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Nr5a2 (NM_030676) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR225371L4V
- LentiORF®
-
Lenti ORF particles, Nr5a2 (GFP-tagged) - Mouse nuclear receptor subfamily 5, group A, member 2 (Nr5a2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 11,305.00
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Specifications
| Product Data | |
| Product Name | Nr5a2 (NM_030676) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AU020803; D1Ertd308e; Ftf; LRH-1; UF2-H3B |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_030676 |
| ORF Size | 1680 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR225371).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_030676.3, NP_109601.1 |
| RefSeq Size | 3720 bp |
| RefSeq ORF | 1683 bp |
| Locus ID | 26424 |
| Gene Summary | Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development (By similarity). Activates the transcription of CYP2C38 (PubMed:30555544).[UniProtKB/Swiss-Prot Function] |
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