Dennd1b (NM_001166501) Mouse Untagged Clone
CAT#: MC221470
Dennd1b (untagged) - Mouse DENN/MADD domain containing 1B (Dennd1b), transcript variant 1, (10ug)
CNY 9,880.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 4632404N19Rik; 4930467M19Rik; 6820401H01Rik; F730008N07Rik |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC221470 representing NM_001166501
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACCGCAGGACCAGGGAAAATCCAGAAAGAACTTTTGACTTGGTATTGAAAGTGAAGTGTCATGCCT CTGAAAATGAAGATCCTGAGGTATTGTGGAAATTCCCAGAGGACTTTGGAGACCAGGAAGTTCTGCAGAG CGTGCCCAAGTTCTGTTTTCCCTTCGATGTGGAAAGGGTGTCTCAGAATCAAGTTGGACAGCACTTTACC TTCGTCCTGACAGACATGGAAAGTAAGCAGCGATTTGGGTTCTGCAGGCTCACATCTGGAGGCAGAATTT GTTTATGTATTCTTAGTTACTTGCCATGGTTTGAAGTATATTATAAACTTCTAAATACTCTGGCAGATTA CTTGGCCAAGGAACTGGAAGAGGATTTGAATGAAACTCTTAAATCACTCTATAACCACCCAGTACCAAAG GCAAACACTCCTGTCAACTTGAGTGTGCACTCCTGTTTCATCACACCTGACATAACTGGACTCCCAACGA TACCGGAGAGTAGAAACCTGACCGAGTACTTTGTTGCCGTGGATGTCAACAACATGCTGCGACTGTACGC CAGCATGCTGCATGAGAGGCGCATCATTATTACCTCGAGCAAATTAAGCACTTTAACTGCCTGTCTCCAT GGATCGGCTGCGCTACTCTACCCGATGTACTGGCAACACATATATATCCCCGTGCTTCCTCCACACCTGC TGGACTACTGCTGTGCCCCAATGCCATACCTGATTGGAATACACTCCAGTCTCATAGAGAGAGTGAAAAA TAAATCATTGGAAGATGTGGTTGTGTTAAATGTTGACACAAACACGTTAGAATCACCATTTAATGACTTG AGCAGCCTGCCCAGTGATGTGGTCTCGGCCTTGAAAAATAAGCTGAAGAAGCAGTCCACAGCTACGGGAG ATGGAGTGGCTCGGGCCTTTCTGAGGGCTCAGGCGGCTTTGTTTGGCTCCTACCGAGATGCTCTGAGATA CAAGCCTGGCGAGCCCATCACCTTCTGTGAGGAGAGCTTTGTAAAGCACCGCTCAAGCGTGATGAAACAG TTCCTGGAGACTGCAGTTAACCTTCAGCTCTTTAAGCAGTTTATTGATGGTCGACTGGCAAAGCTTAACG CAGGAAGAGGTTTCTCTGATATCTTCGAAGAAGAGATCACTTCGGGTGGCTTCTGTGGAGGGAGCCCGAG GTCATATCAGCAGTGGGTGTATACAGTCAAGAAAGGAGGTGCATTGTTCAACACAGCAGTGACCAAAGCA ACTCCCGCTGTGCGGACTGCATACAAATTTGCAAAGAGTCACGCCAGACTGGGACTAAAGGAGGTGAAGA GCAGGCTGAAACACAAGGACAATGAGGAAGAGTATGGGACCTGTTCTGGTTTGGTGCAGTATACACCAGT GTACACTTTACACAATGAAAAGGGAGAGAACAGAGAGAAGCACAAGCTTTCCCAGACACACTTGAAAAGG CCTCATAAGAGCCTAGATGGTACCCTGTATGATGATGATGATGATGACGATGACATTGAACGGGCAAGCA AGATATCTTCTGAAGACGGGGAAGAAACCCGTGCTTATTTCTACGAAAGCGATGACTCCGTTGAAGCCCA GGTGAAGGCTCCTTACTCAGGGGAGATGGACTTACTGGGTGAGATCCTGGACACGCTGAGCACGCACAGC TCTGATCAAGGAAAGCTGGCGCCTGCCAAGAGCCTGGATTTCTTCAGATCCATGGATGACATTGATTACA AGCCTACGAACAAGTCCAACGCTCCCAGTGAGAATAACCTGGCCCTGCTGTGTGCTTCTGGAGACCAGGG AGAGTGGAATCTCGGGCAGGACGACAGCGCCCTCCATGGCAGGCAACTCCCTCCATCCCCAAGGAAACGC GTTTCCTCTGGTGGGCTGACAGAGTCTCTGTTTATCCTGAAAGAGGAGAGCAGGGAGAAGCCCCTCTGTG CTGACAGCGTAAGTGGCCCTACTGTGGTGGGAAAGCCAGCTCCGACTTCAGGACTGCGTTCCCAGCCTGC TGCTCCTGAAGCTTCCCAAACAGAGAGAGGAAGAGCAGAAGTGAAGCAAACACCAGGTCAGGCTCCACTT CAGTCAGAGGATCTGTCGGTGCCCGGCCCCGGGAGCCGCCAGTCGACTTTTGTTCCCTGGGAGAAGGCTG GCAAAGAGGACACGAAGCCTTCAAAGGATGTCGGACTTCTCCAAGAAGTAGTGTCATTGTGTCACATGTC ATGTGACTTCCAACAAGATTTAAACATTTCAGAAGAAAGCAGAAGTGGAAACCAAACTTAG AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-RsrII |
ACCN | NM_001166501 |
Insert Size | 2301 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001166501.1, NP_001159973.1 |
RefSeq Size | 8206 bp |
RefSeq ORF | 2301 bp |
Locus ID | 329260 |
UniProt ID | Q3U1T9 |
Gene Summary | Guanine nucleotide exchange factor (GEF) for RAB35 that acts as a regulator of T-cell receptor (TCR) internalization in TH2 cells. Acts by promoting the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Plays a role in clathrin-mediated endocytosis. Controls cytokine production in TH2 lymphocytes by controlling the rate of TCR internalization and routing to endosomes: acts by mediating clathrin-mediated endocytosis of TCR via its interaction with the adapter protein complex 2 (AP-2) and GEF activity. Dysregulation leads to impaired TCR down-modulation and recycling, affecting cytokine production in TH2 cells.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG216682 | Dennd1b (tGFP-tagged) - Mouse DENN/MADD domain containing 1B (Dennd1b) transcript variant 1, (10ug) |
CNY 7,208.00 |
|
MR216682 | Dennd1b (Myc-DDK-tagged) - Mouse DENN/MADD domain containing 1B (Dennd1b), transcript variant 1 |
CNY 5,608.00 |
|
MR216682L3 | Lenti ORF clone of Dennd1b (Myc-DDK-tagged) - Mouse DENN/MADD domain containing 1B (Dennd1b), transcript variant 1 |
CNY 8,550.00 |
|
MR216682L4 | Lenti ORF clone of Dennd1b (mGFP-tagged) - Mouse DENN/MADD domain containing 1B (Dennd1b), transcript variant 1 |
CNY 8,550.00 |
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