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Mib1 (NM_144860) Mouse Untagged Clone
CAT＃: MC223183
Mib1 (untagged) - Mouse mindbomb homolog 1 (Drosophila) (Mib1), (10ug)
CNY 13,020.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | DIP-1; E430019M12Rik; Mib; mKIAA1323 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223183 representing NM_144860
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGTAACTCCCGCAACAACCGAGTGATGGTGGAGGGGGTCGGCGCCCGCGTAGTGCGCGGCCCGGACT GGAAGTGGGGCAAGCAGGACGGCGGCGAGGGCCATGTAGGCACTGTACGGAGCTTCGAGAGTCCGGAGGA GGTCGTGGTGGTGTGGGACAACGGCACGGCCGCCAACTACCGCTGCTCAGGGGCCTACGACCTGCGTATC CTGGACAGCGCGCCCACCGGCATCAAGCATGATGGAACTATGTGTGATACCTGCCGCCAGCAACCAATCA TTGGCATTCGATGGAAATGTGCAGAGTGCACCAATTATGATTTGTGCACTGTTTGTTATCATGGAGATAA ACATCACTTAAGGCATCGCTTTTATAGGATTACTACACCAGGAAGTGAACGGGTTCTGTTAGAGTCTCGT AGAAAATCTAAGAAGATTACAGCCAGAGGAATCTTTGCTGGTGCCAGAGTGGTGCGAGGAGTGGACTGGC AGTGGGAAGATCAAGATGGAGGCAATGGGCGTAGAGGAAAGGTCACGGAGATCCAGGACTGGAGTGCATC CAGCCCACACAGTGCAGCCTATGTTCTCTGGGATAACGGTGCTAAGAACCTTTACAGGGTTGGCTTTGAG GGCATGTCTGATCTCAAGTGTGTCCAGGATGCCAAAGGAGGTTCTTTCTACAGAGATCATTGCCCTGTGC TAGGTGAGCAGAATGGCAACAGGAATCCTGGTGGATTGCAGATTGGTGACCTGGTAAATATAGACCTTGA TCTAGAAATTGTCCAGTCTTTACAGCACGGTCATGGAGGATGGACCGATGGCATGTTTGAGACTTTAACT ACAACTGGAACCGTCTGTGGCATTGATGAAGATCATGACATTGTAGTACAGTATCCAAGTGGCAATAGAT GGACTTTCAATCCTGCTGTTCTCACTAAGGCAAACATTGTCCGAAGTGGGGATGCTGCACAGGGTGCAGA AGGAGGCACCTCACAGTTTCAAGTGGGTGATCTTGTGCAAGTTTGTTATGATCTGGAAAGAATTAAACTT CTCCAAAGAGGACATGGTGAATGGGCTGAAGCAATGCTTCCAACTTTAGGTAAAGTTGGCCGAGTACAAC AGATTTATTCGGACAGTGACTTAAAGGTGGAAGTCTGTGGAACATCTTGGACGTATAACCCTGCAGCAGT TTCCAAGGTGGCCCCTGCAGGATCAGCCATTAGCAATGCATCTGGTGAAAGACTCTCCCAGCTTCTGAAG AAATTATTTGAAACCCAAGAATCTGGTGACCTCAATGAAGAGCTGGTTAAGGCTGCTGCCAATGGAGACG TGGCTAAAGTGGAAGATTTGCTGAAAAGACCAGATGTGGATGTAAACGGACAGTGTGCTGGCCACACAGC AATGCAAGCTGCTAGTCAGAACGGACATGTTGATATTTTGAAATTACTTTTGAAGCAAAATGTTGATGTT GAAGCAGAGGATAAAGATGGAGATCGAGCCGTTCACCATGCAGCCTTTGGAGATGAGGGTGCTGTCATAG AAGTCCTACACCGAGGCAGTGCTGACCTGAATGCTCGTAATAAGCGTAGACAGACGCCTCTTCATATTGC TGTCAATAAAGGTCATCTTCAAGTTGTGAAGACTTTGTTGGATTTTGGTTGTCATCCCAGTCTCCAGGAT TCTGAAGGTGACACCCCTCTCCATGATGCCATAAGTAAGAAACGGGATGACATTCTGGCAGTTCTTCTGG AAGCTGGAGCAGATGTGACCATCACGAACAATAACGGGTTCAATGCCCTGCACCATGCTGCACTGAGAGG GAACCCCAGTGCAATGCGTGTTTTACTCTCAAAATTACCAAGACCATGGATTGTGGATGAGAAGAAAGAT GATGGTTATACTGCCTTGCACCTGGCTGCCCTGAATAATCATGTGGAAGTGGCTGAGCTGTTGGTGCATC AGGGAAATGCAAACCTGGATATCCAGAATGTGAACCAGCAAACAGCCCTACACCTTGCTGTTGAACGGCA ACACACCCAGATTGTTAGGCTTTTGGTCCGTGCAGGTGCTAAGCTAGACATTCAGGATAAGGATGGAGAT ACTCCTCTGCATGAAGCTTTGAGACATCATACTTTGTCTCAACTACGTCAGCTACAAGACATGCAAGATG TGGGCAAGGTAGACGCTGCCTGGGAACCTTCAAAAAACACATTAATAATGGGACTTGGTACCCAGGGGGC TGAGAAGAAGAGTGCAGCATCCATTGCGTGTTTCTTGGCAGCCAATGGTGCTGATCTCAGCATTCGAAAT AAGAAGGGTCAGTCACCACTGGATCTCTGTCCTGACCCAAGTCTCTGCAAAGCTTTGGCAAAATGTCATA AGGAAAAAGTCAGTGGCCAAGTGGGTTCTCGGAGTCCTTCTATGATTAGCAACGATTCTGAAACTTTAGA GGAATGTATGGTGTGCTCAGACATGAAGAGAGATACTCTTTTTGGTCCGTGTGGACACATTGCAACCTGT TCTTTGTGTTCCCCTCGTGTCAAGAAATGCCTCATTTGTAAAGAGCAGGTTCAGTCCAGGACAAAGATTG AAGAATGTGTGGTGTGCTCCGACAAGAAAGCAGCTGTTCTCTTTCAACCTTGTGGGCACATGTGTGCTTG TGAGAACTGTGCCAGCCTGATGAAAAAGTGTGTGCAGTGTCGGGCAGTGGTTGAGCGGAGGGTGCCTTTC ATCACGTGCTGTGGTGGCAAGAGCTCAGAAGACCCCTCTGATGAAATCTCAAGTGGGAATATCCCAGTGC TGCAGAAGGACAAAGACAACACCAATGTTAACGCAGATGTGCAGAAACTGCAGCAGCAGCTTCAGGACAT TAAGGAGCAGACCATGTGCCCTGTGTGCTTGGATCGCCTGAAGAACATGATTTTCCTCTGTGGCCATGGA ACATGCCAGCTCTGTGGAGACCGGATGAGTGAATGCCCAATTTGTCGCAAGGCAATTGAACGAAGGATTC TTTTGTACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_144860 |
| Insert Size | 3021 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_144860.2, NP_659109.2 |
| RefSeq Size | 3793 bp |
| RefSeq ORF | 3021 bp |
| Locus ID | 225164 |
| UniProt ID | Q80SY4 |
| Gene Summary | E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation (By similarity). Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227236 | Mib1 (tGFP-tagged) - Mouse mindbomb homolog 1 (Drosophila) (Mib1), (10ug) |
CNY 9,220.00 |
|
| MR227236 | Mib1 (Myc-DDK-tagged) - Mouse mindbomb homolog 1 (Drosophila) (Mib1) |
CNY 7,016.00 |
|
| MR227236L3 | Lenti ORF clone of Mib1 (Myc-DDK-tagged) - Mouse mindbomb homolog 1 (Drosophila) (Mib1) |
CNY 10,260.00 |
|
| MR227236L4 | Lenti ORF clone of Mib1 (mGFP-tagged) - Mouse mindbomb homolog 1 (Drosophila) (Mib1) |
CNY 10,260.00 |
