Mapk8ip1 (BC072578) Mouse Untagged Clone

CAT#: MC220692

Mapk8ip1 (untagged) - Mouse mitogen activated protein kinase 8 interacting protein 1 (cDNA clone MGC:99893 IMAGE:6402485), (10ug)



  "BC072578" in other vectors (4)

CNY 9,120.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms JIP-1, IB1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC072578
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCAGCTGGTACTGAAGATGGATTCGAGCCCAGACAATGACAGCTGGTTGGAGGATCAGTGGGAGCACT
GGCTCACCCATGACATCAGCCTGGAGGAGTTTGAGGATGAAGACCTTTCGGAGATCACTGACGAGTGTGG
CATCAGCCTGCAGTGCAAAGACACCCTGTCTCTCCGGCCCCCGCGCGCCGGGCTGCTGTCTGCGGGTAGC
AGCGGCAGCGCGGGGAGCCGGCTGCAGGCGGAGATGCTGCAGATGGACCTGATCGACGCGGCAGGTGACA
TTCCGGGCGCCGAGGACGACGAGGAGGAGGAGGACGACGAGCTCGCTGCCCAACGACCAGGAGTGGGGCC
TCCCAAAGCGGAGTCCAACCAGGATCCGGCGCCTCGCAGCCAGGGCCAGGGCCCGGGCACAGGCAGCGGA
GACACCTACCGACCCAAGAGGCCTACCACGCTCAACCTTTTCCCGCAGGTGCCGCGGTCTCAGGACACGC
TGAATAATAACTCTTTAGGCAAAAAGCACAGTTGGCAGGACCGTGTGTCTCGATCATCCTCCCCTCTGAA
GACAGGAGAACAGACGCCTCCACATGAACACATCTGCCTGAGTGATGAGCTGCCACCCCAGGGCAGTCCT
GTTCCCACCCAGGACCGCGGCACTTCCACCGACAGCCCTTGTCGCCGAAGTGCAGCCACCCAGATGGCAC
CTCCAAGCGGTCCCCCTGCCACTGCGCCTGGTGGCCGGGGCCACTCCCATCGAGACCGAATCCACTACCA
GGCAGATGTGCGGCTCGAGGCGACTGAGGAGATCTACCTGACCCCAGTGCAGAGGCCCCCAGACCCTGCA
GAACCCACCTCCACCTTCATGCCACCCACGGAGAGCCGGATGTCAGTTAGCTCCGATCCAGACCCTGCCG
CTTACTCTGTAACTGCGGGGCGGCCACACCCCTCCATCAGTGAAGAGGATGAGGGCTTCGACTGCCTGTC
ATCCCCAGAGCGAGCTGAGCCACCAGGTGGAGGGTGGCGGGGAAGCCTCGGGGAGCCACCACCGCCTCCA
CGGGCCTCACTGAGCTCGGACACCAGCGCACTGTCCTACGACTCGGTCAAGTACACACTGGTGGTGGATG
AACATGCCCAGCTTGAGTTGGTGAGCCTGCGGCCGTGCTTTGGAGATTACAGTGACGAAAGCGACTCTGC
CACTGTCTATGACAACTGTGCCTCTGCCTCCTCGCCCTACGAGTCAGCCATTGGTGAGGAGTATGAGGAG
GCCCCTCAGCCCCGGCCTCCCACCTGCCTCTCAGAGGACTCCACCCCGGATGAGCCTGATGTCCACTTCT
CTAAGAAGTTTCTGAATGTCTTCATGAGTGGCCGCTCTCGTTCCTCCAGTGCTGAGTCCTTTGGGCTGTT
CTCCTGCGTCATCAATGGGGAGGAGCATGAGCAAACCCATCGGGCTATATTCAGGTTTGTGCCTCGGCAT
GAAGATGAACTTGAGCTGGAAGTGGATGACCCCCTGCTGGTGGAGCTGCAGGCAGAAGACTATTGGTATG
AGGCCTATAACATGCGCACCGGAGCCCGCGGGGTCTTCCCTGCCTACTATGCCATTGAGGTCACCAAGGA
GCCTGAGCACATGGCAGCCCTTGCCAAAAACAGCGACTGGATTGACCAGTTCCGGGTGAAGTTCCTGGGG
TCTGTCCAGGTTCCTTATCACAAGGGCAATGATGTCCTCTGTGCTGCTATGCAAAAGATCGCCACCACCC
GCCGGCTCACCGTGCACTTTAACCCGCCCTCCAGCTGTGTCCTTGAGATCAGTGTCAGGGGTGTCAAGAT
AGGCGTCAAAGCTGATGATGCTCTGGAGGCCAAGGGAAATAAATGTAGCCACTTCTTCCAGCTAAAGAAC
ATCTCTTTCTGTGGATACCATCCAAAGAATAACAAGTACTTTGGGTTTATCACTAAGCACCCTGCTGACC
ACCGGTTTGCCTGCCATGTCTTTGTGTCTGAAGATTCCACCAAAGCCCTGGCGGAGTCTGTGGGGCGTGC
ATTTCAGCAGTTCTACAAGCAGTTTGTGGAGTATACCTGTCCTACAGAAGATATCTACTTGGAGTAG


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAG
GTTTAA
Restriction Sites SgfI-MluI     
ACCN BC072578
Insert Size 2097 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq BC072578, AAH72578
RefSeq Size 3138 bp
RefSeq ORF 2096 bp
Locus ID 19099
Gene Summary The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and thus inhibiting the JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. Appears to have a role in cell signaling in mature and developing nerve terminals. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins. Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response (By similarity). Acts as a scaffold protein that coordinates with SH3RF1 in organizing different components of the JNK pathway, including RAC1 or RAC2, MAP3K11/MLK3 or MAP3K7/TAK1, MAP2K7/MKK7, MAPK8/JNK1 and/or MAPK9/JNK2 into a functional multiprotein complex to ensure the effective activation of the JNK signaling pathway. Regulates the activation of MAPK8/JNK1 and differentiation of CD8(+) T-cells (PubMed:23963642).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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