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Adcy7 (NM_001109756) Mouse Untagged Clone
CAT＃: MC223539
Adcy7 (untagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4, (10ug)
CNY 14,060.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA407758 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223539 representing NM_001109756
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCAGCCAAGGGGCGCTACTTCCTAAATGAGGGTGATGAAGGCCCCGACCAGGCAGCGCTCTATGAGA AGTACCGGCTCACCAGCTTGCACGGGCCACTGCTGCTCTTGCTCCTCCTGGTGGCCGCGGCCACCTGCAT TGCGCTCATCAGCATCGCCTTCAGTCATGAGGATCTCCGCAGACACCAGGTTGTCCTGGGCACTGCGTTC CTCATGCTGACGCTGTTTGTGGCTCTCTATGTGCTGGTGTATGTCGAGTGCCTGGTGCAGCGGTGGCTGC GGGCCTTGGCGCTACTCACCTGGGCTTGCCTCATGGTACTAGGCTCCGTGCTGATGTGGGACTCTTTGGA GAATGAAGCCCATGCGTGGGAGCAGGTGCCTTTCTTCCTGTTTGTCGTCTTTGTGGTGTATGCACTACTG CCTCTCAGCAGGAGGGCAGCCATCGTGGCAGGCGTGACCTCCACGGTCTCCCATCTCCTGGTGTTTGGAG CTGTGACAAGAGCCTTCCAGACGTCCATGTCTAGCACTCAACTGGGGCTGCAGCTCCTGGCCAATGCCGT TATCCTCCTGGGTGGGAACTTCACGGGTGCCTTCCACAAGCACCAGCTGCAGGACGCGTCCAGGGATCTC TTTATCTACACCGTCAAATGCATCCAGATCCGTCGGAAGCTTCGTGTGGAGAAGCGCCAGCAGGAGAACC TGCTTCTGTCAGTGCTCCCAGCACACATCTCCATGGGTATGAAGCTGGCCATCATTGAGCGCCTCAAAGA GGGTGGTGACCGACACTACATGCCCGACAACAACTTTCACAGCCTCTATGTCAAGCGGCACCAGAATGTC AGCATCTTGTATGCAGACATCGTGGGCTTCACGAGGCTGGCCAGCGACTGCTCTCCCAAGGAGCTGGTGG TGGTGCTCAACGAGCTGTTTGGGAAGTTTGACCAGATTGCTAAGGCCAATGAGTGCATGCGGATCAAGAT CCTGGGTGACTGTTACTACTGCGTGTCAGGCCTGCCCGTGTCGCTGCCCACACATGCCCGCAACTGTGTG AAGATGGGTCTGGACATCTGCGAGGCCATTAAGCAGGTGCGTGAGGCCACGGGCGTGGACATCAGCATGC GTGTGGGCATTCACTCCGGGAATGTGCTATGTGGGGTCATCGGGCTCCGTAAGTGGCAGTATGATGTGTG GTCCCATGATGTGTCCCTGGCCAACAGGATGGAGGCAGCTGGAGTCCCTGGCCGGGTGCACATCACAGAG GCAACATTGAATCACCTGGACAAGGCATATGAGGTGGAGGATGGGCATGGGGAGCAGCGAGACCCCTATC TGAAAGAGATGAACATCCGAACCTACCTGGTGATCGATCCCCGGAGCCAGCAGCCACCCCCACCCAGCCA CCACCTCTCCAAGCCCAAGGGGGACGCAACTCTGAAGATGCGGGCTTCAGTGCGTGTAACCCGCTATCTG GAGTCTTGGGGGGCAGCAAGGCCCTTTGCACACCTCAACCACCGGGAGAGTGTGAGCAGCAGTGAGACCC CCATCTCCAATGGACGGAGGCAGAAGGCCATTCCTCTGCGTCGACACCGTGCCCCTGATAGGAGTGCATC TCCCAAGGGGCGCTTGGAAGATGACTGTGATGACGAGATGCTGTCAGCCATTGAGGGTCTCAGCTCCACC AGGCCCTGCTGCTCCAAGTCTGATGACTTCCACACCTTTGGTCCCATCTTCTTGGAGAAGGGCTTTGAGC GTGAGTACCGCCTGGTGCCCATCCCCCGGGCTCGCTACGACTTCGCCTGTGCCAGCCTTGTCTTCGTCTG CATCCTGCTTGTCCACCTTCTAGTGATGCCCAGGATGGCAACTCTGGGTGTGTCCTTTGGGTTGGTGGCC TGCCTGCTGGGGCTGGTTCTGAGTTTCTGCTTTGCTACTGAGTTCTCGAGGTGCTTTCCATCCCGAAGTA CACTCCAGGCCATCTCGGAGAGCGTGGAGACGCAGCCCCTGGTCAGGCTTGTCCTGGTTGTGCTGACTGT TGGCAGCCTACTGACTGTCGCCATCATTAACATGCCACTGACGCTTAACCCAGGCCCAGAGCAGCCTGGA GACAACAAGACAAGCCCACTGGCTGCACAGAACAGAGTTGGGACCCCATGTGAGCTCCTCCCGTACTACA CCTGCAGCTGCATCCTGGGCTTCATTGCATGCTCTGTTTTCCTGCGGATGAGCCTAGAGCTGAAGGCCAT GCTGCTGACAGTGGCCTTGGTGGCCTACCTGCTGCTCTTCAACCTCTCCCCATGCTGGCACGTCTCAGGC AACAGCACTGAGACCAACGGGACACAAAGGACACGGCTGCTCCTGTCTGATGCACAAAGCATGCCCAGCC ACACCCTTGCTCCGGGGGCTCGGGAGACTGCCCCTTCTCCCAGTTATTTAGAGAGAGACCTGAAGATCAT GGTTAACTTCTACCTGATCCTGTTCTATGCCACCCTCATCTTGCTGTCTAGACAGATTGACTACTACTGC CGCTTGGACTGTCTGTGGAAGAAGAAGTTCAAAAAGGAGCACGAGGAGTTTGAAACAATGGAGAATGTGA ACCGCCTCCTCCTGGAGAATGTGCTGCCGGCGCACGTGGCTGCCCACTTCATTGGGGACAAGGCAGCAGA GGATTGGTACCATCAATCTTATGACTGTGTCTGTGTCATGTTTGCATCCGTTCCGGACTTCAAAGTGTTC TACACTGAGTGTGATGTCAACAAAGAAGGACTGGAGTGCCTTCGACTGCTGAATGAGATAATTGCTGATT TTGACGAGCTCCTGCTGAAGCCCAAGTTTAGTGGTGTGGAGAAGATCAAGACCATTGGCAGCACCTACAT GGCGGCAGCAGGGCTCAGTGCCCCCTCAGGACATGAGAACCAGGACCTGGAGCGGAAGCACGTGCACATC GGAGTCTTGGTAGAATTTAGCATGGCCCTGATGAGCAAGCTGGATGGGATCAACAGGCACTCCTTCAACT CCTTCCGCCTCCGAGTCGGCATAAACCACGGGCCTGTGATTGCTGGAGTGATTGGAGCACGCAAGCCTCA GTATGACATCTGGGGAAACACAGTCAATGTTGCCAGCCGCATGGAGAGCACCGGAGAGCTTGGGAAAATC CAGGTTACCGAAGAGACATGCACTATCCTCCAGGGACTCGGATATTCGTGTGAATGCCGTGGGCTGATCA ACGTCAAAGGCAAAGGGGAACTGCGGACTTACTTTGTATGTACAGACACTGCCAAGTTTCAAGGGCTGGG GCTAAACTGA AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_001109756 |
| Insert Size | 3300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001109756.1, NP_001103226.1 |
| RefSeq Size | 5937 bp |
| RefSeq ORF | 3300 bp |
| Locus ID | 11513 |
| UniProt ID | P51829 |
| Gene Summary | Catalyzes the formation of cAMP in response to activation of G protein-coupled receptors (Probable). Functions in signaling cascades activated namely by thrombin and sphingosine 1-phosphate and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G alpha protein with GNA13 (PubMed:18541530). Also, during inflammation, mediates zymosan-induced increase intracellular cAMP, leading to protein kinase A pathway activation in order to modulate innate immune responses through heterotrimeric G proteins G(12/13) (PubMed:23178822). Functions in signaling cascades activated namely by dopamine and C5 alpha chain and mediates regulation of cAMP synthesis through synergistic action of the stimulatory G protein with G beta:gamma complex (By similarity). Functions, through cAMP response regulation, to keep inflammation under control during bacterial infection by sensing the presence of serum factors, such as the bioactive lysophospholipid (LPA) that regulate LPS-induced TNF-alpha production. However, it is also required for the optimal functions of B and T cells during adaptive immune responses by regulating cAMP synthesis in both B and T cells (PubMed:20505140).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3 and 4 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226308 | Adcy7 (tGFP-tagged) - Mouse adenylate cyclase 7 (Adcy7) transcript variant 4, (10ug) |
CNY 9,220.00 |
|
| MR226308 | Adcy7 (Myc-DDK-tagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4 |
CNY 7,656.00 |
|
| MR226308L3 | Lenti ORF clone of Adcy7 (Myc-DDK-tagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4 |
CNY 10,260.00 |
|
| MR226308L4 | Lenti ORF clone of Adcy7 (mGFP-tagged) - Mouse adenylate cyclase 7 (Adcy7), transcript variant 4 |
CNY 10,260.00 |
