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Ephb4 (NM_010144) Mouse Untagged Clone
CAT＃: MC222990
Ephb4 (untagged) - Mouse Eph receptor B4 (Ephb4), transcript variant 2, (10ug)
CNY 7,240.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI042935; Htk; MDK2; Myk1; Tyro11 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222990 representing NM_010144
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGCTCCGAGCGCTGCTGTGCTGGGCTTCCCTCGCCACTGCTTTAGAAGAGACCCTGTTGAACACAA AACTGGAAACGGCGGATCTGAAATGGGTGACTTACCCTCAGGCAGAGGGCCAGTGGGAGGAGCTAAGCGG CCTGGATGAGGAACAGCACAGCGTCCGCACCTATGAGGTGTGCGACATGAAGCGTCCAGGGGGCCAGGCT CACTGGCTGCGCACTGGCTGGGTCCCAAGGCGAGGTGCTGTCCACGTGTATGCCACGATACGCTTCACCA TGATGGAATGCCTGTCCCTGCCGAGGGCCAGTCGCTCCTGCAAGGAGACATTCACTGTCTTCTATTACGA GAGCGAAGCTGATACGGCCACGGCCCATACGCCCGCCTGGATGGAGAACCCCTACATCAAGGTGGACACA GTGGCCGCAGAACATCTGACTCGGAAGCGCCCTGGAGCTGAAGCCACAGGGAAAGTTAATATCAAGACGC TGCGCCTGGGTCCTCTCAGCAAAGCTGGCTTCTACCTGGCTTTCCAGGACCAAGGAGCCTGCATGGCTCT GCTCTCCCTGCATCTCTTTTACAAGAAGTGCTCCTGGCTGATCACGAACTTGACCTACTTCCCCGAGACG GTGCCTCGGGAGCTCGTGGTGCCGGTGGCAGGTAGCTGCGTGGCCAACGCGGTCCCTACCGCCAACCCCA GCCCCAGCCTCTACTGCCGGGAAGATGGTCAATGGGCTGAGCAGCAGGTCACGGGCTGCAGCTGCGCGCC AGGGTACGAGGCTGCGGAAAGCAACAAAGTATGCAGAGCCTGTGGCCAGGGAACCTTCAAGCCCCAAATA GGAGACGAGTCCTGCCTGCCATGCCCAGCCAACAGCCACTCGAATAACATTGGGTCTCCTGTCTGCCTGT GTCGAATTGGGTATTACCGGGCCCGCTCAGACCCCCGGAGTTCACCTTGCACTACCCCACCCTCTGCTCC AAGAAGCGTGGTTCACCATTTGAATGGTTCCACCCTGCGCCTGGAATGGAGTGCTCCCCTTGAGTCCGGA GGCCGAGAGGACCTCACTTATGCTGTACGCTGCCGAGAGTGCCGTCCTGGGGGTTCCTGCTTGCCCTGTG GGGGCGACATGACCTTCGACCCCGGTCCTCGAGACCTGGTTGAGCCCTGGGTGGCAATCCGAGGGCTGCG TCCTGATGTCACCTATACCTTTGAGGTTGCTGCTTTGAATGGTGTGTCTACCTTAGCCACTGGACCACCT CCTTTTGAGCCTGTCAATGTCACCACTGACCGTGAGGTGCCTCCTGCAGTGTCTGACATCCGAGTGACTC GGTCGTCACCCAGCAGCTTGATCCTGTCATGGGCTATCCCCAGAGCACCCAGTGGGGCCGTGCTGGACTA CGAGGTCAAGTATCATGAGAAGGGCGCAGAGGGCCCCAGCAGTGTTCGTTTCCTGAAGACATCAGAAAAC CGAGCTGAGCTCCGGGGGCTGAAGCGGGGAGCCAGCTATCTGGTCCAGGTACGCGCACGGTCCGAGGCTG GCTACGGTCCCTTCGGCCAGGAGCATCACAGTCAGACTCAACTGGATGAGAGCGAGAGCTGGCGGGAGCA GCTGGCCCTGATTGCAGGCACTGCGGTTGTGGGTGTGGTCCTGGTCCTGGTGGTCGTCATCATTGCAGTT CTCTGCCTCAGGAAGCAGAGCAATGGGAGGGAAGTTGAGTACTCGGATAAGCATGGGCAGTATCTCATCG GGCACGGTACCAAGGTCTACATTGATCCTTTTACTTACGAAGACCCTAATGAGGCAGTGAGGGAATTTGC CAAAGAGATCGATGTCTCCTATGTCAAGATTGAAGAGGTAATTGGTGCAGGTGAGTTCGGCGAGGTGTGC CGGGGTCGGCTGAAGGCACCAGGGAAAAAGGAGAGCTGTGTGGCCATCAAGACTCTGAAGGGTGGCTACA CCGAGCGCCAGAGGCGTGAGTTCCTGAGCGAGGCCTCCATCATGGGCCAGTTCGAGCATCCCAACATCAT CCGCCTCGAGGGCGTGGTCACCAACAGTGTGCCGGTTATGATCCTCACGGAATTCATGGAGAACGGAGCC CTGGACTCCTTCCTGCGGCTGAACGACGGGCAGTTCACAGTCATCCAGCTGGTGGGCATGCTGAGGGGCA TCGCCTCGGGCATGCGGTACCTGGCTGAAATGAGCTATGTCCACCGAGACCTGGCTGCTCGGAACATCTT GGTCAACAGTAACCTGGTCTGCAAGGTGTCCGACTTTGGCCTCTCCAGATTCTTGGAGGAGAACTCCTCT GATCCCACCTACACAAGTTCCCTGGGAGGCAAGATTCCCATCCGATGGACCGCCCCTGAAGCCATTGCCT TCAGGAAGTTCACCTCTGCCAGTGATGCCTGGAGCTATGGGATCGTCATGTGGGAGGTCATGTCTTTTGG GGAACGGCCATACTGGGACATGAGCAACCAGGATGTGATCAATGCCATTGAACAGGACTACCGGCTGCCT CCTCCTCCAGACTGCCCCACCTCCCTCCACCAGCTCATGCTGGATTGTTGGCAGAAGGACCGGAATGCCC GGCCCCGCTTTCCCCAGGTGGTCAGCGCTCTGGACAAGATGATCCGGAATCCCGCTAGCCTCAAAATCGT GGCCAGGGAGAATGGCGGGGCCTCACATCCACTCTTGGACCAACGGCAGCCTCACTATTCTGCTTTCGGT TCTGTGGGCGAGTGGCTTCGAGCCATCAAGATGGGAAGATACGAGGAAAGTTTTGCAGCGGCTGGATTCG GCTCCTTTGAGGTGGTCAGTCAGATCTCTGCCGAGGACCTTCTCCGAATTGGAGTCACTCTGGCAGGACA CCAGAAGAAAATCTTGGCCAGTGTGCAGCATATGAAGTCCCAAGCTAAGCCAGGAGCCCCTGGTGGGACA GGGGGACCAGCCCAGCAGTTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_010144 |
| Insert Size | 2964 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_010144.6, NP_034274.4 |
| RefSeq Size | 4334 bp |
| RefSeq ORF | 2964 bp |
| Locus ID | 13846 |
| UniProt ID | P54761 |
| Gene Summary | Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. This results in a shorter protein (isoform b) compared to isoform a. |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211390 | Ephb4 (tGFP-tagged) - Mouse Eph receptor B4 (Ephb4) |
CNY 7,890.00 |
|
| MR211390 | Ephb4 (Myc-DDK-tagged) - Mouse Eph receptor B4 (Ephb4), transcript variant 2 |
CNY 7,232.00 |
|
| MR211390L3 | Lenti ORF clone of Ephb4 (Myc-DDK-tagged) - Mouse Eph receptor B4 (Ephb4), transcript variant 2 |
CNY 9,030.00 |
|
| MR211390L4 | Lenti ORF clone of Ephb4 (mGFP-tagged) - Mouse Eph receptor B4 (Ephb4), transcript variant 2 |
CNY 9,632.00 |
