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Mapk8ip1 (BC072578) Mouse Untagged Clone
CAT＃: MC220692
Mapk8ip1 (untagged) - Mouse mitogen activated protein kinase 8 interacting protein 1 (cDNA clone MGC:99893 IMAGE:6402485), (10ug)
CNY 9,120.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | JIP-1, IB1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC072578
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCAGCTGGTACTGAAGATGGATTCGAGCCCAGACAATGACAGCTGGTTGGAGGATCAGTGGGAGCACT GGCTCACCCATGACATCAGCCTGGAGGAGTTTGAGGATGAAGACCTTTCGGAGATCACTGACGAGTGTGG CATCAGCCTGCAGTGCAAAGACACCCTGTCTCTCCGGCCCCCGCGCGCCGGGCTGCTGTCTGCGGGTAGC AGCGGCAGCGCGGGGAGCCGGCTGCAGGCGGAGATGCTGCAGATGGACCTGATCGACGCGGCAGGTGACA TTCCGGGCGCCGAGGACGACGAGGAGGAGGAGGACGACGAGCTCGCTGCCCAACGACCAGGAGTGGGGCC TCCCAAAGCGGAGTCCAACCAGGATCCGGCGCCTCGCAGCCAGGGCCAGGGCCCGGGCACAGGCAGCGGA GACACCTACCGACCCAAGAGGCCTACCACGCTCAACCTTTTCCCGCAGGTGCCGCGGTCTCAGGACACGC TGAATAATAACTCTTTAGGCAAAAAGCACAGTTGGCAGGACCGTGTGTCTCGATCATCCTCCCCTCTGAA GACAGGAGAACAGACGCCTCCACATGAACACATCTGCCTGAGTGATGAGCTGCCACCCCAGGGCAGTCCT GTTCCCACCCAGGACCGCGGCACTTCCACCGACAGCCCTTGTCGCCGAAGTGCAGCCACCCAGATGGCAC CTCCAAGCGGTCCCCCTGCCACTGCGCCTGGTGGCCGGGGCCACTCCCATCGAGACCGAATCCACTACCA GGCAGATGTGCGGCTCGAGGCGACTGAGGAGATCTACCTGACCCCAGTGCAGAGGCCCCCAGACCCTGCA GAACCCACCTCCACCTTCATGCCACCCACGGAGAGCCGGATGTCAGTTAGCTCCGATCCAGACCCTGCCG CTTACTCTGTAACTGCGGGGCGGCCACACCCCTCCATCAGTGAAGAGGATGAGGGCTTCGACTGCCTGTC ATCCCCAGAGCGAGCTGAGCCACCAGGTGGAGGGTGGCGGGGAAGCCTCGGGGAGCCACCACCGCCTCCA CGGGCCTCACTGAGCTCGGACACCAGCGCACTGTCCTACGACTCGGTCAAGTACACACTGGTGGTGGATG AACATGCCCAGCTTGAGTTGGTGAGCCTGCGGCCGTGCTTTGGAGATTACAGTGACGAAAGCGACTCTGC CACTGTCTATGACAACTGTGCCTCTGCCTCCTCGCCCTACGAGTCAGCCATTGGTGAGGAGTATGAGGAG GCCCCTCAGCCCCGGCCTCCCACCTGCCTCTCAGAGGACTCCACCCCGGATGAGCCTGATGTCCACTTCT CTAAGAAGTTTCTGAATGTCTTCATGAGTGGCCGCTCTCGTTCCTCCAGTGCTGAGTCCTTTGGGCTGTT CTCCTGCGTCATCAATGGGGAGGAGCATGAGCAAACCCATCGGGCTATATTCAGGTTTGTGCCTCGGCAT GAAGATGAACTTGAGCTGGAAGTGGATGACCCCCTGCTGGTGGAGCTGCAGGCAGAAGACTATTGGTATG AGGCCTATAACATGCGCACCGGAGCCCGCGGGGTCTTCCCTGCCTACTATGCCATTGAGGTCACCAAGGA GCCTGAGCACATGGCAGCCCTTGCCAAAAACAGCGACTGGATTGACCAGTTCCGGGTGAAGTTCCTGGGG TCTGTCCAGGTTCCTTATCACAAGGGCAATGATGTCCTCTGTGCTGCTATGCAAAAGATCGCCACCACCC GCCGGCTCACCGTGCACTTTAACCCGCCCTCCAGCTGTGTCCTTGAGATCAGTGTCAGGGGTGTCAAGAT AGGCGTCAAAGCTGATGATGCTCTGGAGGCCAAGGGAAATAAATGTAGCCACTTCTTCCAGCTAAAGAAC ATCTCTTTCTGTGGATACCATCCAAAGAATAACAAGTACTTTGGGTTTATCACTAAGCACCCTGCTGACC ACCGGTTTGCCTGCCATGTCTTTGTGTCTGAAGATTCCACCAAAGCCCTGGCGGAGTCTGTGGGGCGTGC ATTTCAGCAGTTCTACAAGCAGTTTGTGGAGTATACCTGTCCTACAGAAGATATCTACTTGGAGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | BC072578 |
| Insert Size | 2097 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC072578, AAH72578 |
| RefSeq Size | 3138 bp |
| RefSeq ORF | 2096 bp |
| Locus ID | 19099 |
| Gene Summary | The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and thus inhibiting the JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. Appears to have a role in cell signaling in mature and developing nerve terminals. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response (By similarity). Acts as a scaffold protein that coordinates with SH3RF1 in organizing different components of the JNK pathway, including RAC1 or RAC2, MAP3K11/MLK3 or MAP3K7/TAK1, MAP2K7/MKK7, MAPK8/JNK1 and/or MAPK9/JNK2 into a functional multiprotein complex to ensure the effective activation of the JNK signaling pathway. Regulates the activation of MAPK8/JNK1 and differentiation of CD8(+) T-cells (PubMed:23963642).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210109 | Mapk8ip1 (tGFP-tagged) - Mouse mitogen activated protein kinase 8 interacting protein 1 (cDNA clone MGC:99893 IMAGE:6402485) |
CNY 7,600.00 |
|
| MR210109 | Mapk8ip1 (Myc-DDK-tagged) - Mouse mitogen activated protein kinase 8 interacting protein 1 (cDNA clone MGC:99893 IMAGE:6402485) |
CNY 6,940.00 |
|
| MR210109L3 | Lenti ORF clone of Mapk8ip1 (Myc-DDK-tagged) - Mouse mitogen activated protein kinase 8 interacting protein 1 (cDNA clone MGC:99893 IMAGE:6402485) |
CNY 8,840.00 |
|
| MR210109L4 | Lenti ORF clone of Mapk8ip1 (mGFP-tagged) - Mouse mitogen activated protein kinase 8 interacting protein 1 (cDNA clone MGC:99893 IMAGE:6402485) |
CNY 8,840.00 |
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