Dlg4 (NM_001109752) Mouse Untagged Clone

CAT#: MC221073

Dlg4 (untagged) - Mouse discs, large homolog 4 (Drosophila) (Dlg4), transcript variant 2, (10ug)



  "NM_001109752" in other vectors (3)

CNY 5,816.00

CNY 9,310.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms Dlgh4; PSD-95; PSD95; SAP90; SAP90A
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC221073 representing NM_001109752
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGACTGTCTCTGTATAGTGACAACCAAGAAATACCGCTACCAAGATGAAGACACGCCCCCTCTGGAAC
ACAGCCCGGCCCACCTCCCCAACCAGGCCAATTCTCCCCCTGTGATTGTCAACACGGACACCCTAGAAGC
CCCAGGATATGTGAACGGAACAGAGGGGGAGATGGAGTATGAGGAGATCACATTGGAAAGGGGTAACTCA
GGTCTGGGCTTCAGCATCGCAGGTGGCACCGACAACCCACACATCGGTGACGACCCATCCATCTTTATCA
CCAAGATCATTCCTGGTGGGGCTGCAGCCCAGGATGGCCGCCTCAGGGTCAACGACAGCATCCTGTTTGT
CAATGAAGTGGATGTCCGGGAGGTGACCCATTCAGCTGCAGTGGAGGCCCTCAAAGAGGCGGGTTCCATC
GTTCGCCTCTACGTCATGCGCCGGAAACCCCCAGCTGAGAAGATCATAGAGATCAAGCTTATCAAAGGGC
CTAAAGGACTTGGCTTCAGCATCGCAGGGGGCGTTGGGAACCAGCACATCCCTGGAGATAATAGCATCTA
CGTAACCAAGATCATCGAAGGAGGCGCTGCCCACAAGGATGGCAGGTTGCAGATCGGAGACAAGATCCTG
GCGGTCAACAGTGTGGGGCTAGAGGATGTCATGCATGAGGACGCCGTGGCAGCCCTGAAGAACACATATG
ACGTTGTGTACCTAAAGGTGGCCAAGCCCAGCAATGCCTACCTGAGTGACAGCTATGCTCCCCCAGACAT
CACAACCTCATATTCTCAGCACCTGGACAATGAGATCAGTCATAGCAGCTACTTGGGCACCGACTACCCC
ACAGCCATGACCCCCACTTCCCCTCGGCGCTACTCCCCCGTGGCCAAGGACCTGCTAGGGGAGGAAGATA
TTCCCCGGGAACCAAGGCGGATCGTGATCCATCGGGGCTCCACCGGCCTGGGCTTCAACATTGTGGGCGG
CGAGGACGGTGAAGGCATCTTCATCTCCTTCATCCTTGCTGGGGGTCCAGCTGACCTCAGTGGGGAGCTA
CGGAAGGGGGACCAGATCCTGTCGGTCAATGGTGTTGACCTCCGCAATGCCAGTCATGAACAGGCTGCCA
TTGCCCTGAAGAACGCGGGTCAGACGGTCACGATCATCGCTCAGTATAAACCAGAAGAGTATAGCCGATT
CGAGGCCAAGATCCATGATCTTCGGGAACAGCTTATGAATAGTAGCCTGGGCTCAGGGACTGCATCTCTG
CGAAGCAACCCCAAGCGGGGCTTCTATATCAGGGCCCTGTTTGACTACGACAAGACCAAGGACTGCGGTT
TCTTGAGCCAGGCCCTGAGCTTCCACTTTGGGGATGTGCTTCATGTAATTGACGCCAGCGACGAAGAGTG
GTGGCAAGCGCGGCGGGTCCACTCTGACAGTGAGACCGATGACATTGGCTTCATTCCCAGCAAACGGCGG
GTCGAGCGACGAGAGTGGTCAAGGTTAAAGGCCAAGGACTGGGGCTCCAGCTCTGGATCACAGGGTCGAG
AAGACTCGGTTCTGAGCTATGAGACGGTGACGCAGATGGAAGTGCACTACGCTCGCCCCATCATCATCCT
TGGGCCTACCAAAGACCGTGCCAACGATGATCTTCTCTCCGAGTTCCCCGACAAGTTTGGATCCTGTGTC
CCTCATACGACACGTCCTAAGCGGGAATATGAGATAGACGGCCGCGATTACCACTTTGTCTCCTCCCGGG
AGAAAATGGAGAAGGACATTCAGGCGCACAAGTTCATTGAGGCTGGCCAGTACAACAGCCACCTCTACGG
GACCAGCGTCCAGTCTGTGCGAGAGGTAGCAGAGCAGGGGAAGCACTGCATCCTTGATGTCTCAGCCAAT
GCCGTGCGGCGGCTGCAGGCGGCCCACCTGCACCCTATCGCCATCTTCATCCGTCCCCGCTCCCTGGAGA
ATGTGCTAGAGATCAATAAGCGGATCACAGAGGAGCAAGCCCGGAAAGCCTTCGACAGGGCCACGAAGCT
GGAGCAGGAGTTCACGGAGTGCTTCTCAGCCATCGTAGAGGGCGACAGCTTTGAAGAGATCTATCACAAA
GTGAAACGTGTCATCGAAGACCTCTCAGGCCCCTACATCTGGGTCCCAGCCCGAGAGAGACTCTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001109752
Insert Size 2166 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001109752.1, NP_001103222.1
RefSeq Size 3330 bp
RefSeq ORF 2166 bp
Locus ID 13385
UniProt ID Q62108
Gene Summary Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (Probable).[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (2) contains an alternate 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 6. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 6.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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