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Creb3l2 (NM_178661) Mouse Untagged Clone
CAT＃: MC217510
Creb3l2 (untagged) - Mouse cAMP responsive element binding protein 3-like 2 (Creb3l2), (10ug)
CNY 3,888.00
CNY 6,750.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | BBF2H7; C530025K05Rik; SCIRR69 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC217510 representing NM_178661
Red=Cloning site Blue=ORF TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGTGCTGGAGAGCGGGGAGCAGAGCGTCCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGC CCGGAGAGACTGAGGCCCTCATGTACCACACGCACTTCTCGGAGCTCCTAGACGAGTTTTCCCAGAACGT CCTGGGTCAGCTCCTGAGTGACCCTTTCCTCTCAGAGAAGAGCGAGTCAATGGAGGTGGAGCCATCTCCA ACATCACCAGCGCCTCTCATCCAGGCTGAACACAGCTACTCTCTGAGCGAGGAGCCCCGGACTCAGTCAC CATTTACCCATGCGGCTACCAGCGACAGCTTCAATGACGAGGAGGTGGAGAGTGAAAAATGGTACCTGTC TACAGAGTTTCCTTCAGCTACCATCAAGACAGAGCCAATCACAGAGGAGCAGCCCCCGGGACTTGTCCCT TCTGTCACTCTGACCATCACAGCCATTTCCACTCCTTTTGAAAAAGAAGAGTCCCCTCTGGATATGAATG CTGGGGGGGACTCCTCGTGCCAGACGCTTATTCCTAAGATTAAGCTGGAGCCGCACGAAGTGGATCAGTT CTTAAACTTCTCCCCGAAAGAAGCCTCCGTGGATCAACTGCACTTACCACCAACACCACCCAGTAGTCAC AGCAGTGACTCTGAGGGCAGCTTGAGCCCCAACCCACGCCTGCATCCCTTCAGCCTGTCTCAGGCCCACA GCCCTGCCAGAGCCATGCCCCGGGGCCCCTCTGCCTTGTCCACATCTCCTCTCCTCACAGCTCCACATAA GCTGCAGGGATCGGGCCCCCTGGTCCTGACAGAAGAGGAGAAGAGGACCCTGGTTGCCGAGGGCTATCCC ATTCCCACCAAGCTGCCTCTGACAAAATCTGAGGAGAAGGCCCTGAAGAAAATCCGGAGAAAGATCAAGA ATAAGATTTCTGCCCAAGAAAGCAGGAGAAAGAAGAAAGAATACATGGACAGCCTGGAGAAAAAAGTGGA GTCTTGTTCAACTGAGAACTTGGAGCTTCGGAAGAAGGTGGAGGTGCTGGAGAACACCAATAGGACTCTC CTTCAGCAACTTCAGAAGCTTCAGACTTTGGTGATGGGGAAGGTCTCTCGAACCTGCAAGTTAGCTGGCA CACAGACTGGCACCTGCCTCATGGTCGTTGTGCTTTGCTTTGCTGTTGCATTTGGAAGCTTCTTTCAAGG CTATGGGCCTTATCCTTCTGCCACCAAGATGGCTCTGCCCAGCCAGCATCCTCTGTCAGAGCCATACACA GCCTCCGTGGTGAGATCCAGGAACCTGCTAATCTATGAGGAACACGCTCCCCTGGAAGAGTCGTCGAGCC CAGCCTCAGCCGGGGAGCTGGGGGGCTGGGACAGAGGCTCCTCTCTGCTCAGGGCATCGTCGGGGCTTGA GGCCCTGCCAGAGGTGGATCTTCCCCATTTCCTTATCTCCAATGAGACGAGCTTGGAGAAGTCAGTACTG TTGGAGCTTCAGCAGCACCTGGTCAGCAGCAAACTGGAAGGGAACGAAACACTCAAGGTTGTAGAGCTGG AGAGGAGAGTGAACGCCACCTTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_178661 |
| Insert Size | 1566 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC043466, AAH43466 |
| RefSeq Size | 3188 bp |
| RefSeq ORF | 1566 bp |
| Locus ID | 208647 |
| UniProt ID | Q8BH52 |
| Gene Summary | Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (PubMed:19767744). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222325 | Creb3l2 (tGFP-tagged) - Mouse cAMP responsive element binding protein 3-like 2 (Creb3l2), (10ug) |
CNY 5,040.00 |
|
| MR222325 | Creb3l2 (Myc-DDK-tagged) - Mouse cAMP responsive element binding protein 3-like 2 (Creb3l2) |
CNY 3,880.00 |
|
| MR222325L3 | Lenti ORF clone of Creb3l2 (Myc-DDK-tagged) - Mouse cAMP responsive element binding protein 3-like 2 (Creb3l2) |
CNY 6,460.00 |
|
| MR222325L4 | Lenti ORF clone of Creb3l2 (mGFP-tagged) - Mouse cAMP responsive element binding protein 3-like 2 (Creb3l2) |
CNY 6,460.00 |
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