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Adcy3 (NM_138305) Mouse Untagged Clone
CAT＃: MC223746
Adcy3 (untagged) - Mouse adenylate cyclase 3 (Adcy3), transcript variant 1, (10ug)
CNY 11,968.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AC3; mKIAA0511 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223746 representing NM_138305
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCGAGGAACCAGGGCTTCTCGGATCCCGAGTACTCGGCAGAGTACTCAGCTGAATACTCGGTCAGCC TGCCCTCTGACCCCGACCGCGGGGTCGGCCGGACCCATGAAATTTCTGTGCGGAACTCGGGGTCCTGCCT GTGCCTGCCTCGCTTTATGCGGCTGACCTTCGTGCCTGAGTCCTTGGAGAACCTCTACCAGACCTACTTC AAAAGGCAGCGCCATGAGACCCTGCTGGTGCTGGTGGTCTTTGCGGCCCTCTTTGACTGCTACGTGGTAG TGATGTGCGCGGTGGTCTTCTCCAGCGACAAGCTGGCGCCCCTCATGGTGGCAGGCTTCGGTCTGGTGTT GGACATCATCCTTTTCGTGCTCTGTAAAAAGGGGCTGCTCCCGGACCGAGTGAGCCGCAAAGTGGTACCC TACCTGCTGTGGCTGCTCATCTCGGCCCAGATCTTCTCCTACCTGGGCCTGAACTTTTCACGGGCCCACG CAGCCAGTGACACTGTGGGTTGGCAGGCTTTCTTTGTCTTCTCCTTCTTCATAACGCTGCCCCTCAGCCT CAGCCCCATCGTGATCATCTCTGTGGTCTCCTGTGTTGTGCACACGCTTGTGTTGGGGGTCACTGTGGCC CAGCAGCAGCAGGATGAGCTGGAAGGGATGCAGCTGCTGAGGGAGATCCTGGCCAACGTCTTCCTCTACC TGTGTGCTATCATCGTGGGCATCATGTCCTACTACATGGCAGACCGCAAGCACCGCAAGGCCTTCCTGGA GGCCCGCCAGTCACTGGAGGTGAAGATGAATCTGGAGGAGCAGAGCCAGCAGCAGGAAAACCTTATGCTT TCCATCCTGCCCAAGCACGTGGCTGACGAGATGCTGAAGGACATGAAGAAGGACGAGAGCCAGAAGGACC AGCAGCAGTTCAATACCATGTACATGTACCGGCACGAGAATGTCAGCATCCTGTTTGCAGATATTGTGGG CTTTACCCAGCTGTCCTCTGCTTGCAGTGCCCAGGAGCTCGTGAAGTTACTCAACGAGCTCTTCGCCCGC TTTGACAAGCTGGCAGCCAAATACCACCAGCTGAGGATCAAGATCCTAGGCGACTGTTACTACTGCATCT GCGGCTTGCCTGACTACCGGGAGGACCATGCCGTGTGCTCCATCCTTATGGGGCTTGCCATGGTAGAGGC CATCTCGTACGTGCGGGAGAAGACCAAGACTGGAGTGGACATGCGTGTGGGAGTGCACACAGGCACTGTC CTAGGCGGTGTCCTGGGCCAGAAGCGCTGGCAGTATGATGTATGGTCTACTGATGTCACCGTGGCAAACA AGATGGAGGCTGGTGGCATCCCAGGGCGCGTGCACATTTCCCAGAGCACCATGGACTGCCTGAAGGGGGA GTTTGATGTGGAGCCTGGTGATGGGGGCAGTCGCTGCGACTACCTAGATGAGAAGGGCATCGAAACCTAC CTCATCATTGCCTCCAAGCCAGAGGTGAAGAAAACAGCCCAAAATGGCCTCAACGGCTCGGCCGTGCCAA ACGGAGCGCCGGCATCCTCCAAACCCAGCTCCCCTGCCCTCATCGAGACCAAGGAGCCCAATGGAAGTGC CCATGCCAGCGGCTCCACATCAGAGGAGGCTGAAGAACAGGAGGCCCAGGCTGACAACCCCTCGTTCCCC AACCCCCGCCGCAGGCTGCGCCTCCAGGACCTGGCGGACCGTGTGGTGGACGCCTCTGAGGATGAGCACG AACTGAACCAGCTGCTTAATGAGGCCCTGCTGGAGCGGGAGTCCGCCCAGGTGGTAAAGAAGAGAAACAC ATTCCTCCTGACCATGAGGTTCATGGACCCAGAGATGGAAACACGCTACTCGGTGGAGAAGGAGAAGCAG AGCGGGGCTGCCTTCAGCTGCTCCTGTGTGGTCCTCTTCTGCACGGCCATGGTGGAGATACTCATTGACC CCTGGCTGATGACAAACTATGTGACCTTTGTGGTTGGGGAGGTTCTGCTCCTGATCCTGACCATCTGCTC GATGGCTGCCATCTTTCCCAGGTCATTTCCCAAGAAGCTTGTGGCCTTCTCATCTTGGATTGACCGGACC CGCTGGGCAAGGAACACCTGGGCCATGTTAGCCATCTTCATTCTGGTTATGGCCAATGTTGTGGACATGC TCAGCTGTCTCCAGTACTACATGGGACCTTACAACATGACAGCTGGGATGGAGCTGGACGGCGGCTGCAT GGAGAACCCCAAGTACTACAACTACGTAGCTGTGCTGTCGCTCATCGCCACCATCATGCTGGTGCAGGTC AGCCACATGGTGAAGCTGACGCTCATGCTGCTCGTCACAGGCGCCGTGACTGCCCTCAACCTGTACGCCT GGTGTCCTGTCTTTGATGAATACGACCACAAGCGCTTTCAGGAAAAGGACTCTCCTATGGTGGCCTTAGA GAAGATGCAGGTACTTGCCACCCCTGGGCTCAATGGCACTGACAGCAGGCTGCCCCTGGTGCCTTCCAAG TACTCCATGACTGTGATGATGTTCGTCATGATGCTGAGCTTTTACTACTTCTCGCGCCACGTGGAAAAAC TGGCCCGAACACTGTTCTTGTGGAAGATTGAGGTCCATGACCAGAAAGAACGTGTCTACGAGATGCGCCG ATGGAACGAGGCCTTGGTCACCAACATGTTGCCTGAGCATGTTGCACGCCATTTTCTGGGGTCCAAGAAG AGAGATGAGGAGCTGTACAGCCAGTCTTATGACGAGATTGGAGTCATGTTTGCCTCCTTGCCCAACTTTG CTGACTTCTACACTGAGGAGAGCATCAACAACGGCGGCATCGAGTGTCTACGCTTCCTCAATGAGATCAT CTCTGATTTTGACTCTCTCCTGGACAATCCCAAATTCCGGGTCATCACCAAGATCAAAACTATTGGCAGC ACCTATATGGCAGCTTCAGGAGTCACACCAGATGTCAACACCAATGGCTTTACAAGCTCCAGCAAGGAGG AGAAGTCAGACAAGGAGCGCTGGCAGCACCTGGCTGACCTGGCTGACTTTGCATTAGCCATGAAGGACAC GCTCACAAACATCAACAACCAGTCATTCAACAACTTCATGTTGCGCATAGGCATGAACAAAGGAGGGGTT CTGGCTGGCGTCATTGGAGCCCGGAAACCACACTATGACATCTGGGGCAATACGGTCAATGTGGCCAGCA GGATGGAATCCACAGGAGTCATGGGCAACATCCAGGTGGTAGAAGAGACGCAGGTCATCCTTCGAGAGTA CGGCTTCCGCTTTGTGAGGCGAGGTCCCATCTTTGTGAAAGGCAAAGGGGAGCTTCTGACCTTTTTCTTG AAGGGGCGGGACAGGCCAGCTGCCTTCCCCAATGGCTCCTCTGTTACACTGCCCCACCAAGTGGTGGACA ACCCCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_138305 |
| Insert Size | 3438 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138305.3, NP_612178.2 |
| RefSeq Size | 4348 bp |
| RefSeq ORF | 3438 bp |
| Locus ID | 104111 |
| UniProt ID | Q8VHH7 |
| Gene Summary | Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:9768837, PubMed:11055432, PubMed:25329148). Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis (PubMed:9768837, PubMed:11055432). Required for the perception of odorants (PubMed:11055432). Required for normal sperm motility and normal male fertility (PubMed:15705663). Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet (PubMed:25329148).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A Gain-of-Function Mutation in Adenylate Cyclase 3 Protects Mice from Diet-Induced Obesity
,Pitman, JL;Wheeler, MC;Lloyd, DJ;Walker, JR;Glynne, RJ;Gekakis, N;,
PLoS ONE
,PubMed ID 25329148
[Adcy3]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG224967 | Adcy3 (tGFP-tagged) - Mouse adenylate cyclase 3 (Adcy3) transcript variant 1, (10ug) |
CNY 12,540.00 |
|
| MR224967 | Adcy3 (Myc-DDK-tagged) - Mouse adenylate cyclase 3 (Adcy3), transcript variant 1 |
CNY 11,944.00 |
|
| MR224967L3 | Lenti ORF clone of Adcy3 (Myc-DDK-tagged) - Mouse adenylate cyclase 3 (Adcy3), transcript variant 1 |
CNY 13,300.00 |
|
| MR224967L4 | Lenti ORF clone of Adcy3 (mGFP-tagged) - Mouse adenylate cyclase 3 (Adcy3), transcript variant 1 |
CNY 13,300.00 |
