United States
Germany
Japan
United Kingdom
China
Nrcam (NM_001146031) Mouse Untagged Clone
CAT＃: MC223870
Nrcam (untagged) - Mouse neuron-glia-CAM-related cell adhesion molecule (Nrcam), transcript variant 2, (10ug)
CN¥ 15,200.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Bravo; C030017F07Rik; C130076O07Rik; mKIAA0343 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223870 representing NM_001146031
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCAGCTTAAAATAATGCCGAAGAAGAAGCACTTATCTGCAGGCGGAGTGCCCCTGATTCTCTTCCTGT GCCAGATGATCAGCGCGCTGGATGTTCCTCTCGATCTGGTACAACCTCCAACCATCACTCAACAGTCACC AAAAGACTACATCATTGACCCTCGGGAGAATATTGTAATCCAGTGTGAGGCCAAAGGGAAACCTCCCCCA AGCTTTTCCTGGACTCGTAATGGAACTCACTTTGACATAGACAAGGACCCTCTGGTCACCATGAAGCCTG GCTCAGGAACCCTTGTCATCAACATCATGAGTGAGGGGAAGGCAGAGACCTATGAAGGAGTCTACCAGTG CACTGCAAGGAACGAGCGTGGAGCTGCCGTCTCCAATAACATTGTTGTCCGCCCATCTAGGTCACCCTTG TGGACCAAGGAAAGACTTGAACCTATAGTACTCCAGAATGGGCAGTCATTAGTACTTCCATGTAGGCCTC CGATTGGATTACCTCCGGCCATAATATTTTGGATGGATAATTCCTTTCAGAGACTTCCACAGAGTGAGCG GGTTTCCCAAGGCCTAAATGGAGACCTTTACTTCTCCAATGTCCTCCCAGAGGACACCCGTGAGGACTAT ATCTGCTATGCCAGATTTAATCACACTCAAACCATCCAGCAGAAGCAGCCTATTTCTTTGAAGGTGATTT CAGTGGATGAATTGAATGACACTATAGCTGCTAATTTGAGTGACACTGAGTTTTATGGTGCTAAATCTAG TAAAGAGAGGCCCCCAACGTTTCTAACTCCAGAGGGCAATGAAAGCCACAAAGAGGAATTAAGAGGAAAC GTGCTTTCGCTGGAGTGCATTGCGGAAGGCCTACCTACTCCAATTATTTACTGGATCAAAGAAGACGGAA TGCTTCCCGCCAACCGGACATTTTATCGGAACTTTAAGAAAACCCTGCAGATCACTCATGTTTCCGAAGC CGACTCTGGAAATTATCAGTGCATAGCAAAAAACGCATTAGGAGCCGTCCATCACACCATTTCTGTCACT GTTAAAGCGGCTCCCTACTGGATCGTGGCACCTCAAAACCTCGTGCTTTCCCCGGGAGAGAATGGGACCC TCATCTGCAGAGCTAATGGCAACCCGAAACCCAGAATTAGCTGGTTAACAAATGGAGTCCCAATAGAAAT TGCTCTCGATGACCCCAGCAGAAAAATAGATGGCGATACCATTATATTTTCAAATGTTCAAGAAAGCTCA AGTGCGGTTTATCAGTGCAATGCCTCTAACAAATATGGATATTTACTAGCAAATGCATTTGTAAATGTTC TCGCTGAACCACCTCGGATTCTCACATCAGCAAACACACTGTACCAGGTCATTGCAAACAGGCCTGCTTT GCTAGATTGTGCCTTCTTTGGATCTCCTATGCCTACCATTGAGTGGTTTAAAGGCACTAAAGGAAGCGCT CTTCATGAAGACATTTATGTTTTGCATGATAATGGAACATTAGAAATTCCCGTGGCCCAAAAGGATAGTA CAGGGACGTATACTTGTGTCGCACGGAATAAACTAGGGATGGCAAAGAATGAAGTTCACTTGGAAATCAA AGATCCAACCAGGATCATTAAACAACCTGAGTATGCAGTCGTCCAGAGGGGGAGCAAGGTGTCCTTTGAA TGCAGAGTGAAACATGACCACACCTTAATCCCCACCATTATGTGGCTGAAGGACAATGGAGAGCTGCCCA ATGATGAAAGGTTCTCCACTGACAAGGATCATCTGGTGGTATCTGATGTAAAGGATGACGATGGCGGAAC CTACACGTGTACGGCCAACACAACGCTGGACAGTGCTTCGGCCAGCGCTGTGCTCAGGGTTGTCGATGTC CCGAATCCTCCCTTTGATTTAGAATTGACCAATCAACTTGACAAAAGTGTTCAGCTGACATGGACCCCAG GCGACGACAACAATAGCCCCATTACAAAATTCATCATTGAGTATGAAGATGCAATGCATGATGCAGGGCT GTGGCGCCACCAGGCTGAAGTTTCTGGAACACAGACCACAGCCCAACTGAAGCTGTCTCCCTATGTGAAC TACTCCTTCCGTGTCATGGCAGAGAACAGCATTGGGAGAAGTATGCCGAGCGAGGCATCCGAGCAGTATC TTACAAAAGCCGCAGAACCAGATCAGAATCCCATGGCTGTGGAAGGACTAGGGACAGAGCCGGACAACTT GGTGATTACATGGAAGCCCCTGAATGGTTTTCAATCGAATGGGCCTGGCCTCCAGTACAAAGTGAGCTGG CGCCAGAAAGATGGTGACGATGAGTGGACGTCTGTGGTTGTGGCCAATGTATCCAAATACATTGTTTCTG GCACACCAACCTTTGTCCCATACCTGATAAAAGTTCAAGCTCTGAATGATGTGGGGTTTGCACCAGAGCC AGCTGCAGTCATGGGGCATTCTGGAGAAGACCTTCCAATGGTGGCTCCTGGAAATGTTCGCGTCAGCGTG GTGAACAGTACGCTGGCAGAGGTGCACTGGGACCCAGTTCCTCCCAAGAGTGTCCGAGGACACTTACAAG GCTACCGGATTTACTACTGGAAGACCCAGAGCTCCTCTAAAAGAAACAGGCGCCACATTGAGAAGAAGAT CCTCACCTTCCAGGGCACCAAGACTCACGGCATGCTGCCAGGGCTGCAGCCATACAGTCACTATGCCCTC AACGTCCGAGTGGTCAACGGGAAAGGGGAGGGCCCAGCCAGCACGGACAGAGGCTTCCATACACCGGAGG GAGTCCCTAGTGCTCCCTCATCTTTGAAAATTGTTAATCCCACACTGGACTCCCTCACTTTGGAATGGGA CCCCCCAAGCCACCCAAATGGCATCCTGACTGAGTACATCTTACAATATCAGCCAATTAACAGCACACAT GAGCTAGGCCCTCTGGTAGATTTAAAAATTCCTGCCAACAAGACCCGCTGGACTTTGAAAAATTTAAATT TCAGCACTCGGTACAAGTTCTATTTCTATGCACAGACATCAGTGGGGCCAGGCAGTCAGATCACAGAGGA AGCGATAACGACTGTGGACGAAGGTAAGAAGGCAATGGCAAGCCGGCAAGTGGATATCGCGACCCAAGGC TGGTTCATAGGTCTAATGTGCGCTGTTGCTCTCCTCATCTTAATTTTGCTGATTGTTTGCTTCATCAGAA GAAACAAAGGTGGTAAATACCCAGTTAAAGAAAAGGAGGATGCTCATGCAGACCCTGAAATCCAGCCCAT GAAGGAAGATGATGGGACGTTTGGAGAATACAGTGATGCAGAAGATCACAAGCCTTTGAAAAAAGGAAGT CGAACACCTTCAGACAGGACTGTGAAAAAAGAAGATAGCGATGATAGTCTGGTTGACTATGGAGAGGGGG TGAACGGCCAATTCAACGAGGATGGCTCCTTTATTGGCCAATACAGTGGTAAGAAAGAGAAAGAGCCAGC AGAGGGAAATGAAAGCTCAGAGGCCCCTTCTCCTGTCAACGCAATGAACTCCTTTGTTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001146031 |
| Insert Size | 3561 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001146031.1, NP_001139503.1 |
| RefSeq Size | 7362 bp |
| RefSeq ORF | 3561 bp |
| Locus ID | 319504 |
| UniProt ID | Q810U4 |
| Gene Summary | Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding (PubMed:11564762). Plays a role in mediating cell-cell contacts between Schwann cells and axons (PubMed:20188654). Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters (PubMed:14602817, PubMed:20188654). Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier (PubMed:24719088).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the mid coding region and two alternate in-frame exons in the 3' coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG219512 | Nrcam (tGFP-tagged) - Mouse neuron-glia-CAM-related cell adhesion molecule (Nrcam) transcript variant 2, (10ug) |
CN¥ 13,110.00 |
|
| MR219512 | Nrcam (Myc-DDK-tagged) - Mouse neuron-glia-CAM-related cell adhesion molecule (Nrcam), transcript variant 2 |
CN¥ 11,880.00 |
|
| MR219512L3 | Lenti ORF clone of Nrcam (Myc-DDK-tagged) - Mouse neuron-glia-CAM-related cell adhesion molecule (Nrcam), transcript variant 2 |
CN¥ 13,780.00 |
|
| MR219512L4 | Lenti ORF clone of Nrcam (mGFP-tagged) - Mouse neuron-glia-CAM-related cell adhesion molecule (Nrcam), transcript variant 2 |
CN¥ 13,780.00 |
