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Ptpn11 (NM_011202) Mouse Untagged Clone
CAT＃: MC219480
Ptpn11 (untagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 1, (10ug)
CNY 7,700.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2700084A17Rik; AW536184; PTP1D; PTP2C; SAP-2; SH-PTP2; SH-PTP3; SHP-2; Shp2; Syp |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219480 representing NM_011202
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACATCGCGGAGATGGTTTCACCCCAACATCACTGGTGTGGAGGCAGAGAATCTCCTGCTGACCAGAG GAGTCGATGGCAGTTTTTTAGCAAGGCCCAGTAAGAGTAACCCTGGAGACTTCACTCTGTCTGTTAGAAG AAATGGAGCTGTTACCCACATCAAGATTCAGAACACTGGGGACTACTATGACCTCTATGGTGGGGAGAAG TTTGCCACTTTGGCTGAACTGGTTCAGTATTACATGGAACACCATGGGCAGCTGAAAGAGAAGAATGGAG ATGTTATCGAGCTCAAGTACCCGCTGAACTGTGCAGACCCTACCTCTGAAAGGTGGTTCCATGGTCACTT GTCTGGAAAAGAAGCAGAGAAGCTGCTGACGGAGAAGGGCAAGCATGGCAGCTTCCTCGTTCGAGAGAGC CAGAGCCACCCCGGAGACTTCGTTCTCTCCGTGCGCACTGGTGACGACAAAGGGGAGAGCAACGACGGCA AGTCCAAAGTGACCCACGTCATGATCCGCTGTCAGGAGCTGAAATACGACGTTGGTGGGGGAGAGCGCTT TGACTCTCTGACAGACCTGGTGGAGCATTACAAGAAGAACCCCATGGTGGAGACGCTGGGCACAGTCCTG CAGCTCAAGCAGCCCCTCAACACAACTCGTATCAATGCTGCTGAAATTGAAAGCCGGGTTCGAGAGTTAA GCAAGCTGGCTGAGACCACAGATAAAGTCAAGCAGGGCTTTTGGGAAGAGTTTGAGACGCTCCAGCAACA GGAATGCAAACTTCTCTATAGCCGAAAAGAAGGACAGAGACAAGAAAATAAAAACAAAAACAGATACAAA AACATCCTGCCCTTTGATCATACCAGGGTCGTTCTGCATGATGGGGATCCCAATGAGCCTGTTTCTGATT ACATTAATGCAAACATCATCATGCCTGAGTTTGAGACCAAGTGCAACAATTCCAAACCCAAAAAGAGTTA CATTGCCACTCAAGGCTGCCTGCAGAACACGGTGAATGACTTCTGGCGGATGGTGTTCCAGGAGAACTCT CGAGTCATTGTCATGACCACAAAGGAAGTGGAGAGAGGGAAGAGCAAATGTGTCAAGTACTGGCCTGATG AGTATGCGCTCAAAGAATACGGGGTCATGCGTGTTAGGAACGTCAAAGAAAGTGCCGCCCATGACTACAC TTTACGAGAGCTCAAACTCTCTAAGGTCGGACAAGCTCTACTCCAGGGAAACACAGAGAGAACCGTCTGG CAGTACCACTTTCGGACCTGGCCAGACCATGGCGTGCCTAGTGACCCTGGAGGTGTGCTGGACTTCCTGG AGGAGGTCCACCACAAGCAGGAGAGCATCGTGGATGCAGGCCCTGTCGTGGTTCACTGCAGCGCTGGGAT TGGCCGGACAGGAACCTTCATTGTGATTGACATCCTTATTGACATCATTCGAGAGAAAGGTGTGGACTGT GACATCGACGTTCCTAAAACCATTCAGATGGTGCGGTCCCAGAGGTCGGGGATGGTCCAGACAGAAGCAC AGTACCGGTTTATCTACATGGCTGTCCAGCACTACATAGAGACGCTGCAGCGCCGGATCGAGGAGGAGCA GAAAAGCAAAAGAAAAGGACATGAATATACCAATATTAAGTATTCCTTGGTGGACCAGACAAGTGGTGAT CAGAGTCCCCTGCCACCCTGCACCCCAACGCCACCCTGTGCAGAAATGAGGGAGGACAGCGCCCGAGTCT ATGAGAACGTGGGCCTCATGCAGCAGCAGAGGAGTTTCAGATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011202 |
| Insert Size | 1794 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_011202.3, NP_035332.1 |
| RefSeq Size | 5628 bp |
| RefSeq ORF | 1794 bp |
| Locus ID | 19247 |
| UniProt ID | P35235 |
| Gene Summary | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway. Dephosphorylates GAB1, ARHGAP35 and EGFR. Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function
,null,
Pigment cell & melanoma research
,PubMed ID 27930879
[Ptpn11]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209281 | Ptpn11 (tGFP-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11) |
CNY 8,280.00 |
|
| MR209281 | Ptpn11 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 1 |
CNY 6,680.00 |
|
| MR209281L1 | Lenti ORF clone of Ptpn11 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 1 |
CNY 7,890.00 |
|
| MR209281L2 | Lenti ORF clone of Ptpn11 (mGFP-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 1 |
CNY 9,080.00 |
|
| MR209281L3 | Lenti ORF clone of Ptpn11 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 1 |
CNY 7,890.00 |
|
| MR209281L4 | Lenti ORF clone of Ptpn11 (mGFP-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 11 (Ptpn11), transcript variant 1 |
CNY 7,890.00 |
