCAGCTGCAATGACTCTGTG CTCTTGTATTCCTTCTGCCAGGAGGCAGGACTGCCTGAGCTGCCTCTCAGCCTTCTTAGGTACAGCCAGG AGAGTAGCAGCATCCAGCAGCAACCTTGGTATGGGGCGCTCTTACGGGACCTGGTGGCTGTGGTTCAGGC CTACTTTTCGTGCACCTTCAATCTGGAGAGGAGCCAGACAGGTGACAGCCTACAGGTGTTTCAGGAGGCC GCCAGCCTCTTTTTGGACCTGTTGGGGAAGCTGCTGGCCCAATCAGATGATTCCGAGCAGACATTTCGAA GGGATAGCCTTATGTGCTTTGCTGTCTTGTGTGAAGCTGTGGACGGAAACAGCTGGGCCGTCTCCAAAGC CTTCTACTCCAGCCTGTTGACCACACAGCGCGCTGTGTTGGATGGCCTCCTTCACGGCCTGACAGTCCCA CAGCTTCCTTTCCACACACCACCAGGAGCCCCACAAGTGAGCCAGCCGCTGCGGGAGCAGAGTGAAGATG TACCTGGAGCCATCTCTTCTGCCCTGGCAGCCATGTGTACTGCTCCTGTGGGGCTGCCCAGCTGTTGGGA TGCCAAGGAGCAGGTCTCTTGGCATTTGGCCAACCAGCTAACTGAAGACAGCAGCCAACTGAGGCCATCC CTCATCTCTGGTCTGCGACACCATGTCCTGTGCCTCCACCTTCTCAAGGTTCTCTACGCCTGCTGCTATA TTAGTGAGCGCCTGTGCCATATTCTGGGGCAAGAGCCCCTGGCCTTGGAGTCGCTGCTGATGTTAGTCCA GGGCAAGGTGAAAGTAGCAGATTGGGAAGAGTCCACTGAGGTGGCACTTTACCTCCTGTCCCTTCTTGTC TTTCGGCTCCAAGATCTGCCTTCAGGGATGGAGAAGCTGGGCAGTGAGGTTGCTACTCTCTTTACCCACT CACATGTCGTCTCTCTTGTGAATGCGGCAGCCTGTCTCTTAGGACAGCTTGGTCAGCAAGGGGTGACCTT TGACCTCCAGCCCCGGGAATGGATTGCTGCAGCTGCACATGCCTTGTCTGCCCCTGCAGAGGTCCGGCTG ACTCCGCCGTATAGTTGTGGCTTCTATGATGGCCTCCTCATTCTCCTGCTTCAGCTTCTTATGCAGGTAC AGGGGAAGCCTGGCCTGATCAGGGATGTGGTTGGTTCAGAGGTGTGGACCATTCTGTGGCACCGCTTTTC CATGGCCCTGAGGCTGCCCGAGGAGGTGTCTGCCCAGGAAGACGACCTGCTACTATCAAGTCCCTCCAGC CTAGAGCCAGACTGGACACTGATTTCACCCCAAGGCATGGCAGCCTTGCTGAGCCTGGCCATGGCCATCT TCACCCAGGAGTCCCAGTTATGCCTGAGCCACCTGTCCCAGCATGGCAGTGTCCTCATGCTGACCCTGAA GCACCTGCTTTCACCCAGCTTCTTGCACCACCTGAGCCAGGCGCCGCAGGGGCCCGAGTTTCTCCCCGTT GTGGTGCTCTCCGTGTGCAAGCTGCTCTGCTTCCCTTTTGCCCTGGATGTGGATGCTGACCTCCTTGTAG GTGTCTTGGCTGACCTCAGGGCCTCGGAAGTGGTAGTCTGCCTGCTGCAGGTCTGCTGCCACCACCTTTC GTTGTTACAAGCAGAGCTGCCCATTGGCCTCCTTACACGCCTGGCCCTCACGGATTCTGCCTCTCTCAAG CAGTTTGTGAACACAGTGGCCACCTCTTCTAGAGCCATCATCTCATTCCTCTCTGTTGTTCTCCTGAGTG ACCAGCCCCTCATGATCTCTGACCTCCTGTCCCTGCTGACACACACAGCCCGGATTCTGTCCCCCAGCCA CTTGTCCTTTATCCAAGAGCTCCTGTCTGGCTCTGATGAATCCTATCGGCCATTGCGCAGCCTCCTAGGC CACTCAGAGAACACTGTGCGGGTCCGTGCATATGGGCTCCTGGGACATTTATTACAGCACAGCATGGCCC TACGTGGGGCACTACAGAGTCAGTCAGGACTGCTCAACCTTCTGCTGCTAGGGCTTGGAGACAAGGACCC TGCCGTGCGACGCAGTGCCAGCTTTGCTGTGGGCAATGCAGCCTACCAGGCTGGGCCTTTGGGACCTGCC TTGGCAGCTGCAGTGCCCAGTATGACCCAGCTGCTTGGAGATGCTCAGGATGGGATCCGGCGCAATGCTG CATCAGCTCTAGGCAATCTGGGACCTGAAGGATTGGGCAAGGAGCTATTAAAGTGCCAAGTACCCCAGCG GCTCCTAGAAATGGCATGTGGAGACCCTCAGCCAACTGTCAAAGAGGCTGCCCTCATTGCCCTTCGAAGC CTCCAACAGGAGTCCTGTATTCATCAGGTGCTGGTGTCGCTGGGTGCCAGTGAGAAGTTAGCCTTGCTCT CTTTGGGGAATCAGTTACTGCCGAATAGCAGCAACAGGCCTGCCTCCGTCAGACACTGCAGGAAGCTCAT CCAACTCCTGAGGCCAACCCACAGCACATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_175031 |
| Insert Size | 3951 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_175031.3, NP_778196.2 |
| RefSeq Size | 5329 bp |
| RefSeq ORF | 3951 bp |
| Locus ID | 269209 |
| UniProt ID | Q69ZM6 |
| Gene Summary | Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Essential for construction of the central pair apparatus of motile cilia.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG218007 | Stk36 (tGFP-tagged) - Mouse serine/threonine kinase 36 (fused homolog Drosophila) (Stk36), (10ug) |
CNY 12,730.00 |
|
| MR218007 | Stk36 (Myc-DDK-tagged) - Mouse serine/threonine kinase 36 (fused homolog, Drosophila) (Stk36) |
CNY 9,160.00 |
|
| MR218007L3 | Lenti ORF clone of Stk36 (Myc-DDK-tagged) - Mouse serine/threonine kinase 36 (fused homolog, Drosophila) (Stk36) |
CNY 13,490.00 |
|
| MR218007L4 | Lenti ORF clone of Stk36 (mGFP-tagged) - Mouse serine/threonine kinase 36 (fused homolog, Drosophila) (Stk36) |
CNY 13,490.00 |
