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Thoc1 (NM_153552) Mouse Untagged Clone
CAT＃: MC220201
Thoc1 (untagged) - Mouse THO complex 1 (Thoc1), (10ug)
CNY 8,460.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 3110002N20Rik; AW107452; NMP-84 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC220201 representing NM_153552
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCTCCGACGCCGGCGCTTTTCAGTTTGCCGGAGGCGCGGACGCGATTTACGAAATCTACCAGAGAAG CCTTGAATAACAAAAATATCAAGCCGTTGTTGACTGCCTTCAGTCAGTTACCTGGCAGTGAAAATGAAAA AAAATGTACCCTTGACCAAGCTTTCAGAGGTGTTCTGGAAGAAGAAATTATAAATCATTCCGCATGTGAG AACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTGACCGAAAGTGTTTGTACTGCGTCCACACCAT TTGTGCTATTGGGAGATGTCTTAGACTGCCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTTGA AAAAAATGTTGCTACTTGGAAGTCAAATACATTCTATTCTGCTGGCAAAAATTATTTACTGCGTATGTGC AATGATCTCCTCAGAAGATTGTCTAAATCTCAGAATACAGTTTTCTGTGGAAGAATTCAACTCTTTTTGG CCAGGCTTTTTCCTCTATCTGAGAAATCAGGTCTTAATTTGCAGAGTCAGTTTAACCTGGAAAACGTCAC TGTTTTCAATACAAACGAGCAGGAGAGCACCCTGGGTCAGAAGCATACTGAGGATAGAGAGGAAGGGATG GATGTAGAAGAAGGTGAAATGGGAGATGATGAAGCCCCGACAACTTGTTCTATTCCAATTGATTACAACC TGTATAGAAAATTCTGGTCACTTCAGGATTACTTCAGGAACCCAGTGCAATGCTATGAGAAGATTTCTTG GAAAACGTTTCTCAAGTATTCTGAAGAAGTTTTAGCTGTTTTTAAAAGTTATAAATTAGATGATACTCAA GCCTCCAGGAAAAAGATGGAAGAATTGAAAACAGGAGGAGAGCATGTATACTTCGCCAAGTTTCTAACAA GTGAAAAGTTGATGGATTTACAACTGAGTGACAGTAACTTTCGTCGACACATCCTGTTGCAGTATCTCAT TTTATTTCAATATCTCAAGGGACAGGTCAAATTCAAAAGTTCAAATTATGTTTTAACTGATGAGCAATCA CTCTGGATTGAAGATACTACAAAATCAGTCTACCAACTGCTATCTGAAAATCCCCCTGATGGAGAAAGAT TTTCAAAGATGGTAGAGCATATATTAAACACTGAGGAAAATTGGAACTCATGGAAGAATGAAGGTTGCCC AAGTTTTGTTAAAGAAAGAGCGTCAGATACCAAGCCCACAAGAGTGGTGAGGAAGAGAGCAGCCCCAGAA GACTTCTTAGGCAAAGGGCCCAACAAGAAAATCCTCATTGGAAATGAGGAGCTCACAAGGCTTTGGAATC TCTGTCCTGATAATATGGAAGCCTGTAAATCAGAGACAAGAGAATACATGCCAACTTTGGAGGAGTTCTT TGAAGAAGCTATTGAACAAGCAGATCCTGAAAACATGGTTGAAAGTGAATATAAAGCCGTAAATAATTCA AATTATGGATGGAGAGCTCTTAGACTCTTAGCCCGGAGAAGCCCTCACTTCTTTCAGCCAACCAACCAGC AGTTTAAGAGTCTACCAGAGTATCTGGAAAACATGGTGATAAAGCTGGCCAAGGAACTACCACCCCCTTC TGAAGAAATAAAGACAGGTGAGGATGAAGACGAGGAAGATAATGATGCTTTACTAAAGGAAAATGAAAGT CCAGATGTTCGGCGAGATAAACCTATAACAGGGGAGCAGATAGAGTCATTTGCCAACAAACTTGGTGAGC AGTGGAAGATTTTGGCTCCTTACCTGGAAATTAAAGACTCTGATATTAGGCAGATTGAGTGTGACAGTGA AGACATGAAGATGAGAGCCAAGCAGCTCCTTGTTGCCTGGCAAGATCAAGAAGGAGTTCATGCAACAACT GATAACCTGATTAGTGCACTAAACAAGTCTGGATTAAGTGACCTTGCAGAAAGTCTAACTAATGACACTG AAACAAACAGTTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_153552 |
| Insert Size | 1974 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_153552.3, NP_705780.1 |
| RefSeq Size | 3855 bp |
| RefSeq ORF | 1974 bp |
| Locus ID | 225160 |
| UniProt ID | Q8R3N6 |
| Gene Summary | Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. Regulates transcriptional elongation of a subset of genes. Involved in genome stability by preventing co-transcriptional R-loop formation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209815 | Thoc1 (tGFP-tagged) - Mouse THO complex 1 (Thoc1) |
CNY 7,220.00 |
|
| MR209815 | Thoc1 (Myc-DDK-tagged) - Mouse THO complex 1 (Thoc1) |
CNY 6,560.00 |
|
| MR209815L3 | Lenti ORF clone of Thoc1 (Myc-DDK-tagged) - Mouse THO complex 1 (Thoc1) |
CNY 8,460.00 |
|
| MR209815L4 | Lenti ORF clone of Thoc1 (mGFP-tagged) - Mouse THO complex 1 (Thoc1) |
CNY 8,460.00 |
