Nr5a2 (NM_030676) Mouse Untagged Clone
CAT#: MC218968
Nr5a2 (untagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1, (10ug)
CNY 4,176.00
CNY 7,130.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | AU020803; D1Ertd308e; Ftf; LRH-1; UF2-H3B |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC218968 representing NM_030676
Red=Cloning site Blue=ORF TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCTGCTAGTTTGGATACTGGAGATTTTCAAGAATTTCTTAAGCATGGACTTACAGCTATTGCGTCTG CACCAGGGTCAGAGACTCGCCACTCCCCCAAACGTGAGGAACAACTCCGGGAAAAACGTGCTGGGCTTCC GGACCGACACCGACGCCCCATTCCCGCCCGCAGCCGCCTTGTCATGCTGCCCAAAGTGGAGACGGAAGCC CCAGGACTGGTCCGATCGCATGGGGAACAGGGGCAGATGCCAGAAAACATGCAAGTGTCTCAATTTAAAA TGGTGAATTACTCCTATGATGAAGATCTGGAAGAGCTATGTCCTGTGTGTGGCGATAAAGTGTCTGGGTA CCATTACGGTCTCCTCACGTGCGAAAGCTGCAAGGGTTTTTTTAAGCGAACTGTCCAAAACCAAAAAAGG TACACGTGCATAGAGAACCAGAATTGCCAAATTGACAAAACGCAGAGAAAACGATGTCCCTACTGTCGAT TCAAAAAATGTATCGATGTTGGGATGAAGCTGGAAGCCGTAAGAGCCGACCGCATGCGAGGGGGCAGAAA TAAGTTTGGGCCAATGTACAAGAGAGACAGGGCTTTGAAGCAGCAGAAGAAAGCCCTCATTCGAGCCAAT GGACTTAAGCTGGAAGCCATGTCTCAGGTGATCCAAGCAATGCCCTCAGACCTGACCTCTGCAATTCAGA ACATTCATTCCGCCTCCAAAGGCCTACCTCTGAGCCATGTAGCCTTGCCTCCGACAGACTATGACAGAAG TCCCTTTGTCACATCTCCCATTAGCATGACAATGCCACCTCACAGCAGCCTGCATGGTTACCAACCCTAT GGTCACTTTCCTAGTCGGGCCATCAAGTCTGAGTACCCAGACCCCTACTCCAGCTCACCTGAGTCAATGA TGGGTTACTCCTACATGGATGGTTACCAGACAAACTCCCCGGCCAGCATCCCACACCTGATACTGGAACT TTTGAAGTGTGAACCAGATGAGCCTCAAGTTCAAGCGAAGATCATGGCTTACCTCCAGCAAGAGCAGAGT AACCGAAACAGGCAAGAAAAGCTGAGCGCATTTGGGCTTTTATGCAAAATGGCGGACCAGACCCTGTTCT CCATTGTTGAGTGGGCCAGGAGTAGTATCTTCTTCAGGGAACTGAAGGTTGATGACCAAATGAAGCTGCT TCAAAACTGCTGGAGTGAGCTCTTGATTCTCGATCACATTTACCGACAAGTGGCGCATGGGAAGGAAGGG ACAATCTTCCTGGTTACTGGAGAACACGTGGACTACTCCACCATCATCTCACACACAGAAGTCGCGTTCA ACAACCTCCTGAGTCTCGCACAGGAGCTGGTGGTGAGGCTCCGTTCCCTTCAGTTCGATCAGCGGGAGTT TGTATGTCTCAAGTTCCTGGTGCTGTTCAGCTCAGATGTGAAGAACCTGGAGAACCTGCAGCTGGTGGAA GGTGTCCAAGAGCAGGTGAATGCCGCCCTGCTGGACTACACGGTTTGCAACTACCCACAACAGACTGAGA AATTCGGACAGCTACTTCTTCGGCTACCCGAGATCCGGGCAATCAGCAAGCAGGCAGAAGACTACCTGTA CTATAAGCACGTGAACGGGGATGTGCCCTATAATAACCTCCTCATTGAGATGCTGCATGCCAAAAGAGCC TAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Chromatograms |
CHROMATOGRAMS
Sequencher program is needed, download here. |
Restriction Sites | SgfI-MluI |
ACCN | NM_030676 |
Insert Size | 1683 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC137845, AAI37846 |
RefSeq Size | 2762 bp |
RefSeq ORF | 1683 bp |
Locus ID | 26424 |
UniProt ID | P45448 |
Gene Summary | Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development (By similarity). Activates the transcription of CYP2C38 (PubMed:30555544).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG225371 | Nr5a2 (tGFP-tagged) - Mouse nuclear receptor subfamily 5 group A member 2 (Nr5a2) transcript variant 1, (10ug) |
CNY 5,420.00 |
|
MR225371 | Nr5a2 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1 |
CNY 4,168.00 |
|
MR225371L3 | Lenti ORF clone of Nr5a2 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1 |
CNY 6,568.00 |
|
MR225371L4 | Lenti ORF clone of Nr5a2 (mGFP-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1 |
CNY 6,840.00 |