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Srcin1 (NM_018873) Mouse Untagged Clone
CAT＃: MC223972
Srcin1 (untagged) - Mouse SRC kinase signaling inhibitor 1 (Srcin1), (10ug)
CNY 15,580.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | mKIAA1684; P140; p140Cap; SNIP |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223972 representing NM_018873
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGAACGCTCCGTCCCAAGATCCGGAGCGGAGCAGCCCCCCCATGCTGTCTGCAGACGATGCCGAGT ACCCTCGGGAGTACCGGACCCTGGGGGGTGGGGGCGGAGGTGGCAGCGGGGGCCGGCGCTTCTCCAACGT GGGGCTGGTGCACACCTCGGAGCGCCGGCACACGGTGATCGCTGCCCAGAGCCTGGAGGCCCTCAGCGGG CTCCAGAAAGCGGATGCTGACCGCAAGCGAGATGCGTTCATGGACCACCTGAAGAGCAAGTACCCTCAGC ACGCCCTGGCCCTGCGAGGTCAGCAGGACAGGATGCGAGAACAGGTCGGCGGCTGGACCGTGGACCCTGT GTGCCTCCTCAGCTCCCTCTGTTCCCACCTCCACGGCGACTCCACCCCCTCAGGGGCTGGCCAGCCTGCC CAGCAACCAAACTACTGGAGTTTCAAGACCCGCAGCTCGCGCCATACTCAGGGAGCCCAGCCAGGGCTAG CAGACCAGGCAGCCAAGCTGTCCTACGCCTCGGCTGAGTCGCTGGAGACAATGTCCGAGGCCGAGCTGCC CCTGGGCTTCAGCAGGATGAACCGCTTCCGACAGAGCTTGCCTCTCTCCCGCTCTGCCAGCCAGACCAAG CTGCGCTCACCAGGGGTCCTGTTCCTGCAGTTTGGAGAGGAGACACGACGTGTACACATCACGCATGAGG TCAGCAGCTTGGACACGCTGCACGCACTCATCGCGCACATGTTCCCTCAGAAGCTCACCATGGGCATGCT TAAGTCGCCCAACACCGCCATCCTCATCAAGGACGAGGCTCGCAATGTCTTCTACGAGCTGGAAGACGTC CGGGATATCCAAGACCGAAGTATCATTAAGATCTATAGGAAGGAGCCGTTGTATGCTGCTTTTCCTGGCT CACACCTCACCAACGGTGACCTCCGGAGAGAAATGGTTTACGCGTCGCGGGAGTCGTCGCCCACGCGGCG CCTCAACAACCTGTCGCCCGCATCGCACCTAGCATCTAGCTCCCCGCCTCCAGGGCTGCCATCGGGGCTG CCTTCGGGACTGCCATCGGGCTCGCCTTCGCGTTCACGCCTCTCCTATGCTGGGGGCCGGCCGCCCTCTT ACGCCGGCAGCCCGGTGCACCACGCGGCTGAGCGACTGGGAGGCGCCCCGACCGGCCAGGGCGTGAGCCC CAGCCCCAGCGCCATCCTGGAGCGGCGCGACGTGAAGCCAGATGAGGACCTGGCGGGCAAGGCTGGCGGC ATGGTGCTGGTGAAGGGCGAGGGCCTCTATGCCGATCCCTACGGGCTGCTGCACGAGGGCCGTCTGAGCC TGGCCGCCGCGGCGGGAGACCCATTCGCATACCCGGGCGCGGGCGGCTTGTACAAGCGGGGTTCCGTGCG CTCTCTCAGCACCTACTCCGCTGCCGCGCTGCAGTCCGACCTGGAGGACTCGCTGTACAAGGCGGGCGCT GGCGGCCCGCTCTACGGAGACGGCTATGGCTTCCGTCTGCCGCCCTCGTCCCCGCAGAAGCTGGCCGACG TCTCGGCGCCCTCCGGGGGACCTCCACCCCCGCACAGCCCCTACTCCGGGCCACCCAGCCGCGGCTCGCC GGTGCGCCAGTCCTTCCGCAAAGATTCGGGCTCCTCGTCGGTCTTTGCTGAGAGTCCTGGAGGCAAGGCC CGCAGCACCGGGAGTGCCTCCACGGCCGGAGCACCACCTTCTGAACTCTTCCCTGGACCTGGGGAGCGCT CCCTTGTAGGGTTCGGGCCGCCGGTGCCAGCCAAAGACACAGAGACCAGGGAACGCATGGAGGCTATGGA GAAGCAGATTGCCAGCCTCACTGGCCTAGTACAGAGTGCCCTACTGCGAGGCTCAGAGCCGGAGACCCCA AGTGAGAAGGTTGAAGGCTCCAATGGAGCAGCCACTCCCTCAGCACCAGTGTGTGGGTCAGGCAGTAAGA GTAGCGGGGCCACTCCGGTGTCGGGCCCTCCCCCGCCCTCGGCCAGCAGCACCCCTGCAGGGCAGCCCAC TGCTGTCAGCCGTCTGCAGATGCAGCTGCATCTGCGTGGCCTACAGAACAGCGCTAGCGACCTGCGTGGC CAGCTTCAGCAGCTGCGCAAGCTCCAGCTCCAGAACCAGGAGTCGGTGCGCGCGCTGCTGAAGCGCACCG AGGCGGAGCTGAGCATGCGCGTGTCGGAGGCGGCGCGGCGGCAGGAGGACCCGCTGCAGCGGCAGCGCAC CCTGGTGGAGGAGGAGCGTTTGCGTTACCTCAACGACGAGGAGCTCATTACTCAGCAGCTCAATGACCTC GAGAAGTCAGTGGAGAAGATCCAGAGAGACGTGGCCCATAACCACCGGCTAGTGCCGGGTCCTGAGTTGG AAGAGAAGGCGCTGGTGCTGAAGCAGCTTGGGGAGACGCTGACGGAGCTCAAGGCTCATTTCCCAGGCCT GCAGAGTAAGATGCGGGTGGTGCTGCGCGTGGAGGTGGAGGCAGTGAAGTTCCTGAAGGAGGAACCTCAA CGCCTTGACGGGCTCCTCAAGCGCTGCCGGGGGGTCACTGACACGCTGGCCCAGATCCGAAGGCAAGTGG ATGAGGGTATGTGGCCCCCCCCCAACAACCTCCTGAACCAGTCCCCCAAGAAGGTGGCAGCTGAAACCGA CTTCAGCAAAGGCTTGGATTTTGAAATACCACCCCCGAGTCCTCCACTGAATCTTCACGAGCTGAGTGGA CCTGCCGAAGGCACCCCTCTCACCCCAAAGAGCACTAACCCCACCAAAGGCCTGGATGCTTCCAGCAAGA GAAACACGGACAAAGCTGTGTCTGTTGAGGCTGCGGAGAGAGACTGGGAAGAGAAGCGGGCAGCCCTGAC CCAGTACAGCGCCAAGGACATCAACCGGCTGCTGGAAGAGACCCAGGCTGAGCTGCTCAAGGCTATCCCT GACCTGGACTGTGCCAGCAAGACCCACCCAGGCCCTGCTCCCACTCCAGACCACAAGCCCCCTAAGGCAC CCCATGGTCAGAAGGCAGCTCCCCGGACAGAGCCCAGTGGGAGAAGAGGATCAGATGAGCTCACAGTGCC CCGATACCGCACAGAGAAGCCCTCCAAGTCACCCCCGCCACCCCCTCCCCGCCGGAGCTTCCCTTCCTCC CATGGCCTGACCACAACACGCACTGGAGAAGTGGTGGTCACCAGTAAGAAAGACTCAGTCTTCATCAAGA AGGCTGAGTCCGAGGAGCTAGAGGTCCAGAAGCCCCAGGTGAAGCTGCGCCGTGCTGTGTCTGAGGTGGT CCGCCCCGCATCCACGCCGCCCATTATGGCCTCTGCCATCAAGGACGAGGACGACGAGGAGAGGATCATT GCTGAGCTGGAGAGTGGTGGTAGCAGCGTGCCACCCATGAAGGTGGTGACTCCCGGAGCCTCGAGGCTGA AGGCGGCCCAGGGCCCAGCAGGCAGCCCTGATAAAGGCAAACATGGCAAGCAACGAACGGAATACATGAG GATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGGTGAGCGGTCCGAATGAGACCTCAAGCCCC GGCTCAGAAAAGCCCTCTGGTTCCAGAACCTCCATCCCTGTATTGACTTCCTTTGGGGCAAGGAATTCTT CCATCTCCTTCTAG ACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGA TTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-NotI |
| ACCN | NM_018873 |
| Insert Size | 3654 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018873.2, NP_061361.2 |
| RefSeq Size | 6965 bp |
| RefSeq ORF | 3654 bp |
| Locus ID | 56013 |
| UniProt ID | Q9QWI6 |
| Gene Summary | Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222798 | Srcin1 (tGFP-tagged) - Mouse SRC kinase signaling inhibitor 1 (Srcin1), (10ug) |
CNY 13,400.00 |
|
| MR222798 | Srcin1 (Myc-DDK-tagged) - Mouse SRC kinase signaling inhibitor 1 (Srcin1) |
CNY 12,720.00 |
|
| MR222798L3 | Lenti ORF clone of Srcin1 (Myc-DDK-tagged) - Mouse SRC kinase signaling inhibitor 1 (Srcin1) |
CNY 14,060.00 |
|
| MR222798L4 | Lenti ORF clone of Srcin1 (mGFP-tagged) - Mouse SRC kinase signaling inhibitor 1 (Srcin1) |
CNY 14,060.00 |
