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Ddr1 (NM_007584) Mouse Untagged Clone
CAT＃: MC222504
Ddr1 (untagged) - Mouse discoidin domain receptor family, member 1 (Ddr1), transcript variant 1, (10ug)
CNY 10,016.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 6030432F18; AI323681; Cak; CD167a; Nep; PTK3A |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222504 representing NM_007584
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGACAGGGACCCTCTCATCTCTACTGCTGCTGCTACTCTTGGTGACAATTGGAGATGCTGACATGA AGGGACATTTTGACCCTGCCAAGTGCCGCTATGCCCTGGGCATGCAGGACCGCACCATTCCTGACAGCGA TATCTCTGTGTCCAGCTCCTGGTCGGACTCTACCGCTGCCCGCCACAGCAGGCTGGAAAGCAGTGATGGA GATGGGGCTTGGTGCCCTGCAGGGCCTGTGTTCCCCAAAGAAGAGGAGTACTTGCAGGTGGACCTTCGTA GGCTACACCTGGTGGCTCTGGTGGGCACCCAGGGCCGCCATGCTGGGGGTCTGGGCAAAGAGTTCTCCCG AAGCTATCGGTTGCGTTACTCCCGAGATGGCCGCCGCTGGATGGACTGGAAGGACCGCTGGGGACAGGAG GTGATTTCGGGTAACGAGGATCCCGGGGGAGTAGTGCTGAAGGACCTTGGGCCCCCCATGGTGGCCCGGC TGGTCCGCTTCTACCCCAGGGCTGACCGGGTCATGAGTGTCTGTCTTCGGGTGGAGCTCTATGGCTGCCT CTGGCGGGATGGACTCCTGTCATATACAGCCCCCGTGGGGCAGACCATGCAGTTATCTGAGGTGATGGTA CATCTCAATGATTCCACTTACGATGGATATACTGCTGGAGGGCTGCAGTATGGCGGTCTGGGCCAGCTGG CAGATGGCGTGGTGGGCCTGGATGATTTCAGGCAGAGCCAGGAGCTGCGGGTCTGGCCAGGCTATGACTA TGTGGGATGGAGCAATCAGAGCTTCCCCACGGGCTACGTGGAGATGGAGTTTGAGTTTGATCGGTTGAGG ACCTTCCAGACCATGCAGGTCCACTGTAACAACATGCACACTCTGGGAGCCCGCCTACCAGGCGGGGTGG AATGCCGGTTTAAAAGGGGTCCCGCCATGGCCTGGGAAGGAGAGCCTGTCCGCCATGCTCTGGGAGGCAG CCTTGGAGACCCCAGAGCCCGGGCCATCTCAGTGCCCCTGGGTGGCCACGTGGGCCGCTTTCTGCAGTGC AGATTCCTCTTTGCAGGTCCTTGGTTACTCTTCAGTGAGATCTCTTTCATCTCAGATGTGGTGAACGACT CCTCTGACACCTTCCCACCAGCCCCCTGGTGGCCACCTGGCCCGCCTCCCACCAACTTCAGCAGCTTGGA GCTGGAGCCCCGGGGTCAACAGCCAGTGGCCAAGGCGGAGGGGAGCCCAACTGCCATCCTCATTGGCTGC CTGGTGGCCATCATCCTGCTGCTGCTTCTCATCATCGCGCTGATGCTCTGGAGGCTGCACTGGCGCCGGC TGCTCAGCAAGGCTGAGCGCCGCGTGTTGGAGGAGGAGCTGACGGTTCACCTTTCTGTCCCTGGGGACAC CATCCTCATCAACAACCGCCCAGGACCCCGAGAGCCACCCCCTTACCAGGAGCCCCGGCCTCGGGGGACT CCACCCCATTCTGCACCCTGCGTCCCCAACGGCTCTGCGTTGCTGCTCTCCAATCCGGCCTACCGCCTCC TTCTGGCCACTTACGCCCGTCCCCCTCGAGGCCCGGGCCCCCCCACACCCGCCTGGGCCAAACCCACCAA CACCCAGGCCTGCAGTGGGGACTATATGGAGCCCGAGAAGCCGGGTGCCCCGCTTCTACCCCCACCTCCC CAGAACAGCGTCCCCCATTATGCCGAAGCTGACATTGTCACCCTGCAGGGCGTCACTGGGGGCAACACCT ACGCTGTGCCTGCACTGCCCCCAGGGGCGGTTGGGGATGGGCCCCCCAGAGTGGATTTCCCTCGGTCACG GCTCCGCTTCAAGGAGAAGCTTGGCGAGGGCCAATTTGGGGAGGTACACCTGTGTGAAGTAGAGGACCCG CAAGATCTGGTCAGTAGTGACTTCCCTATCAGTGTGCACAAGGGACACCCCTTGCTGGTAGCAGTGAAGA TCCTCCGGCCAGATGCCACCAAAAATGCCAGGAATGATTTCCTGAAGGAGGTAAAGATCATGTCACGGCT GAAGGACCCAAACATCATCCGGCTCCTGGGTGTGTGTGTGCAGGATGACCCCCTCTGCATGATCACAGAC TACATGGAGAACGGCGATCTGAACCAGTTCCTCAGTGCCCGCCAGCTGGAGAACAAGGCCACTCAGGGGC TCTCTGGGGACACAGAGTCTGACCAGGGGCCCACAATCAGCTACCCTATGCTGTTACACGTGGGGGCCCA GATCGCCTCTGGCATGCGTTATCTCGCCACGCTGAACTTTGTGCATCGGGACCTGGCCACCCGGAACTGC TTGGTTGGGGAAAATTTCACCATCAAAATCGCCGACTTTGGCATGAGCCGGAATCTCTACGCTGGGGATT ATTACCGTGTCCAGGGCCGGGCGGTGCTGCCCATCAGGTGGATGGCTTGGGAGTGCATTCTCATGGGGAA GTTCACAACAGCCAGTGACGTTTGGGCCTTCGGAGTGACCCTGTGGGAGGTGCTGATGCTCTGCAGGTCC CAGCCCTTTGGGCAGCTTACAGATGAGCAGGTTATCGAGAATGCCGGCGAGTTCTTCAGGGACCAGGGCC GGCAGGTCTACTTGTCCAGGCCACCCGCCTGCCCACAGACCCTGTATGAGCTGATGCTCCGGTGTTGGAG CCGGGAGCCCGAGCAGCGGCCGCCCTTCGCCCAGCTTCATCGGTTCCTGGCGGATGATGCGCTCAACACG GTGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_007584 |
| Insert Size | 2736 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007584.2, NP_031610.1 |
| RefSeq Size | 3814 bp |
| RefSeq ORF | 2736 bp |
| Locus ID | 12305 |
| UniProt ID | Q03146 |
| Gene Summary | Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing, but also tumor cell invasion. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Phosphorylates PTPN11 (By similarity). Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Variants 1, 3, and 4 encode the same protein (isoform 1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223468 | Ddr1 (tGFP-tagged) - Mouse discoidin domain receptor family member 1 (Ddr1) transcript variant 1, (10ug) |
CNY 11,608.00 |
|
| MR223468 | Ddr1 (Myc-DDK-tagged) - Mouse discoidin domain receptor family, member 1 (Ddr1), transcript variant 1 |
CNY 10,008.00 |
|
| MR223468L3 | Lenti ORF clone of Ddr1 (Myc-DDK-tagged) - Mouse discoidin domain receptor family, member 1 (Ddr1), transcript variant 1 |
CNY 11,020.00 |
|
| MR223468L4 | Lenti ORF clone of Ddr1 (mGFP-tagged) - Mouse discoidin domain receptor family, member 1 (Ddr1), transcript variant 1 |
CNY 11,020.00 |
