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Fer (NM_001037997) Mouse Untagged Clone
CAT＃: MC221849
Fert2 (untagged) - Mouse fer (fms/fps related) protein kinase, testis specific 2 (Fert2), transcript variant 1, (10ug)
CNY 10,550.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AV082135; C330004K01Rik; Fert; Fert2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221849 representing NM_001037997
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGATTTGGGAGTGACCTGAAGAACTCACAGGAAGCTGTGTTAAAGTTGCAAGACTGGGAACTACGGT TGCTGGAGACAGTGAAGAAATTTATGGCTCTGAGAATAAAGAGTGATAAAGAATATGCATATACTCTACA GAATCTTTGTAATCAAGTTGATAAAGAAAGCACTGTGCAAGTGAATTATGTCAGCAACGTGTCCAAGTCT TGGCTACTGATGATTCAGCAGACAGAACAGCTTAGTAGGATAATGAAGACACATGCAGAGGACTTGAACT CTGGACCCTTGCACAGGCTCACCATGATGATCAAGGACAAGCAGCAAGTGAAGAAGAGCTATGTAGGCAT TCATCAACAGATAGAGGCAGAGATGATCAAGGTCACAAAGACAGAATTGGAGAAATTAAAATCCAGCTAT CGACAATTAATAAAAGAAATGAATTCTGCCAAAGAGAAATATAAAGAAGCCTTAGCGAAAGGGAAGGAAA CAGAAAAGGCCAAGGAGCGCTATGACAAAGCTACAATGAAGCTTCATATGCTGCATAATCAGTATGTGTT GGCACTGAAGGGGGCACAGCTCCATCAGAGCCAGTACTATGATACCACACTTCCTCTGCTGCTGGACTCC GTGCAAAAGATGCAAGAAGAAATGATAAAAGCACTAAAAGGTATATTTGATGACTATAGCCAGATAACCA GCCTTGTTACAGAGGAAATAGTGAATGTCCATAAAGAGATTCAAATGTCTGTTGAACAGATAGACCCTAG CACCGAATATAATAATTTCATAGATGTTCACAGAACAACAGCTGCTAAAGAACAAGAAATCGAATTTGAT ACTTCCCTATTAGAAGAAAATGAAAATCTTCAGGCAAATGAGATCATGTGGAATAATTTAACAGCAGACA GTTTGCAAGTCATGTTGAAGACTTTAGCGGAAGAGCTCACACAGACCCAGCAGATGCTTTTACACAAGGA GGCGGCCGTCCTGGAGCTAGAGAAGAGGATTGAAGAATCTTTTGAGACCTGTGAAAAGAAGTCTGACATT GTGCTTCTTCTGGGCCAAAAACAGGCACTTGAAGAGTTGAAACAGTCAGTCCAGCAGTTGCGATGCACTG AGGCAAAGTGTGCAGCACAGAAAGCTTTGCTGGAGCAAAAAGTACAGGAAAATGATGGGAAAGAACCACC TCCTGTGGTGAATTACGAAGAAGACGCGCGGTCAGTCACATCCATGGAAAGAAAGGAGAGGCTATCCAAA TTTGAGTCTATTCGTCATTCAATTGCTGGGATAATTAAGTCTCCAAAGTCGGTACTCGGATCTTCAACAC AGGTGTGTGATGTGATCTCTGTGGGTGAGAGGCCCCTGGCGGAGCATGACTGGTACCATGGTGCCATCCC CAGGATAGAGGCACAGGAACTGCTGAAGCAGCAAGGAGACTTCCTGGTGCGGGAGAGCCATGGGAAACCT GGTGAATATGTCCTTTCTGTATATTCTGACGGACAAAGGAGGCACTTTATCATACAATTTGTCGATAATC TGTATCGATTCGAGGGCACCGGGTTTTCAAACATTCCCCAGCTTATAGATCACCACTTCAATACAAAGCA AGTCATCACCAAGAAGTCTGGGGTGGTTCTGCTCAACCCCATCCCAAAGGATAAGAAATGGGTTCTCAAT CATGAAGATGTTTCATTGGGAGAATTACTGGGCAAGGGGAATTTTGGTGAAGTGTATAAGGGCACACTAA AGGATAAAACTCCTGTTGCCATTAAAACGTGCAAGGAAGACCTTCCTCAGGAATTAAAAATAAAGTTTCT ACAGGAAGCCAAAATTCTGAAGCAATATGATCATCCCAATATTGTCAAACTGATAGGCGTGTGCACACAA AGACAGCCTGTCTACATCATTATGGAACTGGTCCCAGGGGGTGATTTTCTGACCTTCCTGAGGAAGAGGA AGGACGAGCTGAAGCTGAAGCAGTTGGTGAGATTTTCCTTGGACGTTGCTGCTGGCATGTTGTATCTCGA GAGCAAGAACTGCATTCACAGGGACCTGGCTGCACGGAACTGCCTGGTGGGTGAAAATAATACTCTGAAA ATCAGTGACTTTGGAATGTCTCGGCAAGAAGACGGTGGAGTGTATTCATCTTCTGGCTTAAAGCAGATTC CTATTAAATGGACAGCACCGGAAGCTCTTAATTATGGGAGATACAGTTCTGAAAGTGACGTGTGGAGCTT CGGCATCCTCCTCTGGGAGACCTTCAGCCTAGGAGTCTGCCCGTACCCTGGAATGACAAACCAGCAAGCG CGAGAGCAAGTGGAGAGAGGATACCGGATGTCAGCCCCACAGAACTGTCCAGAGGAGGTTTTTACAATCA TGATGAAGTGTTGGGATTACAAGCCTGAAAACCGCCCTAAGTTCAACGACCTTCACAAAGAGCTCACTGT CATCAAGAAGATGATCACATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001037997 |
| Insert Size | 2472 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001037997.3, NP_001033086.2 |
| RefSeq Size | 3120 bp |
| RefSeq ORF | 2472 bp |
| Locus ID | 14158 |
| UniProt ID | P70451 |
| Gene Summary | Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3 according to PubMed:10878010 and PubMed:19159681, but clearly plays a redundant role in STAT3 phosphorylation. According to PubMed:11134346, cells where wild type FER has been replaced by a kinase-dead mutant show no reduction in STAT3 phosphorylation. Phosphorylates TMF1. Isoform 3 lacks kinase activity.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest isoform (a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG220921 | Fert2 (tGFP-tagged) - Mouse fer (fms/fps related) protein kinase testis specific 2 (Fert2) transcript variant 1, (10ug) |
CNY 9,030.00 |
|
| MR220921 | Fert2 (Myc-DDK-tagged) - Mouse fer (fms/fps related) protein kinase, testis specific 2 (Fert2), transcript variant 1 |
CNY 8,170.00 |
|
| MR220921L3 | Lenti ORF clone of Fert2 (Myc-DDK-tagged) - Mouse fer (fms/fps related) protein kinase, testis specific 2 (Fert2), transcript variant 1 |
CNY 10,070.00 |
|
| MR220921L4 | Lenti ORF clone of Fert2 (mGFP-tagged) - Mouse fer (fms/fps related) protein kinase, testis specific 2 (Fert2), transcript variant 1 |
CNY 10,070.00 |
