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Dlc1 (NM_001194941) Mouse Untagged Clone
CAT＃: MC223647
Dlc1 (untagged) - Mouse deleted in liver cancer 1 (Dlc1), transcript variant 3, (10ug)
CNY 14,350.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | A730069N07Rik; Arhgap7; dlc-1; HP; STARD12 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223647 representing NM_001194941
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGGACCCCGAGGGCCACGTGATGGCTCGGCCCCTGAGAGGCCCGCTGCGGAGGTCCTTCAGCGACC ACATCAGAGACTCCACCGCCAGGGCGCTGGATGCTATCTGGAAAAACACCAGAGAGAGACGGCTAGCAGA AATTGAAGCCAAGGAAGCTTGCGACTGGCTGAGAGTGACTGGTTTCCCCCAGTATGCACAGCTGTATGAA GATCTACTGTTCCCTATTGATATTGCGCTGGTCAAGAGAGAACATGACTTCTTGGACAGAGACGCCATCG AGGCTCTCTGCAGGCGCTTAAATACTCTAAACAAGTGTGCAGTCATGAAGCTGGAGATCAGTCCTCACCG GAAGCGAAGTGAGGATTCGGATGAAGATGAGCCTTGCGCCATAAGCGGCAAGTGGACTTTCCAGAGGGAC AGCAAGCGGTGGTCCCGCCTTGAAGAGTTTGACGTCTTTTCCCCAAAGCAGGATCCAATCCCTGGGTCCC CAGACAACTCTCGTTTGCAAAGCGCCACAAGCCACGAAAGCATGCTGACAGACCTCAGCGAGCACCAGGA GGTGGCCTCTGTCCGAAGCCTCAGCAGCACCAGCAGCAGCGTCCCCACCCACGCAGCCCACAGTGGAGAT GCCACTACGCCCCGAACCAATTCCGTCATCAGCGTCTGCTCCTCCGGACACTTTGTAGGCAATGATGACT CTTTTTCCAGCCTGCCGTCTCCCAAGGAACTGTCCAGCTTCAGTTTTAGCATGAAAGGCCACCACGAGAA GAACACCAAGTCGAAGACGCGGAGCCTGCTCAAACGCATGGAGAGCCTGAAGCTCAAGGGCTCCCACCAC AGCAAGCACAAGGCGCCTTCCAAGCTGGGGTTGATCATCAGTGCTCCCATTCTGCAGGAGGGTATGGATG AGGCAAAGCTGAAGCAGCTGAACTGTGTGGAGATCTCAGCCCTCAATGGCAACCACATCAACGTGCCCAT GGTACGGAAAAGGAGCGTGTCTAACTCCACCCAGACCAGCAGCAGCAGCAGCCAATCAGAGACCAGCAGC GCGGTCAGCACACCCAGCCCGGTCACCAGGACCCGGAGCCTCAGCACCTGTAACAAGCGGGTGGGCATGT ATCTAGAGGGCTTCGACCCATTCAGTCAGTCCACCTTGAACAACGTGACGGAGCAGAACTATAAAAACCG TGAGAGCTACCCAGAGGACACGGTGTTCTACATTCCCGAAGATCACAAGCCCGGCACCTTCCCTAAGGCC CTCTCCCATGGCAGTTTCTGTCCCTCGGGAAACAGTTCTGTGAACTGGAGGACCGGAAGCTTCCATGGCC CTGGCCATCTCAGCCTACGGAGAGAAAACAGCCATGACAGTCCTAAGGAGCTGAAGAGACGCAATTCTTC CAGCTCTCTGAGCAGCCGCCTGAGCATCTATGATAACGTACCGGGTTCTATCCTGTACTCCAGCTCGGGA GAACTGGCCGACCTGGAGAATGAGGACATCTTCCCTGAGCTGGATGACATTCTCTACCACGTGAAGGGGA TGCAGCGGATAGTCAACCAGTGGTCCGAGAAGTTTTCCGACGAGGGAGACTCGGACTCAGCCCTGGACTC TGTCTCTCCTTGCCCGTCATCTCCAAAACAGATACACCTGGATGTGGACCATGACCGAAGGACACCCAGT GACCTGGACAGCACAGGCAACTCCCTCAATGAGCCCGAAGAGCCCACTGATATCCCGGAAAGAAGAGACT CAGGGGTGGGGGCTTCCCTGACCAGGTGCAATAGGCACAGACTGAGGTGGCACAGCTTCCAGAGCTCCCA CCGGCCGAGCCTCAACTCCGTGTCACTGCAGATTAACTGCCAGTCTGTGGCCCAGATGAACCTGCTGCAG AAATACTCGCTCCTGAAATTGACGGCCCTGCTGGAAAAGTACACGCCTTCCAACAAGCACGGCTTCAGCT GGGCTGTGCCCAAGTTCATGAAAAGGATCAAGGTTCCAGACTACAAGGACCGGAGTGTGTTTGGGGTCCC ACTGACTGTGAACGTGCAGCGCTCAGGACAGCCCCTGCCCCAGAGCATCCAGCAGGCCATGCGCTACCTC CGTAACCACTGTCTGGACCAGGTCGGGCTCTTCAGGAAGTCAGGTGTCAAATCCCGGATCCAGGCTCTAC GCCAGATGAATGAAAGCGCTGAAGATAATGTCAACTATGAAGGCCAGTCTGCTTATGATGTGGCAGACAT GTTAAAGCAATATTTTCGAGATCTTCCTGAGCCCCTCATGACGAACAAACTCTCCGAAACCTTCCTGCAG ATCTACCAGTATGTTCCCAAGGACCAGCGCCTCCAAGCCATCAAGGCGGCCATTATGCTCCTGCCCGACG AGAACCGGGAGGTTCTGCAGACACTTCTCTATTTCCTGAGCGATGTCACAGCGGCTGTGAAAGAAAACCA GATGACTCCCACCAACCTGGCTGTGTGCCTAGCTCCGTCCCTCTTCCACCTCAACACCCTGAAGCGAGAG AATTCTTCTCCAAGGGTAATGCAAAGAAAACAGAGTTTGGGCAAACCAGACCAGAAAGACCTGAATGAAA ACCTAGCGGCGACTCAAGGGCTGGCCCACATGATTGCTGAGTGCAAGAAGCTCTTCCAGGTCCCTGAGGA AATGAGCCGGTGCCGTAACTCCTACACTGAACAAGAGCTGAAGCCCCTTACCCTGGAGGCCTTGGGACAC CTGAATAGTGACCAGCCTGCTGACTACAGACACTTCCTCCAGGACTGTGTGGATGGCCTGTTTAAGGAGG TCAAAGAGAAGTTCAAAGGCTGGGTCAGCTACCCCACCTCCGAACAGGCTGAGCTGTCCTATAAGAAGGT CAGCGAAGGACCCCCGTTAAGGCTTTGGAGGTCAACTATCGAAGTCCCCGCTGCACCCGAGGAGATCTTA AAGCGCCTTCTGAAGGAGCAACACCTCTGGGATGTGGACCTGCTGGACTCCAAGGTGATTGAAATCCTGG ACAGCCAGACTGAAATCTACCAATACGTCCAAAACAGCATGGCGCCCCACCCTGCGCGGGACTACGTCGT ATTGAGGACCTGGAGGACTAACTTACCCAGGGGGGCCTGTGCTCTCTTACTCACCTCTGTGGATCACGAC CGGGCCCCCGTGGCGGGGGTGAGGGTTAATGTGCTCCTGTCCAGATATTTGATTGAACCCTGCGGGTCAG GAAAATCCAAGCTTACCTACATGTGCAGAGCTGATTTAAGGGGCCACATGCCGGAGTGGTACTCAAAATC TTTTGGACATTTGTGTGCAGCCGAAGTGGTAAAGATCCGAGACTCCTTCAGTAATCAGAACACTGAAAGC AAGGACACGAGATCTAGGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001194941 |
| Insert Size | 3381 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001194941.1, NP_001181870.1 |
| RefSeq Size | 6266 bp |
| RefSeq ORF | 3381 bp |
| Locus ID | 50768 |
| UniProt ID | Q9R0Z9 |
| Gene Summary | Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG225230 | Dlc1 (tGFP-tagged) - Mouse deleted in liver cancer 1 (Dlc1) transcript variant 3, (10ug) |
CNY 12,350.00 |
|
| MR225230 | Dlc1 (Myc-DDK-tagged) - Mouse deleted in liver cancer 1 (Dlc1), transcript variant 3 |
CNY 11,210.00 |
|
| MR225230L3 | Lenti ORF clone of Dlc1 (Myc-DDK-tagged) - Mouse deleted in liver cancer 1 (Dlc1), transcript variant 3 |
CNY 13,110.00 |
|
| MR225230L4 | Lenti ORF clone of Dlc1 (mGFP-tagged) - Mouse deleted in liver cancer 1 (Dlc1), transcript variant 3 |
CNY 13,110.00 |
