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Acin1 (NM_001085472) Mouse Untagged Clone
CAT＃: MC219298
Acin1 (untagged) - Mouse apoptotic chromatin condensation inducer 1 (Acin1), transcript variant 3, (10ug)
CN¥ 7,410.00
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Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2610036I19Rik; 2610510L13Rik; Acinus; acinusL; acinusS; Acn; C79325; mKIAA0670 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219298 representing NM_001085472
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATGTTCTCAGACAGCAGAGCAGGTGAAGAGAAGGAGGAAGTGACCATGGACACCAGTGAAAACAGAC CTGAAAATGAGGTGCCTGAGCCTCCTCTGCCTGTTGCAGACCAAGTCAGCAATGATGAGCGCCCAGAGGG TGGTGCTGAAGAAGAGGAAAAGAAAGAGAGTTCGATGCCCAAGTCATTCAAGAGGAAAATCTCCGTTGTC TCAGCTACCAAGGGGGTGCAAGCTGGAAACAGTGACACAGAGGGGGGCCAGCCTGGCCGAAAACGCCGTT GGGGAGCCAGCACTGCCGCGACACAGAAGAAACCGTCCATCAGTATCACCACTGAGTCACTCAAGAGCCT CATCCCCGACATCAAACCCCTGGCGGGGCAGGAGGCTGTTGTGGATCTTCATGCCGATGACTCCCGAATC TCTGAGGATGAGACAGAGCGTAATGGCGACGATGGGACCCATGACAAGGGACTGAAGATATGCCGGACAG TCACTCAGGTAGTACCCGCAGAGGGCCAGGAGAATGGGCAGAGGGAAGAGGAAGAAGAGAAAGAGCCTGA AGCCGAGCTGCCGGCGCCACCCCAGGTGTCAGTGGAGGTTGCCTTGCCCCCACCTGTGGAGCACGAAGTA AAGAAAGTAACATTAGGAGATACCTTAACCCGGAGGTCCATCAGCCAACAGAAGTCTGGAGTTTCCATTA CAATTGATGACCCAGTCCGGACCGCCCAGGTGCCCTCCCCACCCAGGGGCAAGATCAGTAACATTGTCCA CATCTCCAACCTGGTTCGTCCCTTCACTTTAGGCCAGCTGAAGGAATTATTGGGGCGTACAGGAACTTTG GTGGAAGAGGCCTTCTGGATAGACAAGATCAAATCTCATTGCTTTGTGACGTACTCTACAGTAGAGGAAG CCGTTGCCACCCGCACAGCTCTGCACGGGGTCAAGTGGCCCCAGTCCAACCCCAAATTCCTTTGTGCTGA CTATGCTGAGCAAGATGAGCTGGACTATCACCGGGGACTCTTGGTAGATCGGCCATCTGAAACTAAGGCA GAGGAACAGGGAGCACCAAGGCCCCTGCATCCCCCACCCCCACCCCCAGTCCAGCCACCGCCCCACCCCC GGGCTGAGCAGCGGGAGCAGGAAAGGGCTGTTCGAGAGCAATGGGCAGAACGGGAACGGGAAATGGAGCG CCGGGAGAGGACTCGGTCTGAGAGAGAATGGGATCGGGACAAAGTTCGAGAGGGACCCCGCTCCCGATCA CGGTCCCGTGACCGCCGCCGGAAAGAGCGAGCAAAATCTAAAGAAAAGAAGAGTGAAAAGAAAGAAAAAG CCCAGGAGGAGCCACCTGCCAAGCTGCTGGATGACCTCTTCCGTAAGACTAAGGCAGCTCCCTGCATCTA TTGGCTCCCTCTGACTGAGAGCCAAATTGTTCAGAAGGAGGCAGAGCAAGCTGAACGGGCCAAGGAGCGG GAGAAGCGGCGAAAAGAACGAGAAGAAGAAGAACAAAAGGAACGGGAGAAGGAAGCTGAGCGGGAACGGA ACCGGCAGCTAGAACGGGAGAAGAGGAGGGAGCACAGCAGGGAGAGAGAGAGGGACAGGGAGAGAGAGCG GGACAGGGGTGACCGAGAGCGGGAGAGGGAGCGAGACCGAGACCGAGGCAGGGAGAGGGATCGCAGAGAC ACCAAGCGCCACAGCAGAAGCCGGAGTCGAAGCACACCTGTACGGGACCGGGGTGGGCGCCGCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001085472 |
| Insert Size | 1746 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001085472.2, NP_001078941.2 |
| RefSeq Size | 2390 bp |
| RefSeq ORF | 1746 bp |
| Locus ID | 56215 |
| Gene Summary | Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, compared to variant 1. The resulting isoform (3) is shorter at the N-terminus, compared to isoform 1. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG224597 | Acin1 (tGFP-tagged) - Mouse apoptotic chromatin condensation inducer 1 (Acin1) transcript variant 3, (10ug) |
CN¥ 6,370.00 |
|
| MR224597 | Acin1 (Myc-DDK-tagged) - Mouse apoptotic chromatin condensation inducer 1 (Acin1), transcript variant 3 |
CN¥ 5,800.00 |
|
| MR224597L3 | Lenti ORF clone of Acin1 (Myc-DDK-tagged) - Mouse apoptotic chromatin condensation inducer 1 (Acin1), transcript variant 3 |
CN¥ 7,700.00 |
|
| MR224597L4 | Lenti ORF clone of Acin1 (mGFP-tagged) - Mouse apoptotic chromatin condensation inducer 1 (Acin1), transcript variant 3 |
CN¥ 7,700.00 |
